Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana

Background: Endometriosis affects at least 15% of infertile women. The diagnosis is made by direct visualization of implants either at laparoscopy or laparotomy. Elevation of plasma CA-125 levels has been associated with the presence of endometriosis. Aim: To search for a correlation between CA-125...

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Autores principales: Bianchi P,Marcelo, Macaya P,Rodrigo, Guillermo,Durruty V, Manzur Y.,Alejandro
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2003
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000400003
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spelling oai:scielo:S0034-988720030004000032004-12-13Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelvianaBianchi P,MarceloMacaya P,RodrigoGuillermo,Durruty VManzur Y.,Alejandro CA-125 antigen Endometriosis Laparoscopy Background: Endometriosis affects at least 15% of infertile women. The diagnosis is made by direct visualization of implants either at laparoscopy or laparotomy. Elevation of plasma CA-125 levels has been associated with the presence of endometriosis. Aim: To search for a correlation between CA-125 and the presence of endometriosis and its severity, among infertile patients requesting a diagnostic laparoscopy. Patients and methods: A total of 117 women were prospectively enrolled in the study between May 2000 and March 2002. A serum sample for CA-125 was taken immediately before surgery and the value obtained was correlated with the presence or absence of endometriosis and the severity of the disease. Results: Sixty nine patients had endometriosis (59%). Patients with severe endometriosis, or grade IV, showed statistically significant higher levels of CA-125 compared to women without endometriosis or with grades I, II or III of the disease. Discussion: The overall sensibility of CA-125 in detecting patients with endometriosis was low, however, it worked better for patients with advanced disease. Considering the rather low cost and simplicity of the test, we believe that it should be included in the evaluation of infertile couples (Rev Méd Chile 2003; 131: 367-72).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.131 n.4 20032003-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000400003es10.4067/S0034-98872003000400003
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic CA-125 antigen
Endometriosis
Laparoscopy
spellingShingle CA-125 antigen
Endometriosis
Laparoscopy
Bianchi P,Marcelo
Macaya P,Rodrigo
Guillermo,Durruty V
Manzur Y.,Alejandro
Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana
description Background: Endometriosis affects at least 15% of infertile women. The diagnosis is made by direct visualization of implants either at laparoscopy or laparotomy. Elevation of plasma CA-125 levels has been associated with the presence of endometriosis. Aim: To search for a correlation between CA-125 and the presence of endometriosis and its severity, among infertile patients requesting a diagnostic laparoscopy. Patients and methods: A total of 117 women were prospectively enrolled in the study between May 2000 and March 2002. A serum sample for CA-125 was taken immediately before surgery and the value obtained was correlated with the presence or absence of endometriosis and the severity of the disease. Results: Sixty nine patients had endometriosis (59%). Patients with severe endometriosis, or grade IV, showed statistically significant higher levels of CA-125 compared to women without endometriosis or with grades I, II or III of the disease. Discussion: The overall sensibility of CA-125 in detecting patients with endometriosis was low, however, it worked better for patients with advanced disease. Considering the rather low cost and simplicity of the test, we believe that it should be included in the evaluation of infertile couples (Rev Méd Chile 2003; 131: 367-72).
author Bianchi P,Marcelo
Macaya P,Rodrigo
Guillermo,Durruty V
Manzur Y.,Alejandro
author_facet Bianchi P,Marcelo
Macaya P,Rodrigo
Guillermo,Durruty V
Manzur Y.,Alejandro
author_sort Bianchi P,Marcelo
title Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana
title_short Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana
title_full Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana
title_fullStr Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana
title_full_unstemmed Correlación entre valores del marcador Ca-125 con la presencia y severidad de endometriosis pelviana
title_sort correlación entre valores del marcador ca-125 con la presencia y severidad de endometriosis pelviana
publisher Sociedad Médica de Santiago
publishDate 2003
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000400003
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