Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999

Background: Several maternal diseases, such as diabetes mellitus or high blood pressure, are associated with a higher risk for fetal or neonatal problems. Aim: To study the association between chronic diseases of the mother and congenital malformations. Material and methods: Review of the records of...

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Autores principales:	Ordóñez A,María Paz, Nazer H,Julio, Aguila R,Alfredo, Cifuentes O,Lucía
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2003
Materias:	Abnormalities Fetal diseases Pregnancy high risk Pregnancy in diabetes
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000400008
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spelling	oai:scielo:S0034-988720030004000082004-12-13Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999Ordóñez A,María PazNazer H,JulioAguila R,AlfredoCifuentes O,Lucía Abnormalities Fetal diseases Pregnancy high risk Pregnancy in diabetes Background: Several maternal diseases, such as diabetes mellitus or high blood pressure, are associated with a higher risk for fetal or neonatal problems. Aim: To study the association between chronic diseases of the mother and congenital malformations. Material and methods: Review of the records of the Latin American Collaborative Study of Congenital Malformations (ECLAMC) at the University of Chile Clinical Hospital. A sample of 383 mothers with a chronic disease was compared with 297 healthy mothers. The presence of congenital malformations in the newborns was studied. The odds ratio (OR) of a mother to have a child with a congenital malformation was calculated. Results: Mothers with bronchial asthma, diabetes mellitus, hypertension and hypothyroidism had an OR over 1 of having a child with a congenital malformation. No association between maternal obesity and offspring malformations was observed. Offspring of diabetic mothers had 8.95 times more probabilities of having a major malformation and 4.95 times more probabilities of having a minor defect. Conclusions: Offspring of mothers with diabetes mellitus, bronchial asthma, hypertension or hypothyroidism have a higher risk of presenting a congenital malformation, when compared with offspring of healthy mothers (Rev Méd Chile 2003; 131: 404-11).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.131 n.4 20032003-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000400008es10.4067/S0034-98872003000400008
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Abnormalities Fetal diseases Pregnancy high risk Pregnancy in diabetes
spellingShingle	Abnormalities Fetal diseases Pregnancy high risk Pregnancy in diabetes Ordóñez A,María Paz Nazer H,Julio Aguila R,Alfredo Cifuentes O,Lucía Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999
description	Background: Several maternal diseases, such as diabetes mellitus or high blood pressure, are associated with a higher risk for fetal or neonatal problems. Aim: To study the association between chronic diseases of the mother and congenital malformations. Material and methods: Review of the records of the Latin American Collaborative Study of Congenital Malformations (ECLAMC) at the University of Chile Clinical Hospital. A sample of 383 mothers with a chronic disease was compared with 297 healthy mothers. The presence of congenital malformations in the newborns was studied. The odds ratio (OR) of a mother to have a child with a congenital malformation was calculated. Results: Mothers with bronchial asthma, diabetes mellitus, hypertension and hypothyroidism had an OR over 1 of having a child with a congenital malformation. No association between maternal obesity and offspring malformations was observed. Offspring of diabetic mothers had 8.95 times more probabilities of having a major malformation and 4.95 times more probabilities of having a minor defect. Conclusions: Offspring of mothers with diabetes mellitus, bronchial asthma, hypertension or hypothyroidism have a higher risk of presenting a congenital malformation, when compared with offspring of healthy mothers (Rev Méd Chile 2003; 131: 404-11).
author	Ordóñez A,María Paz Nazer H,Julio Aguila R,Alfredo Cifuentes O,Lucía
author_facet	Ordóñez A,María Paz Nazer H,Julio Aguila R,Alfredo Cifuentes O,Lucía
author_sort	Ordóñez A,María Paz
title	Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999
title_short	Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999
title_full	Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999
title_fullStr	Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999
title_full_unstemmed	Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999
title_sort	malformaciones congénitas y patología crónica de la madre.: estudio eclamc 1971-1999
publisher	Sociedad Médica de Santiago
publishDate	2003
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000400008
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Malformaciones congénitas y patología crónica de la madre.: Estudio ECLAMC 1971-1999

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