Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes

Background: Kaposi sarcoma is the most common tumor in HIV infected patients. Aim: To describe a cohort of patients with Kaposi sarcoma. Material and methods: Retrospective review of HIV patients with Kaposi sarcoma seen at a public hospital and at a HIV clinic. Detailed description of patients subj...

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Autores principales:	Lasso B,Martín, Pérez G,Jorge, Noriega R,Luis, Malebrán R,Andrea, Espinoza V,Susana
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2003
Materias:	Drug therapy Drug therapy, combination HIV infections Sarcoma, Kaposi
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000500002
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spelling	oai:scielo:S0034-988720030005000022004-12-13Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientesLasso B,MartínPérez G,JorgeNoriega R,LuisMalebrán R,AndreaEspinoza V,Susana Drug therapy Drug therapy, combination HIV infections Sarcoma, Kaposi Background: Kaposi sarcoma is the most common tumor in HIV infected patients. Aim: To describe a cohort of patients with Kaposi sarcoma. Material and methods: Retrospective review of HIV patients with Kaposi sarcoma seen at a public hospital and at a HIV clinic. Detailed description of patients subjected to antiretroviral treatment and chemotherapy. Results: Between 1995 and 2002, 1127 HIV infected patients were seen. Of these, 78 had Kaposi sarcoma, 15 were treated with high activity antiretroviral therapy (HAART) and 17 with HAART and chemotherapy. These 32 patients were male, and their mean age was 33±6 years. The initial CD4 count in 27 of these was 95±105 cells/ml. The initial viral load in 18 of these was 370,246±768,693 RNA copies/ml. Of the 15 patients treated with HAART, eight had a complete remission, one had a partial response, one remained stationary and five died. Of the 17 patients treated with HAART and chemotherapy, seven had complete remission, five had a partial response, 2 remained stationary and three died. The lapse of complete remission was 272 days for those treated with HAART and 292 days for those treated with HAART and chemotherapy. Conclusions: In HIV patients with Kaposi sarcoma, high activity antiretroviral therapy, associated or not to chemotherapy, induces complete remission in 46% of patients and partial remission in 16% (Rev Méd Chile 2003; 131: 483-90).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.131 n.5 20032003-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000500002es10.4067/S0034-98872003000500002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Drug therapy Drug therapy, combination HIV infections Sarcoma, Kaposi
spellingShingle	Drug therapy Drug therapy, combination HIV infections Sarcoma, Kaposi Lasso B,Martín Pérez G,Jorge Noriega R,Luis Malebrán R,Andrea Espinoza V,Susana Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes
description	Background: Kaposi sarcoma is the most common tumor in HIV infected patients. Aim: To describe a cohort of patients with Kaposi sarcoma. Material and methods: Retrospective review of HIV patients with Kaposi sarcoma seen at a public hospital and at a HIV clinic. Detailed description of patients subjected to antiretroviral treatment and chemotherapy. Results: Between 1995 and 2002, 1127 HIV infected patients were seen. Of these, 78 had Kaposi sarcoma, 15 were treated with high activity antiretroviral therapy (HAART) and 17 with HAART and chemotherapy. These 32 patients were male, and their mean age was 33±6 years. The initial CD4 count in 27 of these was 95±105 cells/ml. The initial viral load in 18 of these was 370,246±768,693 RNA copies/ml. Of the 15 patients treated with HAART, eight had a complete remission, one had a partial response, one remained stationary and five died. Of the 17 patients treated with HAART and chemotherapy, seven had complete remission, five had a partial response, 2 remained stationary and three died. The lapse of complete remission was 272 days for those treated with HAART and 292 days for those treated with HAART and chemotherapy. Conclusions: In HIV patients with Kaposi sarcoma, high activity antiretroviral therapy, associated or not to chemotherapy, induces complete remission in 46% of patients and partial remission in 16% (Rev Méd Chile 2003; 131: 483-90).
author	Lasso B,Martín Pérez G,Jorge Noriega R,Luis Malebrán R,Andrea Espinoza V,Susana
author_facet	Lasso B,Martín Pérez G,Jorge Noriega R,Luis Malebrán R,Andrea Espinoza V,Susana
author_sort	Lasso B,Martín
title	Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes
title_short	Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes
title_full	Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes
title_fullStr	Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes
title_full_unstemmed	Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes
title_sort	sarcoma de kaposi y vih: tratamiento antirretroviral y quimioterapia en 32 pacientes
publisher	Sociedad Médica de Santiago
publishDate	2003
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000500002
work_keys_str_mv	AT lassobmartin sarcomadekaposiyvihtratamientoantirretroviralyquimioterapiaen32pacientes AT perezgjorge sarcomadekaposiyvihtratamientoantirretroviralyquimioterapiaen32pacientes AT noriegarluis sarcomadekaposiyvihtratamientoantirretroviralyquimioterapiaen32pacientes AT malebranrandrea sarcomadekaposiyvihtratamientoantirretroviralyquimioterapiaen32pacientes AT espinozavsusana sarcomadekaposiyvihtratamientoantirretroviralyquimioterapiaen32pacientes
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Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes

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