Infecciones por virus varicela zoster en menores de 15 años con cáncer

Background: Infections caused by Varicella Zoster virus in children with cancer have a high rate of complications and mortality. Aim: To report the outcome of this infection in children with cancer. Patients and methods: Retrospective analysis of medical records of 216 children aged less than 15 yea...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Folatre B,sabel, Zolezzi R,Paola, Schmidt K,Daniela, Marín H,Francisco, Täger F,Marlis
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2003
Materias:	Acyclovir Herpes Zoster Neoplasms Varicellovirus
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000700007
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872003000700007
record_format	dspace
spelling	oai:scielo:S0034-988720030007000072004-12-13Infecciones por virus varicela zoster en menores de 15 años con cáncerFolatre B,sabelZolezzi R,PaolaSchmidt K,DanielaMarín H,FranciscoTäger F,Marlis Acyclovir Herpes Zoster Neoplasms Varicellovirus Background: Infections caused by Varicella Zoster virus in children with cancer have a high rate of complications and mortality. Aim: To report the outcome of this infection in children with cancer. Patients and methods: Retrospective analysis of medical records of 216 children aged less than 15 years old with the diagnosis of an hematological or solid tumor, admitted to the National Program of Antineoplastic Drugs (PINDA). Results: Eighty seven children had a Varicella Zoster virus infections, 73 (84%) had varicella, 8 (9%) had herpes zoster and 6 (7%) had varicella and herpes zoster. Ninety four percent acquired the infection during antineoplastic treatment and 78% received Acyclovir as antiviral therapy. During a nosocomial outbreak of varicella, three patients with an Acute Lymphoblastic leukemia died in the initial phase of chemotherapy, in spite of an early administration of Acyclovir. No patient with herpes zoster died. Conclusions: The incidence of varicella was higher in children with leukemia or lymphoma than in children with other types of cancer. Virus reactivation was uncommon and had a benign course. Varicella mortality in these children could be favorably modified through an active immunization of immunocompetent children (Rev Méd Chile 2003; 133: 759-64)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.131 n.7 20032003-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000700007es10.4067/S0034-98872003000700007
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Acyclovir Herpes Zoster Neoplasms Varicellovirus
spellingShingle	Acyclovir Herpes Zoster Neoplasms Varicellovirus Folatre B,sabel Zolezzi R,Paola Schmidt K,Daniela Marín H,Francisco Täger F,Marlis Infecciones por virus varicela zoster en menores de 15 años con cáncer
description	Background: Infections caused by Varicella Zoster virus in children with cancer have a high rate of complications and mortality. Aim: To report the outcome of this infection in children with cancer. Patients and methods: Retrospective analysis of medical records of 216 children aged less than 15 years old with the diagnosis of an hematological or solid tumor, admitted to the National Program of Antineoplastic Drugs (PINDA). Results: Eighty seven children had a Varicella Zoster virus infections, 73 (84%) had varicella, 8 (9%) had herpes zoster and 6 (7%) had varicella and herpes zoster. Ninety four percent acquired the infection during antineoplastic treatment and 78% received Acyclovir as antiviral therapy. During a nosocomial outbreak of varicella, three patients with an Acute Lymphoblastic leukemia died in the initial phase of chemotherapy, in spite of an early administration of Acyclovir. No patient with herpes zoster died. Conclusions: The incidence of varicella was higher in children with leukemia or lymphoma than in children with other types of cancer. Virus reactivation was uncommon and had a benign course. Varicella mortality in these children could be favorably modified through an active immunization of immunocompetent children (Rev Méd Chile 2003; 133: 759-64)
author	Folatre B,sabel Zolezzi R,Paola Schmidt K,Daniela Marín H,Francisco Täger F,Marlis
author_facet	Folatre B,sabel Zolezzi R,Paola Schmidt K,Daniela Marín H,Francisco Täger F,Marlis
author_sort	Folatre B,sabel
title	Infecciones por virus varicela zoster en menores de 15 años con cáncer
title_short	Infecciones por virus varicela zoster en menores de 15 años con cáncer
title_full	Infecciones por virus varicela zoster en menores de 15 años con cáncer
title_fullStr	Infecciones por virus varicela zoster en menores de 15 años con cáncer
title_full_unstemmed	Infecciones por virus varicela zoster en menores de 15 años con cáncer
title_sort	infecciones por virus varicela zoster en menores de 15 años con cáncer
publisher	Sociedad Médica de Santiago
publishDate	2003
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000700007
work_keys_str_mv	AT folatrebsabel infeccionesporvirusvaricelazosterenmenoresde15anosconcancer AT zolezzirpaola infeccionesporvirusvaricelazosterenmenoresde15anosconcancer AT schmidtkdaniela infeccionesporvirusvaricelazosterenmenoresde15anosconcancer AT marinhfrancisco infeccionesporvirusvaricelazosterenmenoresde15anosconcancer AT tagerfmarlis infeccionesporvirusvaricelazosterenmenoresde15anosconcancer
_version_	1718436101581963264

Infecciones por virus varicela zoster en menores de 15 años con cáncer

Ejemplares similares