Demencia por déficit de vitamina B12: Caso clínico

Cyanocobalamin (vitamin B12) deficiency can cause polyneuropathy, myelopathy, blindness, confusion, psychosis and dementia. Nonetheless, its deficiency as the sole cause of dementia is infrequent. We report a 59 years old man with a 6 months history of progressive loss of memory, disorientation, apa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Behrens P,María Isabel, Díaz T,Violeta, Vásquez V,Carolina, Donoso S,Archibaldo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2003
Materias:	Dementia Tomography emiss on computed single photon Vitamin B12 deficiency
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000800012
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872003000800012
record_format	dspace
spelling	oai:scielo:S0034-988720030008000122004-12-13Demencia por déficit de vitamina B12: Caso clínicoBehrens P,María IsabelDíaz T,VioletaVásquez V,CarolinaDonoso S,Archibaldo Dementia Tomography emiss on computed single photon Vitamin B12 deficiency Cyanocobalamin (vitamin B12) deficiency can cause polyneuropathy, myelopathy, blindness, confusion, psychosis and dementia. Nonetheless, its deficiency as the sole cause of dementia is infrequent. We report a 59 years old man with a 6 months history of progressive loss of memory, disorientation, apathy, paranoid delusions, gait difficulties with falls, and urinary incontinence. He had suffered a similar episode 3 years before, with a complete remission. On examination there was frontal type dementia with Korsakoff syndrome, a decrease in propioception and ataxic gait. Cerebrospinal fluid examination showed a protein of 0.42 g/L. Brain computed tomography showed sequelae of a frontal left trauma. Brain single photon computed tomography (SPECT) was normal. Complete blood count showed a macrocytic anemia with a hematocrit 29% and a mean corpuscular volume of 117 µ3. Plasma vitamin B12 levels were undetectable, erythrocyte folate levels were 3.9 ng/ml and plasma folate was normal. The myelogram showed megaloblastosis and the gastric biopsy showed atrophic gastritis. Treatment with parenteral B12 vitamin and folic acid reverted the symptoms, with normalization of the neuropsychological tests and reintegration to work (Rev Méd Chile 2003; 131: 915-9)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.131 n.8 20032003-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000800012es10.4067/S0034-98872003000800012
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Dementia Tomography emiss on computed single photon Vitamin B12 deficiency
spellingShingle	Dementia Tomography emiss on computed single photon Vitamin B12 deficiency Behrens P,María Isabel Díaz T,Violeta Vásquez V,Carolina Donoso S,Archibaldo Demencia por déficit de vitamina B12: Caso clínico
description	Cyanocobalamin (vitamin B12) deficiency can cause polyneuropathy, myelopathy, blindness, confusion, psychosis and dementia. Nonetheless, its deficiency as the sole cause of dementia is infrequent. We report a 59 years old man with a 6 months history of progressive loss of memory, disorientation, apathy, paranoid delusions, gait difficulties with falls, and urinary incontinence. He had suffered a similar episode 3 years before, with a complete remission. On examination there was frontal type dementia with Korsakoff syndrome, a decrease in propioception and ataxic gait. Cerebrospinal fluid examination showed a protein of 0.42 g/L. Brain computed tomography showed sequelae of a frontal left trauma. Brain single photon computed tomography (SPECT) was normal. Complete blood count showed a macrocytic anemia with a hematocrit 29% and a mean corpuscular volume of 117 µ3. Plasma vitamin B12 levels were undetectable, erythrocyte folate levels were 3.9 ng/ml and plasma folate was normal. The myelogram showed megaloblastosis and the gastric biopsy showed atrophic gastritis. Treatment with parenteral B12 vitamin and folic acid reverted the symptoms, with normalization of the neuropsychological tests and reintegration to work (Rev Méd Chile 2003; 131: 915-9)
author	Behrens P,María Isabel Díaz T,Violeta Vásquez V,Carolina Donoso S,Archibaldo
author_facet	Behrens P,María Isabel Díaz T,Violeta Vásquez V,Carolina Donoso S,Archibaldo
author_sort	Behrens P,María Isabel
title	Demencia por déficit de vitamina B12: Caso clínico
title_short	Demencia por déficit de vitamina B12: Caso clínico
title_full	Demencia por déficit de vitamina B12: Caso clínico
title_fullStr	Demencia por déficit de vitamina B12: Caso clínico
title_full_unstemmed	Demencia por déficit de vitamina B12: Caso clínico
title_sort	demencia por déficit de vitamina b12: caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2003
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003000800012
work_keys_str_mv	AT behrenspmariaisabel demenciapordeficitdevitaminab12casoclinico AT diaztvioleta demenciapordeficitdevitaminab12casoclinico AT vasquezvcarolina demenciapordeficitdevitaminab12casoclinico AT donososarchibaldo demenciapordeficitdevitaminab12casoclinico
_version_	1718436107253710848

Demencia por déficit de vitamina B12: Caso clínico

Ejemplares similares