Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casos

Severe aplastic anemia has an elevated mortality if treatment is unsatisfactory. Immunosuppression is the treatment of choice in adults, comparable with allogeneic bone marrow transplant in children. We report two adult patients (both males, aged 59 and 67 years old) who were treated successfully wi...

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Autores principales:	Cabrera C,M Elena, Pinto A,Delia
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2003
Materias:	Anemia aplastic Cyclosporine thromocytopenia
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003001200012
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spelling	oai:scielo:S0034-988720030012000122004-04-16Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casosCabrera C,M ElenaPinto A,Delia Anemia aplastic Cyclosporine thromocytopenia Severe aplastic anemia has an elevated mortality if treatment is unsatisfactory. Immunosuppression is the treatment of choice in adults, comparable with allogeneic bone marrow transplant in children. We report two adult patients (both males, aged 59 and 67 years old) who were treated successfully with lymphoglobulin and cyclosporine. The initial response started within 3 months of treatment and was almost complete after 2 years, when cyclosporine was stopped. After three years, both patients have almost normal blood counts, with minor sequels: avascular necrosis of both femoral heads due to the use steroids, that recovered spontaneously in 1 patient and reduced vision due to thrombocytopenic retinal hemorrhages, in the other (Rev Méd Chile 2003; 131: 1439-43).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.131 n.12 20032003-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003001200012es10.4067/S0034-98872003001200012
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Anemia aplastic Cyclosporine thromocytopenia
spellingShingle	Anemia aplastic Cyclosporine thromocytopenia Cabrera C,M Elena Pinto A,Delia Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casos
description	Severe aplastic anemia has an elevated mortality if treatment is unsatisfactory. Immunosuppression is the treatment of choice in adults, comparable with allogeneic bone marrow transplant in children. We report two adult patients (both males, aged 59 and 67 years old) who were treated successfully with lymphoglobulin and cyclosporine. The initial response started within 3 months of treatment and was almost complete after 2 years, when cyclosporine was stopped. After three years, both patients have almost normal blood counts, with minor sequels: avascular necrosis of both femoral heads due to the use steroids, that recovered spontaneously in 1 patient and reduced vision due to thrombocytopenic retinal hemorrhages, in the other (Rev Méd Chile 2003; 131: 1439-43).
author	Cabrera C,M Elena Pinto A,Delia
author_facet	Cabrera C,M Elena Pinto A,Delia
author_sort	Cabrera C,M Elena
title	Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casos
title_short	Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casos
title_full	Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casos
title_fullStr	Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casos
title_full_unstemmed	Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casos
title_sort	anemia aplástica adquirida del adulto: su tratamiento a propósito de dos casos
publisher	Sociedad Médica de Santiago
publishDate	2003
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872003001200012
work_keys_str_mv	AT cabreracmelena anemiaaplasticaadquiridadeladultosutratamientoapropositodedoscasos AT pintoadelia anemiaaplasticaadquiridadeladultosutratamientoapropositodedoscasos
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Anemia aplástica adquirida del adulto: Su tratamiento a propósito de dos casos

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