Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicos

Insulinoma is the most common neuroendocrine tumor. Its clinical manifestations are frequently confounded with neuropsychiatric symptoms, and definitive diagnosis can be delayed for a long time. These tumors are usually small, of less than 2 cm. Thus, their preoperative localization is difficult. We...

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Autores principales:	Martínez O,Darío, Silva Q,Guillermo, Solís O,Iván, Toloza H,Jorge, Benavides C,Carlos, Hamilton S,James, Osorio G,Fernando, Iñiguez V,Germán, Soto I,Néstor
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Angiography Insulinoma Neuroendrocrine tumors
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000100011
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spelling	oai:scielo:S0034-988720040001000112014-08-14Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicosMartínez O,DaríoSilva Q,GuillermoSolís O,IvánToloza H,JorgeBenavides C,CarlosHamilton S,JamesOsorio G,FernandoIñiguez V,GermánSoto I,Néstor Angiography Insulinoma Neuroendrocrine tumors Insulinoma is the most common neuroendocrine tumor. Its clinical manifestations are frequently confounded with neuropsychiatric symptoms, and definitive diagnosis can be delayed for a long time. These tumors are usually small, of less than 2 cm. Thus, their preoperative localization is difficult. We report two patients with a clinical diagnosis of insulinoma, in whom the preoperative imaging study was negative. Both fulfilled diagnostic criteria, with high serum insulin levels in the presence of a blood glucose of less than 45 mg/dl. The imaging study, including abdominal computed tomography and pancreatic endoscopic ultrasonography did not disclose the location of the tumor. A pancreatic angiography with selective stimulation with intra arterial calcium and venous sampling for insulin measurements, was performed in both patients. This test allowed the exact localization of the tumors and their successful excision. A review of other localization diagnostic tests is done (Rev Méd Chile 2004; 132: 71-5).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.1 20042004-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000100011es10.4067/S0034-98872004000100011
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Angiography Insulinoma Neuroendrocrine tumors
spellingShingle	Angiography Insulinoma Neuroendrocrine tumors Martínez O,Darío Silva Q,Guillermo Solís O,Iván Toloza H,Jorge Benavides C,Carlos Hamilton S,James Osorio G,Fernando Iñiguez V,Germán Soto I,Néstor Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicos
description	Insulinoma is the most common neuroendocrine tumor. Its clinical manifestations are frequently confounded with neuropsychiatric symptoms, and definitive diagnosis can be delayed for a long time. These tumors are usually small, of less than 2 cm. Thus, their preoperative localization is difficult. We report two patients with a clinical diagnosis of insulinoma, in whom the preoperative imaging study was negative. Both fulfilled diagnostic criteria, with high serum insulin levels in the presence of a blood glucose of less than 45 mg/dl. The imaging study, including abdominal computed tomography and pancreatic endoscopic ultrasonography did not disclose the location of the tumor. A pancreatic angiography with selective stimulation with intra arterial calcium and venous sampling for insulin measurements, was performed in both patients. This test allowed the exact localization of the tumors and their successful excision. A review of other localization diagnostic tests is done (Rev Méd Chile 2004; 132: 71-5).
author	Martínez O,Darío Silva Q,Guillermo Solís O,Iván Toloza H,Jorge Benavides C,Carlos Hamilton S,James Osorio G,Fernando Iñiguez V,Germán Soto I,Néstor
author_facet	Martínez O,Darío Silva Q,Guillermo Solís O,Iván Toloza H,Jorge Benavides C,Carlos Hamilton S,James Osorio G,Fernando Iñiguez V,Germán Soto I,Néstor
author_sort	Martínez O,Darío
title	Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicos
title_short	Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicos
title_full	Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicos
title_fullStr	Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicos
title_full_unstemmed	Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicos
title_sort	test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: casos clínicos
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000100011
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Test de estimulación intraarterial selectiva con calcio en el diagnóstico de localización de insulinomas: Casos clínicos

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