Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento

Background: From January 2000 to June 2002, the first Chilean registry of unstable angina was carried out, with the participation of 15 hospitals. Aim: To report the clinical and demographic features of 600 patients with unstable angina, their risk profile and prognosis. Material and methods: The in...

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Autores principales:	Corbalán H,Ramón, Nazzal N,Carolina, Eggers R,Germán, Bartolucci J,Jaime, Prieto D,Juan Carlos, Alcaíno I,Milton, Stockins F,Benjamín, Campos P,Pabla, Dapelo A,Alejandro
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Angina, unstable Angioplasty, transluminal, percutaneous coronary Coronary artery bypass Coronary disease
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000200001
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spelling	oai:scielo:S0034-988720040002000012005-11-23Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamientoCorbalán H,RamónNazzal N,CarolinaEggers R,GermánBartolucci J,JaimePrieto D,Juan CarlosAlcaíno I,MiltonStockins F,BenjamínCampos P,PablaDapelo A,Alejandro Angina, unstable Angioplasty, transluminal, percutaneous coronary Coronary artery bypass Coronary disease Background: From January 2000 to June 2002, the first Chilean registry of unstable angina was carried out, with the participation of 15 hospitals. Aim: To report the clinical and demographic features of 600 patients with unstable angina, their risk profile and prognosis. Material and methods: The inclusion criteria for this prospective registry were a history of recent onset of chest pain (<48 hours) or a change in the character of previous angina, associated to ischemic electrocardiographic changes and/or positive markers of myocardial damage. Results: Mean age of the patients was 65 years and 37% were women. Among coronary risk factors, 63% had hypertension, 27% had diabetes, 52% had dyslipidemia, 31% smoked and 21% had a family history of atherosclerosis. On admission 94% of patients had chest pain, associated to ST segment depression in 44%, negative T waves in 28% and positive markers of myocardial damage in 30%. Fifty seven percent received intravenous nitroglycerin, 47% received oral nitrates, 69% beta blockers and 15%, calcium antagonists. Antithrombotic therapy included aspirin in 96%, heparin in 74%, ticlodipine or clopidogrel in 19% and IIb/IIIa inhibitors in 12%. A coronary angiogram was performed in 52%, angioplasty in 25% and coronary bypass surgery in 13%. Hospital mortality was 2.6%. The incidence of new ischemic events was: myocardial infarction in 2.8% recurrent ischemia in 9.5% and refractory ischemia in 2%. The incidence of adverse events increased according to a higher risk profile. Conclusions: The demographic and clinical features, treatment and mortality of these patients are similar to those reported in international registries, with a low mortality rate (Rev Méd Chile 2004; 132: 135-43)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.2 20042004-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000200001es10.4067/S0034-98872004000200001
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Angina, unstable Angioplasty, transluminal, percutaneous coronary Coronary artery bypass Coronary disease
spellingShingle	Angina, unstable Angioplasty, transluminal, percutaneous coronary Coronary artery bypass Coronary disease Corbalán H,Ramón Nazzal N,Carolina Eggers R,Germán Bartolucci J,Jaime Prieto D,Juan Carlos Alcaíno I,Milton Stockins F,Benjamín Campos P,Pabla Dapelo A,Alejandro Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento
description	Background: From January 2000 to June 2002, the first Chilean registry of unstable angina was carried out, with the participation of 15 hospitals. Aim: To report the clinical and demographic features of 600 patients with unstable angina, their risk profile and prognosis. Material and methods: The inclusion criteria for this prospective registry were a history of recent onset of chest pain (<48 hours) or a change in the character of previous angina, associated to ischemic electrocardiographic changes and/or positive markers of myocardial damage. Results: Mean age of the patients was 65 years and 37% were women. Among coronary risk factors, 63% had hypertension, 27% had diabetes, 52% had dyslipidemia, 31% smoked and 21% had a family history of atherosclerosis. On admission 94% of patients had chest pain, associated to ST segment depression in 44%, negative T waves in 28% and positive markers of myocardial damage in 30%. Fifty seven percent received intravenous nitroglycerin, 47% received oral nitrates, 69% beta blockers and 15%, calcium antagonists. Antithrombotic therapy included aspirin in 96%, heparin in 74%, ticlodipine or clopidogrel in 19% and IIb/IIIa inhibitors in 12%. A coronary angiogram was performed in 52%, angioplasty in 25% and coronary bypass surgery in 13%. Hospital mortality was 2.6%. The incidence of new ischemic events was: myocardial infarction in 2.8% recurrent ischemia in 9.5% and refractory ischemia in 2%. The incidence of adverse events increased according to a higher risk profile. Conclusions: The demographic and clinical features, treatment and mortality of these patients are similar to those reported in international registries, with a low mortality rate (Rev Méd Chile 2004; 132: 135-43)
author	Corbalán H,Ramón Nazzal N,Carolina Eggers R,Germán Bartolucci J,Jaime Prieto D,Juan Carlos Alcaíno I,Milton Stockins F,Benjamín Campos P,Pabla Dapelo A,Alejandro
author_facet	Corbalán H,Ramón Nazzal N,Carolina Eggers R,Germán Bartolucci J,Jaime Prieto D,Juan Carlos Alcaíno I,Milton Stockins F,Benjamín Campos P,Pabla Dapelo A,Alejandro
author_sort	Corbalán H,Ramón
title	Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento
title_short	Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento
title_full	Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento
title_fullStr	Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento
title_full_unstemmed	Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento
title_sort	resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000200001
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Resultados del primer registro chileno de angina inestable: características clínicas, perfil de riesgo y tratamiento

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