Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de Chile

Background: The easy access and inappropriate use of antimicrobials led to selection and spread of resistant microorganisms strains. It is imperative to search for new and more effective antimicrobials. One strategy is the screening of metabolites produced by microorganisms found in the environment....

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Autores principales:	Leiva P,Sergio, Yáñez S,Marisa, Zaror C,Luis, Rodríguez S,Héctor, García-Quintana,Héctor
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Actinomycetaceae Antibiotics, antifungal Antibiotics, combined Streptomyces
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000200003
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spelling	oai:scielo:S0034-988720040002000032005-11-23Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de ChileLeiva P,SergioYáñez S,MarisaZaror C,LuisRodríguez S,HéctorGarcía-Quintana,Héctor Actinomycetaceae Antibiotics, antifungal Antibiotics, combined Streptomyces Background: The easy access and inappropriate use of antimicrobials led to selection and spread of resistant microorganisms strains. It is imperative to search for new and more effective antimicrobials. One strategy is the screening of metabolites produced by microorganisms found in the environment. Actinomycetes are a potential source of new drugs. Aim: To isolate actinomycetes from sediments of Chilean rivers and lakes and to screen them for antimicrobial activity against reference bacterial strains and pathogenic fungi. Material and Methods: Actinomycetes were isolated from sediment samples, using casein-starch agar. The antimicrobial activity against 3 bacterial species and 7 fungal species was tested using the disc diffusion method. For the extraction of active metabolites, culture broths of antagonistic actinomycetes were extracted with organic solvents followed by testing the antibiotic activity. Results: A total of 62 strains of actinomycetes were isolated, mainly Streptomyces sp (83.9%). Thirty six strains (58.1%) showed antimicrobial activity, mainly against Bacillus subtilis and Candida albicans. Some isolates inhibited a wide spectrum of indicator strains, like LRI 4A strain (Streptomyces sp) that inhibited Bacillus subtilis, Candida albicans and 4 filamentous fungi. Conclusions: Lakes and rivers of Southern Chile are an important reservoir of antagonistic actinomycetes, a potential source of new drugs (Rev Méd Chile 2004; 132: 151-9)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.2 20042004-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000200003es10.4067/S0034-98872004000200003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Actinomycetaceae Antibiotics, antifungal Antibiotics, combined Streptomyces
spellingShingle	Actinomycetaceae Antibiotics, antifungal Antibiotics, combined Streptomyces Leiva P,Sergio Yáñez S,Marisa Zaror C,Luis Rodríguez S,Héctor García-Quintana,Héctor Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de Chile
description	Background: The easy access and inappropriate use of antimicrobials led to selection and spread of resistant microorganisms strains. It is imperative to search for new and more effective antimicrobials. One strategy is the screening of metabolites produced by microorganisms found in the environment. Actinomycetes are a potential source of new drugs. Aim: To isolate actinomycetes from sediments of Chilean rivers and lakes and to screen them for antimicrobial activity against reference bacterial strains and pathogenic fungi. Material and Methods: Actinomycetes were isolated from sediment samples, using casein-starch agar. The antimicrobial activity against 3 bacterial species and 7 fungal species was tested using the disc diffusion method. For the extraction of active metabolites, culture broths of antagonistic actinomycetes were extracted with organic solvents followed by testing the antibiotic activity. Results: A total of 62 strains of actinomycetes were isolated, mainly Streptomyces sp (83.9%). Thirty six strains (58.1%) showed antimicrobial activity, mainly against Bacillus subtilis and Candida albicans. Some isolates inhibited a wide spectrum of indicator strains, like LRI 4A strain (Streptomyces sp) that inhibited Bacillus subtilis, Candida albicans and 4 filamentous fungi. Conclusions: Lakes and rivers of Southern Chile are an important reservoir of antagonistic actinomycetes, a potential source of new drugs (Rev Méd Chile 2004; 132: 151-9)
author	Leiva P,Sergio Yáñez S,Marisa Zaror C,Luis Rodríguez S,Héctor García-Quintana,Héctor
author_facet	Leiva P,Sergio Yáñez S,Marisa Zaror C,Luis Rodríguez S,Héctor García-Quintana,Héctor
author_sort	Leiva P,Sergio
title	Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de Chile
title_short	Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de Chile
title_full	Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de Chile
title_fullStr	Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de Chile
title_full_unstemmed	Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de Chile
title_sort	actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de chile
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000200003
work_keys_str_mv	AT leivapsergio actividadantimicrobianadeactinomycetesaisladosdesdeambientesacuaticosdelsurdechile AT yanezsmarisa actividadantimicrobianadeactinomycetesaisladosdesdeambientesacuaticosdelsurdechile AT zarorcluis actividadantimicrobianadeactinomycetesaisladosdesdeambientesacuaticosdelsurdechile AT rodriguezshector actividadantimicrobianadeactinomycetesaisladosdesdeambientesacuaticosdelsurdechile AT garciaquintanahector actividadantimicrobianadeactinomycetesaisladosdesdeambientesacuaticosdelsurdechile
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Actividad antimicrobiana de actinomycetes aislados desde ambientes acuáticos del sur de Chile

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