Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientes

Background: Plasmapheresis can be useful in myasthenia gravis, Guillain Barré syndrome and chronic demyelinating inflamatory polyradiculoneuritis. Aim: To report our experience with plasmapheresis in patients with neurological diseases. Material and methods: Retrospective review of plasmapheresis pr...

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Autores principales:	Nogales-Gaete,Jorge, Valenzuela T,Daniel, Liendo P,Federico, Vidal A,Pamela, Gil F,Gloria, Sáez M,David
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Myasthenia Gravis Plasma exchange Plasmapheresis Polyradiculoneuritis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300003
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spelling	oai:scielo:S0034-988720040003000032004-12-13Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientesNogales-Gaete,JorgeValenzuela T,DanielLiendo P,FedericoVidal A,PamelaGil F,GloriaSáez M,David Myasthenia Gravis Plasma exchange Plasmapheresis Polyradiculoneuritis Background: Plasmapheresis can be useful in myasthenia gravis, Guillain Barré syndrome and chronic demyelinating inflamatory polyradiculoneuritis. Aim: To report our experience with plasmapheresis in patients with neurological diseases. Material and methods: Retrospective review of plasmapheresis procedures done between 1995 and 2001, in a public hospital. Indications criteria, clinical results and technical yield were analyzed. Results: One hundred fifty nine procedures were reviewed. One hundred forty (88%) were indicated for neurological diseases (44% for Guillain Barré syndrome and 29% for myasthenia gravis). Clinical improvement or eventual complications were avoided in 70% of patients with Guillain Barré syndrome and 100% of patients with myasthenia gravis. Hypotension in 10% and paresthesias in 7% were observed. All complications were successfully controlled with crystalloid or fresh plasma infusions or citrate management. In 11 cases, the procedure was interrupted due to obstruction of the venous access, that was peripheral in eight of these. The most common difficulties of the procedure were delay in performing it in 50% of patients and insufficient exchange volumes in 30%. Conclusions: Plasmapheresis was safe and useful in patients with myasthenia gravis and Guillain Barré syndrome. The drawbacks of the procedure are its costs and requirement of special equipment (Rev Méd Chile 2004; 132: 295-8).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.3 20042004-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300003es10.4067/S0034-98872004000300003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Myasthenia Gravis Plasma exchange Plasmapheresis Polyradiculoneuritis
spellingShingle	Myasthenia Gravis Plasma exchange Plasmapheresis Polyradiculoneuritis Nogales-Gaete,Jorge Valenzuela T,Daniel Liendo P,Federico Vidal A,Pamela Gil F,Gloria Sáez M,David Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientes
description	Background: Plasmapheresis can be useful in myasthenia gravis, Guillain Barré syndrome and chronic demyelinating inflamatory polyradiculoneuritis. Aim: To report our experience with plasmapheresis in patients with neurological diseases. Material and methods: Retrospective review of plasmapheresis procedures done between 1995 and 2001, in a public hospital. Indications criteria, clinical results and technical yield were analyzed. Results: One hundred fifty nine procedures were reviewed. One hundred forty (88%) were indicated for neurological diseases (44% for Guillain Barré syndrome and 29% for myasthenia gravis). Clinical improvement or eventual complications were avoided in 70% of patients with Guillain Barré syndrome and 100% of patients with myasthenia gravis. Hypotension in 10% and paresthesias in 7% were observed. All complications were successfully controlled with crystalloid or fresh plasma infusions or citrate management. In 11 cases, the procedure was interrupted due to obstruction of the venous access, that was peripheral in eight of these. The most common difficulties of the procedure were delay in performing it in 50% of patients and insufficient exchange volumes in 30%. Conclusions: Plasmapheresis was safe and useful in patients with myasthenia gravis and Guillain Barré syndrome. The drawbacks of the procedure are its costs and requirement of special equipment (Rev Méd Chile 2004; 132: 295-8).
author	Nogales-Gaete,Jorge Valenzuela T,Daniel Liendo P,Federico Vidal A,Pamela Gil F,Gloria Sáez M,David
author_facet	Nogales-Gaete,Jorge Valenzuela T,Daniel Liendo P,Federico Vidal A,Pamela Gil F,Gloria Sáez M,David
author_sort	Nogales-Gaete,Jorge
title	Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientes
title_short	Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientes
title_full	Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientes
title_fullStr	Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientes
title_full_unstemmed	Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientes
title_sort	plasmaféresis indicada por enfermedad neurológica: experiencia de 140 procedimientos en 47 pacientes
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300003
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Plasmaféresis indicada por enfermedad neurológica: Experiencia de 140 procedimientos en 47 pacientes

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