Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad

Background : Influenza-A (IA) occurs every winter, is mostly observed among outpatients. Aim: To describe the clinical and epidemiological characteristics of cases that required hospital admission during an outbreak in Chile in 1999. Patients and methods: Adults subjects, with Influenza A confirmed...

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Autores principales:	Rabagliati B,Ricardo, Benítez G,Rosana, Fernández M,Alicia, Gaete G,Pablo, Guzmán D,Ana María, García C,Patricia, Ferrés G,Marcela, Pérez C,Carlos, Labarca L,Jaime
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Influenza A virus, human Pneumonia, viral Respiratory distress syndrome, adult)
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300006
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spelling	oai:scielo:S0034-988720040003000062004-12-13Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidadRabagliati B,RicardoBenítez G,RosanaFernández M,AliciaGaete G,PabloGuzmán D,Ana MaríaGarcía C,PatriciaFerrés G,MarcelaPérez C,CarlosLabarca L,Jaime Influenza A virus, human Pneumonia, viral Respiratory distress syndrome, adult) Background : Influenza-A (IA) occurs every winter, is mostly observed among outpatients. Aim: To describe the clinical and epidemiological characteristics of cases that required hospital admission during an outbreak in Chile in 1999. Patients and methods: Adults subjects, with Influenza A confirmed by antigen detection test, hospitalized in the clinical hospital of the «Hospital Clínico de la Universidad Católica de Chile» between May and June, with fever or respiratory symptoms were studied. A special record was designed to register clinical, microbiological and therapeutic data. Results: Fifty five cases, 26 males, aged 15 to 91 years, were studied. Eighty four percent had chronic concomitant diseases and 9.1% were immunosuppressed. Clinical findings were fever in 87.3%, asthenia in 83.6%, cough in 93.6%, abnormal pulmonary signs in 69%, an elevated C-reactive protein (mean value of 11.6 ± 7.1 mg/dL) and acute respiratory insufficiency in 54.5%. Cases were isolated in cohort or individual rooms and 38.2% were admitted to intensive or intermediate care units. Amantadine was prescribed to 52 patients and was well tolerated. Thirty three percent of cases developed pneumonia. These subjects were older, had more dyspnea and respiratory insufficiency than patients without pneumonia. Conclusions: IA should be borne in mind when dealing with hospitalized adults, during epidemic outbreaks in the community. The clinical picture can resemble a serious bacterial infection. An early diagnosis allows the use of specific treatments, to decrease the risk of nosocomial spread and to avoid unnecessary use of antibiotics (Rev Méd Chile 2004; 132: 317-24).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.3 20042004-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300006es10.4067/S0034-98872004000300006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Influenza A virus, human Pneumonia, viral Respiratory distress syndrome, adult)
spellingShingle	Influenza A virus, human Pneumonia, viral Respiratory distress syndrome, adult) Rabagliati B,Ricardo Benítez G,Rosana Fernández M,Alicia Gaete G,Pablo Guzmán D,Ana María García C,Patricia Ferrés G,Marcela Pérez C,Carlos Labarca L,Jaime Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad
description	Background : Influenza-A (IA) occurs every winter, is mostly observed among outpatients. Aim: To describe the clinical and epidemiological characteristics of cases that required hospital admission during an outbreak in Chile in 1999. Patients and methods: Adults subjects, with Influenza A confirmed by antigen detection test, hospitalized in the clinical hospital of the «Hospital Clínico de la Universidad Católica de Chile» between May and June, with fever or respiratory symptoms were studied. A special record was designed to register clinical, microbiological and therapeutic data. Results: Fifty five cases, 26 males, aged 15 to 91 years, were studied. Eighty four percent had chronic concomitant diseases and 9.1% were immunosuppressed. Clinical findings were fever in 87.3%, asthenia in 83.6%, cough in 93.6%, abnormal pulmonary signs in 69%, an elevated C-reactive protein (mean value of 11.6 ± 7.1 mg/dL) and acute respiratory insufficiency in 54.5%. Cases were isolated in cohort or individual rooms and 38.2% were admitted to intensive or intermediate care units. Amantadine was prescribed to 52 patients and was well tolerated. Thirty three percent of cases developed pneumonia. These subjects were older, had more dyspnea and respiratory insufficiency than patients without pneumonia. Conclusions: IA should be borne in mind when dealing with hospitalized adults, during epidemic outbreaks in the community. The clinical picture can resemble a serious bacterial infection. An early diagnosis allows the use of specific treatments, to decrease the risk of nosocomial spread and to avoid unnecessary use of antibiotics (Rev Méd Chile 2004; 132: 317-24).
author	Rabagliati B,Ricardo Benítez G,Rosana Fernández M,Alicia Gaete G,Pablo Guzmán D,Ana María García C,Patricia Ferrés G,Marcela Pérez C,Carlos Labarca L,Jaime
author_facet	Rabagliati B,Ricardo Benítez G,Rosana Fernández M,Alicia Gaete G,Pablo Guzmán D,Ana María García C,Patricia Ferrés G,Marcela Pérez C,Carlos Labarca L,Jaime
author_sort	Rabagliati B,Ricardo
title	Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad
title_short	Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad
title_full	Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad
title_fullStr	Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad
title_full_unstemmed	Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad
title_sort	reconocimiento de influenza-a como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300006
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Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad

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