Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramiento

Locked-in syndrome is a dramatic clinical condition, the patient is awake, can listen and breath, but is unable to move any muscle, conserving only the vertical eye movements. The most common cause of locked-in syndrome is the thrombosis of the basilar artery and commonly leads to death, frequently...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mellado T,Patricio, Sandoval R,Patricio, Tevah C,José, Huete L,Isidro, Castillo F,Luis
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Locked-in syndrome Plasminogen activators Thrombolytic therapy Vertebrobasilar insufficiency
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300012
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872004000300012
record_format	dspace
spelling	oai:scielo:S0034-988720040003000122004-12-13Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramientoMellado T,PatricioSandoval R,PatricioTevah C,JoséHuete L,IsidroCastillo F,Luis Locked-in syndrome Plasminogen activators Thrombolytic therapy Vertebrobasilar insufficiency Locked-in syndrome is a dramatic clinical condition, the patient is awake, can listen and breath, but is unable to move any muscle, conserving only the vertical eye movements. The most common cause of locked-in syndrome is the thrombosis of the basilar artery and commonly leads to death, frequently due to pneumonia. Intravenous and intra arterial thrombolysis have been used successfully in a selective group of patients with ischemic stroke. There is only one report of two patients with locked-in syndrome who were treated successfully with intra arterial thrombolysis. Other authors, based in their experiences, do not recommend this treatment. We report two female patients aged 63 and 26 years, with Locked-in syndrome due to a basilar thrombosis who were treated successfully with intra arterial thrombolysis using ecombinant tissue plasminogen activator (r-TPA). The lapses between the onset of the symptoms and thrombolysis were 5 and 8 hours respectively. A complete recanalization was obtained in both patients during the thrombolysis. One year after, the first patient has only a moderate ataxia, walking with assistance and the other has a normal neurological examination (Rev Méd Chile 2004; 132: 357-60 ).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.3 20042004-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300012es10.4067/S0034-98872004000300012
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Locked-in syndrome Plasminogen activators Thrombolytic therapy Vertebrobasilar insufficiency
spellingShingle	Locked-in syndrome Plasminogen activators Thrombolytic therapy Vertebrobasilar insufficiency Mellado T,Patricio Sandoval R,Patricio Tevah C,José Huete L,Isidro Castillo F,Luis Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramiento
description	Locked-in syndrome is a dramatic clinical condition, the patient is awake, can listen and breath, but is unable to move any muscle, conserving only the vertical eye movements. The most common cause of locked-in syndrome is the thrombosis of the basilar artery and commonly leads to death, frequently due to pneumonia. Intravenous and intra arterial thrombolysis have been used successfully in a selective group of patients with ischemic stroke. There is only one report of two patients with locked-in syndrome who were treated successfully with intra arterial thrombolysis. Other authors, based in their experiences, do not recommend this treatment. We report two female patients aged 63 and 26 years, with Locked-in syndrome due to a basilar thrombosis who were treated successfully with intra arterial thrombolysis using ecombinant tissue plasminogen activator (r-TPA). The lapses between the onset of the symptoms and thrombolysis were 5 and 8 hours respectively. A complete recanalization was obtained in both patients during the thrombolysis. One year after, the first patient has only a moderate ataxia, walking with assistance and the other has a normal neurological examination (Rev Méd Chile 2004; 132: 357-60 ).
author	Mellado T,Patricio Sandoval R,Patricio Tevah C,José Huete L,Isidro Castillo F,Luis
author_facet	Mellado T,Patricio Sandoval R,Patricio Tevah C,José Huete L,Isidro Castillo F,Luis
author_sort	Mellado T,Patricio
title	Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramiento
title_short	Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramiento
title_full	Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramiento
title_fullStr	Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramiento
title_full_unstemmed	Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramiento
title_sort	trombolisis intraarterial en trombosis de la arteria basilar: recuperación de dos pacientes con síndrome de enclaustramiento
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000300012
work_keys_str_mv	AT melladotpatricio trombolisisintraarterialentrombosisdelaarteriabasilarrecuperaciondedospacientesconsindromedeenclaustramiento AT sandovalrpatricio trombolisisintraarterialentrombosisdelaarteriabasilarrecuperaciondedospacientesconsindromedeenclaustramiento AT tevahcjose trombolisisintraarterialentrombosisdelaarteriabasilarrecuperaciondedospacientesconsindromedeenclaustramiento AT huetelisidro trombolisisintraarterialentrombosisdelaarteriabasilarrecuperaciondedospacientesconsindromedeenclaustramiento AT castillofluis trombolisisintraarterialentrombosisdelaarteriabasilarrecuperaciondedospacientesconsindromedeenclaustramiento
_version_	1718436141287342080

Trombolisis intraarterial en trombosis de la arteria basilar: Recuperación de dos pacientes con síndrome de enclaustramiento

Ejemplares similares