Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos

Background: Endothelial dysfunction is an important pathogenetic mechanism in the development of atherosclerosis. Aim: To evaluate endothelial function in Chilean children and adult subjects and to provide normal values of flow mediated dilatation (FMD) in the Chilean population. Subjects and Method...

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Autores principales:	Germain A,Alfredo M, Irribarra P,Verónica, Valdés S,Gloria, Romanik F,Mary Carmen, Leighton P,Federico, Mardones S,Francisco, Cuevas M,Ada
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Atherosclerosis Endothelium Vascular ultrasonography
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000400005
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spelling	oai:scielo:S0034-988720040004000052004-12-13Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenosGermain A,Alfredo MIrribarra P,VerónicaValdés S,GloriaRomanik F,Mary CarmenLeighton P,FedericoMardones S,FranciscoCuevas M,Ada Atherosclerosis Endothelium Vascular ultrasonography Background: Endothelial dysfunction is an important pathogenetic mechanism in the development of atherosclerosis. Aim: To evaluate endothelial function in Chilean children and adult subjects and to provide normal values of flow mediated dilatation (FMD) in the Chilean population. Subjects and Methods: Flow mediated dilation of the brachial artery was measured by high resolution ultrasonography in healthy children (n=32) and adults (n=69) of both gender, in a group of 8 healthy women during 4 periods of pregnancy and late postpartum, and in 22 men and women with a history of stroke or coronary heart disease. Results: FMD in boys and girls was 9.9±3.6 and 10.0±4.2% respectively (NS). The figures for young women and young men were 11.3±3.8 and 8.6±3.9, respectively (p=0.02); for postmenopausal women and older men, 5.5±6.6 and 7.6±6.7 respectively (NS). During normal pregnancy and postpartum there were no significant changes in FMD. Patients with cardiovascular disease had a FMD of 0.3±5.2%, (p <0.001, with other groups). Conclusions: The present study provides values of FMD in healthy Chilean subjects of different ages, and in patients with coronary heart disease (Rev Méd Chile 2004; 132: 437-44)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.4 20042004-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000400005es10.4067/S0034-98872004000400005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Atherosclerosis Endothelium Vascular ultrasonography
spellingShingle	Atherosclerosis Endothelium Vascular ultrasonography Germain A,Alfredo M Irribarra P,Verónica Valdés S,Gloria Romanik F,Mary Carmen Leighton P,Federico Mardones S,Francisco Cuevas M,Ada Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos
description	Background: Endothelial dysfunction is an important pathogenetic mechanism in the development of atherosclerosis. Aim: To evaluate endothelial function in Chilean children and adult subjects and to provide normal values of flow mediated dilatation (FMD) in the Chilean population. Subjects and Methods: Flow mediated dilation of the brachial artery was measured by high resolution ultrasonography in healthy children (n=32) and adults (n=69) of both gender, in a group of 8 healthy women during 4 periods of pregnancy and late postpartum, and in 22 men and women with a history of stroke or coronary heart disease. Results: FMD in boys and girls was 9.9±3.6 and 10.0±4.2% respectively (NS). The figures for young women and young men were 11.3±3.8 and 8.6±3.9, respectively (p=0.02); for postmenopausal women and older men, 5.5±6.6 and 7.6±6.7 respectively (NS). During normal pregnancy and postpartum there were no significant changes in FMD. Patients with cardiovascular disease had a FMD of 0.3±5.2%, (p <0.001, with other groups). Conclusions: The present study provides values of FMD in healthy Chilean subjects of different ages, and in patients with coronary heart disease (Rev Méd Chile 2004; 132: 437-44)
author	Germain A,Alfredo M Irribarra P,Verónica Valdés S,Gloria Romanik F,Mary Carmen Leighton P,Federico Mardones S,Francisco Cuevas M,Ada
author_facet	Germain A,Alfredo M Irribarra P,Verónica Valdés S,Gloria Romanik F,Mary Carmen Leighton P,Federico Mardones S,Francisco Cuevas M,Ada
author_sort	Germain A,Alfredo M
title	Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos
title_short	Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos
title_full	Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos
title_fullStr	Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos
title_full_unstemmed	Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos
title_sort	evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000400005
work_keys_str_mv	AT germainaalfredom evaluacionultrasonograficadelafuncionendotelialenninosyadultoschilenos AT irribarrapveronica evaluacionultrasonograficadelafuncionendotelialenninosyadultoschilenos AT valdessgloria evaluacionultrasonograficadelafuncionendotelialenninosyadultoschilenos AT romanikfmarycarmen evaluacionultrasonograficadelafuncionendotelialenninosyadultoschilenos AT leightonpfederico evaluacionultrasonograficadelafuncionendotelialenninosyadultoschilenos AT mardonessfrancisco evaluacionultrasonograficadelafuncionendotelialenninosyadultoschilenos AT cuevasmada evaluacionultrasonograficadelafuncionendotelialenninosyadultoschilenos
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Evaluación ultrasonográfica de la función endotelial en niños y adultos chilenos

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