Síndrome de Poems: Caso clínico

Poems syndrome (polyneuropathy, organomegaly, endocrine abnormality, M-protein, plasma cell dyscrasia, and skin lesions) is a plasma cell dyscrasia whose pathogenesis is unknown. We report a 60 years old woman that presented a tetraparesis caused by a sensitive motor polyneuropathy. The subsequent w...

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Detalles Bibliográficos
Autores principales: Horta H,Pabla, Quevedo L,Iván
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2004
Materias:
IgA
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000400011
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Sumario:Poems syndrome (polyneuropathy, organomegaly, endocrine abnormality, M-protein, plasma cell dyscrasia, and skin lesions) is a plasma cell dyscrasia whose pathogenesis is unknown. We report a 60 years old woman that presented a tetraparesis caused by a sensitive motor polyneuropathy. The subsequent work up revealed an IgA type monoclonal gammopathy, hepatomegaly, hyperestrogenism, primary adrenal failure, hypothyroidism, hyperpigmentation and erythematous lesions in the skin and ankle edema. The patient is being treated with prednisone 0.5 mg/kg and levothyroxine 100 µg/day, with partial remission of her symptoms (Rev Méd Chile 2004; 132: 485-8)