Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos
Bacteria have developed sophisticated and successful genetic mechanisms to evade the action of antimicrobials. Bacterial multiresistance has caused serious problems in the treatment of nosocomial infections. Integrons and gene cassettes are considered the main genetic elements in the evolution of pl...
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Lenguaje: | Spanish / Castilian |
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Sociedad Médica de Santiago
2004
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oai:scielo:S0034-988720040005000132005-11-18Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianosGonzález R,GerardoMella M,SergioZemelman Z,RaúlBello T,HeliaDomínguez Y,Mariana Gene cassettes Gram-Negative bacterial infectious integrons Microbial sensitivity tests Bacteria have developed sophisticated and successful genetic mechanisms to evade the action of antimicrobials. Bacterial multiresistance has caused serious problems in the treatment of nosocomial infections. Integrons and gene cassettes are considered the main genetic elements in the evolution of plasmids and transposons that actively participate in the mobilization of genes, codifying different bacterial resistance mechanisms. This article reviews the historical and structural aspects of integrons and resistance gene cassettes and the presence of these structures in Gram negative bacteria isolated from Chilean hospitals in the last ten years (Rev Méd Chile 2004; 132: 619-26).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.5 20042004-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000500013es10.4067/S0034-98872004000500013 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Gene cassettes Gram-Negative bacterial infectious integrons Microbial sensitivity tests |
spellingShingle |
Gene cassettes Gram-Negative bacterial infectious integrons Microbial sensitivity tests González R,Gerardo Mella M,Sergio Zemelman Z,Raúl Bello T,Helia Domínguez Y,Mariana Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos |
description |
Bacteria have developed sophisticated and successful genetic mechanisms to evade the action of antimicrobials. Bacterial multiresistance has caused serious problems in the treatment of nosocomial infections. Integrons and gene cassettes are considered the main genetic elements in the evolution of plasmids and transposons that actively participate in the mobilization of genes, codifying different bacterial resistance mechanisms. This article reviews the historical and structural aspects of integrons and resistance gene cassettes and the presence of these structures in Gram negative bacteria isolated from Chilean hospitals in the last ten years (Rev Méd Chile 2004; 132: 619-26). |
author |
González R,Gerardo Mella M,Sergio Zemelman Z,Raúl Bello T,Helia Domínguez Y,Mariana |
author_facet |
González R,Gerardo Mella M,Sergio Zemelman Z,Raúl Bello T,Helia Domínguez Y,Mariana |
author_sort |
González R,Gerardo |
title |
Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos |
title_short |
Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos |
title_full |
Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos |
title_fullStr |
Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos |
title_full_unstemmed |
Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos |
title_sort |
integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos |
publisher |
Sociedad Médica de Santiago |
publishDate |
2004 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000500013 |
work_keys_str_mv |
AT gonzalezrgerardo integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos AT mellamsergio integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos AT zemelmanzraul integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos AT bellothelia integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos AT dominguezymariana integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos |
_version_ |
1718436150758080512 |