Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos

Bacteria have developed sophisticated and successful genetic mechanisms to evade the action of antimicrobials. Bacterial multiresistance has caused serious problems in the treatment of nosocomial infections. Integrons and gene cassettes are considered the main genetic elements in the evolution of pl...

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Autores principales: González R,Gerardo, Mella M,Sergio, Zemelman Z,Raúl, Bello T,Helia, Domínguez Y,Mariana
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2004
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000500013
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spelling oai:scielo:S0034-988720040005000132005-11-18Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianosGonzález R,GerardoMella M,SergioZemelman Z,RaúlBello T,HeliaDomínguez Y,Mariana Gene cassettes Gram-Negative bacterial infectious integrons Microbial sensitivity tests Bacteria have developed sophisticated and successful genetic mechanisms to evade the action of antimicrobials. Bacterial multiresistance has caused serious problems in the treatment of nosocomial infections. Integrons and gene cassettes are considered the main genetic elements in the evolution of plasmids and transposons that actively participate in the mobilization of genes, codifying different bacterial resistance mechanisms. This article reviews the historical and structural aspects of integrons and resistance gene cassettes and the presence of these structures in Gram negative bacteria isolated from Chilean hospitals in the last ten years (Rev Méd Chile 2004; 132: 619-26).info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.5 20042004-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000500013es10.4067/S0034-98872004000500013
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Gene cassettes
Gram-Negative bacterial infectious
integrons
Microbial sensitivity tests
spellingShingle Gene cassettes
Gram-Negative bacterial infectious
integrons
Microbial sensitivity tests
González R,Gerardo
Mella M,Sergio
Zemelman Z,Raúl
Bello T,Helia
Domínguez Y,Mariana
Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos
description Bacteria have developed sophisticated and successful genetic mechanisms to evade the action of antimicrobials. Bacterial multiresistance has caused serious problems in the treatment of nosocomial infections. Integrons and gene cassettes are considered the main genetic elements in the evolution of plasmids and transposons that actively participate in the mobilization of genes, codifying different bacterial resistance mechanisms. This article reviews the historical and structural aspects of integrons and resistance gene cassettes and the presence of these structures in Gram negative bacteria isolated from Chilean hospitals in the last ten years (Rev Méd Chile 2004; 132: 619-26).
author González R,Gerardo
Mella M,Sergio
Zemelman Z,Raúl
Bello T,Helia
Domínguez Y,Mariana
author_facet González R,Gerardo
Mella M,Sergio
Zemelman Z,Raúl
Bello T,Helia
Domínguez Y,Mariana
author_sort González R,Gerardo
title Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos
title_short Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos
title_full Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos
title_fullStr Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos
title_full_unstemmed Integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos
title_sort integrones y cassettes genéticos de resistencia: estructura y rol frente a los antibacterianos
publisher Sociedad Médica de Santiago
publishDate 2004
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000500013
work_keys_str_mv AT gonzalezrgerardo integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos
AT mellamsergio integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos
AT zemelmanzraul integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos
AT bellothelia integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos
AT dominguezymariana integronesycassettesgeneticosderesistenciaestructurayrolfrentealosantibacterianos
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