Nefritis intersticial aguda y lamotrigina: Report of one case

Acute interstitial nephritis is a mononuclear and sterile inflammation of the renal interstice caused by drugs, infections or immune phenomena. The clinical presentation is characterized by the triad of rash, fever and eosinophilia. We report a 32 years old man, in treatment with lamotrigine for dep...

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Autores principales: Mönckeberg F,Gustavo, Vukusich C,Antonio, Valls G,Gonzalo, Rosenberg G,Helmar
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2004
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000600011
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spelling oai:scielo:S0034-988720040006000112014-08-14Nefritis intersticial aguda y lamotrigina: Report of one caseMönckeberg F,GustavoVukusich C,AntonioValls G,GonzaloRosenberg G,Helmar Antidepressants Drug toxicity Lamotrigine Nephritis interstitial Acute interstitial nephritis is a mononuclear and sterile inflammation of the renal interstice caused by drugs, infections or immune phenomena. The clinical presentation is characterized by the triad of rash, fever and eosinophilia. We report a 32 years old man, in treatment with lamotrigine for depression, admitted to the hospital due to fever, abdominal pain, jaundice, cutaneus rash and malaise. Due to an oliguric renal failure of acute onset, a renal biopsy was done. The pathological study showed a granulomatous acute interstitial nephritis. He was started on hemodialysis and treated with cessation of the drug and corticosteroids, with complete recovery of the renal function (Rev Méd Chile 2004; 132: 742-6)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.6 20042004-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000600011es10.4067/S0034-98872004000600011
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Antidepressants
Drug toxicity
Lamotrigine
Nephritis
interstitial
spellingShingle Antidepressants
Drug toxicity
Lamotrigine
Nephritis
interstitial
Mönckeberg F,Gustavo
Vukusich C,Antonio
Valls G,Gonzalo
Rosenberg G,Helmar
Nefritis intersticial aguda y lamotrigina: Report of one case
description Acute interstitial nephritis is a mononuclear and sterile inflammation of the renal interstice caused by drugs, infections or immune phenomena. The clinical presentation is characterized by the triad of rash, fever and eosinophilia. We report a 32 years old man, in treatment with lamotrigine for depression, admitted to the hospital due to fever, abdominal pain, jaundice, cutaneus rash and malaise. Due to an oliguric renal failure of acute onset, a renal biopsy was done. The pathological study showed a granulomatous acute interstitial nephritis. He was started on hemodialysis and treated with cessation of the drug and corticosteroids, with complete recovery of the renal function (Rev Méd Chile 2004; 132: 742-6)
author Mönckeberg F,Gustavo
Vukusich C,Antonio
Valls G,Gonzalo
Rosenberg G,Helmar
author_facet Mönckeberg F,Gustavo
Vukusich C,Antonio
Valls G,Gonzalo
Rosenberg G,Helmar
author_sort Mönckeberg F,Gustavo
title Nefritis intersticial aguda y lamotrigina: Report of one case
title_short Nefritis intersticial aguda y lamotrigina: Report of one case
title_full Nefritis intersticial aguda y lamotrigina: Report of one case
title_fullStr Nefritis intersticial aguda y lamotrigina: Report of one case
title_full_unstemmed Nefritis intersticial aguda y lamotrigina: Report of one case
title_sort nefritis intersticial aguda y lamotrigina: report of one case
publisher Sociedad Médica de Santiago
publishDate 2004
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000600011
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AT vallsggonzalo nefritisintersticialagudaylamotriginareportofonecase
AT rosenbergghelmar nefritisintersticialagudaylamotriginareportofonecase
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