Alteraciones motoras gastrointestinales en la enfermedad de Chagas

Serum antibodies against Trypanosoma Cruzi have been observed in 19% of the Chilean population. Marked differences in organ involvement have been reported in patients with Chagas disease. Chagas disease is rarely an aetiological factor for achalasia in Chile, which is different from reports in other...

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Autores principales: Madrid S,Ana María, Quera P,Rodrigo, Defilippi C,Carlos, Defilippi G,Claudia, Gil L,Luis C, Sapunar P,Jorge, Henríquez D,Ana
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2004
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000800005
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spelling oai:scielo:S0034-988720040008000052014-08-14Alteraciones motoras gastrointestinales en la enfermedad de ChagasMadrid S,Ana MaríaQuera P,RodrigoDefilippi C,CarlosDefilippi G,ClaudiaGil L,Luis CSapunar P,JorgeHenríquez D,Ana Chagas disease Gastrointestinal motility Electrogastrography Serum antibodies against Trypanosoma Cruzi have been observed in 19% of the Chilean population. Marked differences in organ involvement have been reported in patients with Chagas disease. Chagas disease is rarely an aetiological factor for achalasia in Chile, which is different from reports in other countries of South America. In contrast, a high incidence of megacolon among these patients have been reported. Aim: To study the incidence of gastric and small intestinal motor disorders among these patients and their relationship to esophageal and colon motility disorders. Patients and Methods: We studied 18 patients, 12 women (mean age 45 years); with positive antibodies against T Cruzi. Seven had radiological evidence of megacolon and no one had radiological or manometric evidence for achalasia. Non specific motor esophageal abnormalities were found in 11 patients. Nine had an abnormal electrocardiogram, suggesting a myocardial disease. A questionnaire for gastrointestinal symptoms, an electrogastrography and a small intestinal motility study, were performed in each patient. Results: All patients had evidences of abnormalities in at least one segment of the digestive tract. Twelve patients had an abnormal electrogastrographic study, with bradygastria as the most common finding. Nine had an abnormal small intestinal manometry with a myophatic pattern evidenced by a decreased amplitude of contractions (18.5±3 mmHg). Also an increased number of clustered contractions was observed. Conclusions: Gastric dysrhythmias and small intestinal motor abnormalities are frequently associated to non specific esophageal motor disorders and megacolon in patients with Chagas disease (Rev Méd Chile 2004; 132: 939-4)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.8 20042004-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000800005es10.4067/S0034-98872004000800005
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Chagas disease
Gastrointestinal motility
Electrogastrography
spellingShingle Chagas disease
Gastrointestinal motility
Electrogastrography
Madrid S,Ana María
Quera P,Rodrigo
Defilippi C,Carlos
Defilippi G,Claudia
Gil L,Luis C
Sapunar P,Jorge
Henríquez D,Ana
Alteraciones motoras gastrointestinales en la enfermedad de Chagas
description Serum antibodies against Trypanosoma Cruzi have been observed in 19% of the Chilean population. Marked differences in organ involvement have been reported in patients with Chagas disease. Chagas disease is rarely an aetiological factor for achalasia in Chile, which is different from reports in other countries of South America. In contrast, a high incidence of megacolon among these patients have been reported. Aim: To study the incidence of gastric and small intestinal motor disorders among these patients and their relationship to esophageal and colon motility disorders. Patients and Methods: We studied 18 patients, 12 women (mean age 45 years); with positive antibodies against T Cruzi. Seven had radiological evidence of megacolon and no one had radiological or manometric evidence for achalasia. Non specific motor esophageal abnormalities were found in 11 patients. Nine had an abnormal electrocardiogram, suggesting a myocardial disease. A questionnaire for gastrointestinal symptoms, an electrogastrography and a small intestinal motility study, were performed in each patient. Results: All patients had evidences of abnormalities in at least one segment of the digestive tract. Twelve patients had an abnormal electrogastrographic study, with bradygastria as the most common finding. Nine had an abnormal small intestinal manometry with a myophatic pattern evidenced by a decreased amplitude of contractions (18.5±3 mmHg). Also an increased number of clustered contractions was observed. Conclusions: Gastric dysrhythmias and small intestinal motor abnormalities are frequently associated to non specific esophageal motor disorders and megacolon in patients with Chagas disease (Rev Méd Chile 2004; 132: 939-4)
author Madrid S,Ana María
Quera P,Rodrigo
Defilippi C,Carlos
Defilippi G,Claudia
Gil L,Luis C
Sapunar P,Jorge
Henríquez D,Ana
author_facet Madrid S,Ana María
Quera P,Rodrigo
Defilippi C,Carlos
Defilippi G,Claudia
Gil L,Luis C
Sapunar P,Jorge
Henríquez D,Ana
author_sort Madrid S,Ana María
title Alteraciones motoras gastrointestinales en la enfermedad de Chagas
title_short Alteraciones motoras gastrointestinales en la enfermedad de Chagas
title_full Alteraciones motoras gastrointestinales en la enfermedad de Chagas
title_fullStr Alteraciones motoras gastrointestinales en la enfermedad de Chagas
title_full_unstemmed Alteraciones motoras gastrointestinales en la enfermedad de Chagas
title_sort alteraciones motoras gastrointestinales en la enfermedad de chagas
publisher Sociedad Médica de Santiago
publishDate 2004
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004000800005
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