Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región Metropolitana

Background: There is a paucity of information about the epidemiology of acute renal failure in Chile. Aim: To perform a prospective multicentric survey of severe acute renal failure in Chile. Material and methods: All patients admitted to ten hospitals in Metropolitan Santiago, during a period of si...

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Autores principales:	Vukusich C,Antonio, Alvear M,Felipe, Villanueva A,Pablo, González T,Claudio, Olivari P,Francisco, Alvarado A,Nelly, Zehnder B,Carlos
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Kidney failure acute Oliguria Renal dialysis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100003
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spelling	oai:scielo:S0034-988720040011000032005-01-12Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región MetropolitanaVukusich C,AntonioAlvear M,FelipeVillanueva A,PabloGonzález T,ClaudioOlivari P,FranciscoAlvarado A,NellyZehnder B,Carlos Kidney failure acute Oliguria Renal dialysis Background: There is a paucity of information about the epidemiology of acute renal failure in Chile. Aim: To perform a prospective multicentric survey of severe acute renal failure in Chile. Material and methods: All patients admitted to ten hospitals in Metropolitan Santiago, during a period of six months with severe acute renal failure, were studied. The criteria for severity was the requirement of renal replacement therapy. All patients information was gathered in special forms and the type of renal replacement therapy and evolution was registeres. Results: One hundred fourteen patients were studied (65 males, age range 18 to 87 years). The calculated incidence of acute renal failure was 1.03 cases per 1000 hospital discharges. The onset was nosocomial in 79 subjects (69%) and community acquired in the rest. Renal failure was oliguric in 64 cases (56%) and in 60% of patients it had two or more causative factors. Sepsis, isolated or combined with other causes, was present in 51 of patients. Other causes included ischemia in 47%, surgery in 26%, exogenous toxicity in 25%, endocenous toxicity in 11%, acute glomerular damage in 6% and obstructive uropathy in 6%. Cardiac surgery was responsible for 47% of post operative cases of acute renal failure. Intermittent conventional hemodialysis, continuous renal replacement techniques and daily prolonged hemodialysis were used in 66%, 29% and 2% of patients, respectively. Overall mortality was 45% and it was higher in oliguric patients. Gender, age, cause or the type of therapy did not influence survival. Nine percent of surviving patients had some degree of kidney dysfunction at discharge. Conclusions: There is still a great space for prevention of severe acute renal failure in Chile, considering the main etiologies found in this studyinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.11 20042004-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100003es10.4067/S0034-98872004001100003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Kidney failure acute Oliguria Renal dialysis
spellingShingle	Kidney failure acute Oliguria Renal dialysis Vukusich C,Antonio Alvear M,Felipe Villanueva A,Pablo González T,Claudio Olivari P,Francisco Alvarado A,Nelly Zehnder B,Carlos Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región Metropolitana
description	Background: There is a paucity of information about the epidemiology of acute renal failure in Chile. Aim: To perform a prospective multicentric survey of severe acute renal failure in Chile. Material and methods: All patients admitted to ten hospitals in Metropolitan Santiago, during a period of six months with severe acute renal failure, were studied. The criteria for severity was the requirement of renal replacement therapy. All patients information was gathered in special forms and the type of renal replacement therapy and evolution was registeres. Results: One hundred fourteen patients were studied (65 males, age range 18 to 87 years). The calculated incidence of acute renal failure was 1.03 cases per 1000 hospital discharges. The onset was nosocomial in 79 subjects (69%) and community acquired in the rest. Renal failure was oliguric in 64 cases (56%) and in 60% of patients it had two or more causative factors. Sepsis, isolated or combined with other causes, was present in 51 of patients. Other causes included ischemia in 47%, surgery in 26%, exogenous toxicity in 25%, endocenous toxicity in 11%, acute glomerular damage in 6% and obstructive uropathy in 6%. Cardiac surgery was responsible for 47% of post operative cases of acute renal failure. Intermittent conventional hemodialysis, continuous renal replacement techniques and daily prolonged hemodialysis were used in 66%, 29% and 2% of patients, respectively. Overall mortality was 45% and it was higher in oliguric patients. Gender, age, cause or the type of therapy did not influence survival. Nine percent of surviving patients had some degree of kidney dysfunction at discharge. Conclusions: There is still a great space for prevention of severe acute renal failure in Chile, considering the main etiologies found in this study
author	Vukusich C,Antonio Alvear M,Felipe Villanueva A,Pablo González T,Claudio Olivari P,Francisco Alvarado A,Nelly Zehnder B,Carlos
author_facet	Vukusich C,Antonio Alvear M,Felipe Villanueva A,Pablo González T,Claudio Olivari P,Francisco Alvarado A,Nelly Zehnder B,Carlos
author_sort	Vukusich C,Antonio
title	Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región Metropolitana
title_short	Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región Metropolitana
title_full	Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región Metropolitana
title_fullStr	Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región Metropolitana
title_full_unstemmed	Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región Metropolitana
title_sort	epidemiología de la insuficiencia renal aguda grave: un estudio prospectivo multicéntrico en la región metropolitana
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100003
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Epidemiología de la Insuficiencia Renal Aguda grave: Un estudio prospectivo multicéntrico en la Región Metropolitana

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