Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico

Background: Esophageal candidiasis is associated with conditions that cause an immune depression. It is a defining disease for AIDS, is observed in poorly controlled diabetics, in patients with renal or hepatic failure, in patients with cancer and in subjects using medications causing immunosuppress...

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Autores principales:	Cortés M,Claudia, Oksenberg R,Danny, Afani S,Alejandro, Defilippi C,Carlos, Madrid S,Ana María
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Candidiasis esophageal Immunity cellular Immunocompetence
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100008
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spelling	oai:scielo:S0034-988720040011000082005-01-12Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológicoCortés M,ClaudiaOksenberg R,DannyAfani S,AlejandroDefilippi C,CarlosMadrid S,Ana María Candidiasis esophageal Immunity cellular Immunocompetence Background: Esophageal candidiasis is associated with conditions that cause an immune depression. It is a defining disease for AIDS, is observed in poorly controlled diabetics, in patients with renal or hepatic failure, in patients with cancer and in subjects using medications causing immunosuppression or broad spectrum antimicrobials. Aim: To report the features of 10 immunocompetent patients with esophageal candidiasis. Patients and methods: Six males and four females aged between 48 and 82 years, without conditions associated with immunosuppression, in whom an esophageal candidiasis was found on an upper gastrointestinal endoscopy. Delayed skin hypersensitivity to eight antigens, Iymphocyte subpopulations, yeast phagocytosis and neutrophil chemotaxis were measured. Results: Six patients had a low CD4 Iymphocyte count and seven had a low CD8 count. Seven patients were anergic on skin hypersensitivity challenge. Yeast phagocytosis was abnormal in one patient and neutrophil chemotaxis was abnormal in two. Humoral immunity was normal in all subjects. All patients were treated with oral fluconazole in doses of 150 mg/day for 14 days, with complete resolution of candidiasis in all. Conclusions: Patients with esophageal candidiasis, have frequent alterations of cellular immunity, that must be diagnosed and treatedinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.11 20042004-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100008es10.4067/S0034-98872004001100008
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Candidiasis esophageal Immunity cellular Immunocompetence
spellingShingle	Candidiasis esophageal Immunity cellular Immunocompetence Cortés M,Claudia Oksenberg R,Danny Afani S,Alejandro Defilippi C,Carlos Madrid S,Ana María Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico
description	Background: Esophageal candidiasis is associated with conditions that cause an immune depression. It is a defining disease for AIDS, is observed in poorly controlled diabetics, in patients with renal or hepatic failure, in patients with cancer and in subjects using medications causing immunosuppression or broad spectrum antimicrobials. Aim: To report the features of 10 immunocompetent patients with esophageal candidiasis. Patients and methods: Six males and four females aged between 48 and 82 years, without conditions associated with immunosuppression, in whom an esophageal candidiasis was found on an upper gastrointestinal endoscopy. Delayed skin hypersensitivity to eight antigens, Iymphocyte subpopulations, yeast phagocytosis and neutrophil chemotaxis were measured. Results: Six patients had a low CD4 Iymphocyte count and seven had a low CD8 count. Seven patients were anergic on skin hypersensitivity challenge. Yeast phagocytosis was abnormal in one patient and neutrophil chemotaxis was abnormal in two. Humoral immunity was normal in all subjects. All patients were treated with oral fluconazole in doses of 150 mg/day for 14 days, with complete resolution of candidiasis in all. Conclusions: Patients with esophageal candidiasis, have frequent alterations of cellular immunity, that must be diagnosed and treated
author	Cortés M,Claudia Oksenberg R,Danny Afani S,Alejandro Defilippi C,Carlos Madrid S,Ana María
author_facet	Cortés M,Claudia Oksenberg R,Danny Afani S,Alejandro Defilippi C,Carlos Madrid S,Ana María
author_sort	Cortés M,Claudia
title	Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico
title_short	Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico
title_full	Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico
title_fullStr	Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico
title_full_unstemmed	Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico
title_sort	candidiasis esofágica en pacientes inmunocompetentes: estudio clínico e inmunológico
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100008
work_keys_str_mv	AT cortesmclaudia candidiasisesofagicaenpacientesinmunocompetentesestudioclinicoeinmunologico AT oksenbergrdanny candidiasisesofagicaenpacientesinmunocompetentesestudioclinicoeinmunologico AT afanisalejandro candidiasisesofagicaenpacientesinmunocompetentesestudioclinicoeinmunologico AT defilippiccarlos candidiasisesofagicaenpacientesinmunocompetentesestudioclinicoeinmunologico AT madridsanamaria candidiasisesofagicaenpacientesinmunocompetentesestudioclinicoeinmunologico
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Candidiasis esofágica en pacientes inmunocompetentes: Estudio clínico e inmunológico

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