Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínico

We report a 78 year old male with prostatism, that was subjected to a prostate biopsy. The pathological study showed a microvascular lymphocytic infiltration. Four months later, the patients presentd with reduced alertness, cough, dyspnea, fever and elevation of lactic dehydrogenase and erythrocyte...

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Autores principales:	Alfaro L,Jorge, Espinoza N,Arturo, Manríquez A,María, Moyano,Leonor, González G,Néstor, Larrondo L,Milton, Figueroa M,Gastón
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2004
Materias:	Antibodies monoclonal CD20 antigens Lymphoma non-Hodgkin
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100010
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spelling	oai:scielo:S0034-988720040011000102005-01-12Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínicoAlfaro L,JorgeEspinoza N,ArturoManríquez A,MaríaMoyano,LeonorGonzález G,NéstorLarrondo L,MiltonFigueroa M,Gastón Antibodies monoclonal CD20 antigens Lymphoma non-Hodgkin We report a 78 year old male with prostatism, that was subjected to a prostate biopsy. The pathological study showed a microvascular lymphocytic infiltration. Four months later, the patients presentd with reduced alertness, cough, dyspnea, fever and elevation of lactic dehydrogenase and erythrocyte sedimentation rate. Chest and abdominal CAT scans, bone marrow aspirate, protein electrophoresis and prostate specific antigen were normal. A re-evaluation of prostate biopsy showed an intravascular lymphoid infiltration, positive for CD45 and CD20, compatible with the diagnosis of intravascular lymphoma. Chemotherapy was started, but it was not tolerated by the patient and the response was partial. Therefore, treatment with monoclonal antibodies anti CD20 (Rituximab) was started. The tumor had a complete and prolonged (24 months) remission after the treatmentinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.132 n.11 20042004-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100010es10.4067/S0034-98872004001100010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Antibodies monoclonal CD20 antigens Lymphoma non-Hodgkin
spellingShingle	Antibodies monoclonal CD20 antigens Lymphoma non-Hodgkin Alfaro L,Jorge Espinoza N,Arturo Manríquez A,María Moyano,Leonor González G,Néstor Larrondo L,Milton Figueroa M,Gastón Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínico
description	We report a 78 year old male with prostatism, that was subjected to a prostate biopsy. The pathological study showed a microvascular lymphocytic infiltration. Four months later, the patients presentd with reduced alertness, cough, dyspnea, fever and elevation of lactic dehydrogenase and erythrocyte sedimentation rate. Chest and abdominal CAT scans, bone marrow aspirate, protein electrophoresis and prostate specific antigen were normal. A re-evaluation of prostate biopsy showed an intravascular lymphoid infiltration, positive for CD45 and CD20, compatible with the diagnosis of intravascular lymphoma. Chemotherapy was started, but it was not tolerated by the patient and the response was partial. Therefore, treatment with monoclonal antibodies anti CD20 (Rituximab) was started. The tumor had a complete and prolonged (24 months) remission after the treatment
author	Alfaro L,Jorge Espinoza N,Arturo Manríquez A,María Moyano,Leonor González G,Néstor Larrondo L,Milton Figueroa M,Gastón
author_facet	Alfaro L,Jorge Espinoza N,Arturo Manríquez A,María Moyano,Leonor González G,Néstor Larrondo L,Milton Figueroa M,Gastón
author_sort	Alfaro L,Jorge
title	Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínico
title_short	Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínico
title_full	Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínico
title_fullStr	Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínico
title_full_unstemmed	Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínico
title_sort	linfoma intravascular tratado con anticuerpos monoclonales anti cd20: descripción de un caso clínico
publisher	Sociedad Médica de Santiago
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872004001100010
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Linfoma intravascular tratado con anticuerpos monoclonales anti CD20: Descripción de un caso clínico

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