Relación entre la amplificación del oncogén C-erbB-2 y parámetros histológicos con sobrevida libre de enfermedad en pacientes con cáncer de mama
Background:Protooncogene cerbB2 is located in chromosome 17 region q21 and codifies a 185 Kd protein, with tyrosine kinase activity. The amplification of this gene is associated with relapse and lower survival in breast cancer. Overexpression of this gene can be detected by immunohistochemistry (IHC...
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Autores principales: | Rojas-Atencio,Alicia E., Valbuena,Ivonne, Urdaneta,Karelis, Soto-Quintana,Marisol, Álvarez-Nava,Francisco, González,Leonardo, Viloria-Alvarado,María E., Quintero-Bellagamba,Rita |
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Lenguaje: | Spanish / Castilian |
Publicado: |
Sociedad Médica de Santiago
2005
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Materias: | |
Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200001 |
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