Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas

Background: Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis. Aim: To study the presence of thrombophilia in patients with retinal vein thrombosis. Patients and methods: Prospe...

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Autores principales: Traipe C,Leonidas, Conte L,Guillermo, Conte S,Francisco J, Ibáñez L,Santiago, Meza R,Patricio, Rojas U,Basilio, Cuneo V,Marianela, Verdaguer T,Juan
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2005
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200003
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spelling oai:scielo:S0034-988720050002000032005-04-12Determinación de factores trombofílicos en pacientes con trombosis venosas retinianasTraipe C,LeonidasConte L,GuillermoConte S,Francisco JIbáñez L,SantiagoMeza R,PatricioRojas U,BasilioCuneo V,MarianelaVerdaguer T,Juan Activated protein C resistance Antiphospholipid syndrome Retinal vein occlusion Thrombophilia Background: Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis. Aim: To study the presence of thrombophilia in patients with retinal vein thrombosis. Patients and methods: Prospective study of 55 patients aged 22 to 86 years, with retinal vein thrombosis (central or branch). Antithrombin III, coagulant protein C, functional protein S, resistance to activated C protein, homocysteine, prothrombin G20210A gene, lupus anticoagulant and anticardiolipin antibodies were measured in all. Results: Seventeen patients had thrombophilic markers (antiphospholipid syndrome in seven, hyperhomocysteinemia in six and resistance to protein C in three). Of these 17 patients, 53% had high blood pressure, 35% an abnormal serum lipid profile and 23% a personal history of thrombosis. The thrombosis was central in 12 (ischemic in four) and of a branch in five (ischemic in two). Conclusions: Thrombophilic markers must be assessed in patients with retinal vein thrombosis (Rev Méd Chile 2005; 133: 167-74)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.2 20052005-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200003es10.4067/S0034-98872005000200003
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Activated protein C resistance
Antiphospholipid syndrome
Retinal vein occlusion
Thrombophilia
spellingShingle Activated protein C resistance
Antiphospholipid syndrome
Retinal vein occlusion
Thrombophilia
Traipe C,Leonidas
Conte L,Guillermo
Conte S,Francisco J
Ibáñez L,Santiago
Meza R,Patricio
Rojas U,Basilio
Cuneo V,Marianela
Verdaguer T,Juan
Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas
description Background: Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis. Aim: To study the presence of thrombophilia in patients with retinal vein thrombosis. Patients and methods: Prospective study of 55 patients aged 22 to 86 years, with retinal vein thrombosis (central or branch). Antithrombin III, coagulant protein C, functional protein S, resistance to activated C protein, homocysteine, prothrombin G20210A gene, lupus anticoagulant and anticardiolipin antibodies were measured in all. Results: Seventeen patients had thrombophilic markers (antiphospholipid syndrome in seven, hyperhomocysteinemia in six and resistance to protein C in three). Of these 17 patients, 53% had high blood pressure, 35% an abnormal serum lipid profile and 23% a personal history of thrombosis. The thrombosis was central in 12 (ischemic in four) and of a branch in five (ischemic in two). Conclusions: Thrombophilic markers must be assessed in patients with retinal vein thrombosis (Rev Méd Chile 2005; 133: 167-74)
author Traipe C,Leonidas
Conte L,Guillermo
Conte S,Francisco J
Ibáñez L,Santiago
Meza R,Patricio
Rojas U,Basilio
Cuneo V,Marianela
Verdaguer T,Juan
author_facet Traipe C,Leonidas
Conte L,Guillermo
Conte S,Francisco J
Ibáñez L,Santiago
Meza R,Patricio
Rojas U,Basilio
Cuneo V,Marianela
Verdaguer T,Juan
author_sort Traipe C,Leonidas
title Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas
title_short Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas
title_full Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas
title_fullStr Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas
title_full_unstemmed Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas
title_sort determinación de factores trombofílicos en pacientes con trombosis venosas retinianas
publisher Sociedad Médica de Santiago
publishDate 2005
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200003
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