Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas
Background: Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis. Aim: To study the presence of thrombophilia in patients with retinal vein thrombosis. Patients and methods: Prospe...
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Sociedad Médica de Santiago
2005
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oai:scielo:S0034-988720050002000032005-04-12Determinación de factores trombofílicos en pacientes con trombosis venosas retinianasTraipe C,LeonidasConte L,GuillermoConte S,Francisco JIbáñez L,SantiagoMeza R,PatricioRojas U,BasilioCuneo V,MarianelaVerdaguer T,Juan Activated protein C resistance Antiphospholipid syndrome Retinal vein occlusion Thrombophilia Background: Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis. Aim: To study the presence of thrombophilia in patients with retinal vein thrombosis. Patients and methods: Prospective study of 55 patients aged 22 to 86 years, with retinal vein thrombosis (central or branch). Antithrombin III, coagulant protein C, functional protein S, resistance to activated C protein, homocysteine, prothrombin G20210A gene, lupus anticoagulant and anticardiolipin antibodies were measured in all. Results: Seventeen patients had thrombophilic markers (antiphospholipid syndrome in seven, hyperhomocysteinemia in six and resistance to protein C in three). Of these 17 patients, 53% had high blood pressure, 35% an abnormal serum lipid profile and 23% a personal history of thrombosis. The thrombosis was central in 12 (ischemic in four) and of a branch in five (ischemic in two). Conclusions: Thrombophilic markers must be assessed in patients with retinal vein thrombosis (Rev Méd Chile 2005; 133: 167-74)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.2 20052005-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200003es10.4067/S0034-98872005000200003 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Activated protein C resistance Antiphospholipid syndrome Retinal vein occlusion Thrombophilia |
spellingShingle |
Activated protein C resistance Antiphospholipid syndrome Retinal vein occlusion Thrombophilia Traipe C,Leonidas Conte L,Guillermo Conte S,Francisco J Ibáñez L,Santiago Meza R,Patricio Rojas U,Basilio Cuneo V,Marianela Verdaguer T,Juan Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas |
description |
Background: Thrombophilia is an alteration of hemostasis that increases the risk to venous or arterial thrombosis. This condition may be the underlying cause of retinal vein thrombosis. Aim: To study the presence of thrombophilia in patients with retinal vein thrombosis. Patients and methods: Prospective study of 55 patients aged 22 to 86 years, with retinal vein thrombosis (central or branch). Antithrombin III, coagulant protein C, functional protein S, resistance to activated C protein, homocysteine, prothrombin G20210A gene, lupus anticoagulant and anticardiolipin antibodies were measured in all. Results: Seventeen patients had thrombophilic markers (antiphospholipid syndrome in seven, hyperhomocysteinemia in six and resistance to protein C in three). Of these 17 patients, 53% had high blood pressure, 35% an abnormal serum lipid profile and 23% a personal history of thrombosis. The thrombosis was central in 12 (ischemic in four) and of a branch in five (ischemic in two). Conclusions: Thrombophilic markers must be assessed in patients with retinal vein thrombosis (Rev Méd Chile 2005; 133: 167-74) |
author |
Traipe C,Leonidas Conte L,Guillermo Conte S,Francisco J Ibáñez L,Santiago Meza R,Patricio Rojas U,Basilio Cuneo V,Marianela Verdaguer T,Juan |
author_facet |
Traipe C,Leonidas Conte L,Guillermo Conte S,Francisco J Ibáñez L,Santiago Meza R,Patricio Rojas U,Basilio Cuneo V,Marianela Verdaguer T,Juan |
author_sort |
Traipe C,Leonidas |
title |
Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas |
title_short |
Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas |
title_full |
Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas |
title_fullStr |
Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas |
title_full_unstemmed |
Determinación de factores trombofílicos en pacientes con trombosis venosas retinianas |
title_sort |
determinación de factores trombofílicos en pacientes con trombosis venosas retinianas |
publisher |
Sociedad Médica de Santiago |
publishDate |
2005 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200003 |
work_keys_str_mv |
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