Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis

Objective: To compare the safety and clinical outcomes of enteral and parenteral nutrition in patients with acute pancreatitis. Data sources: Medline, Embase, Cochrane controlled trials register, and citation review of relevant primary and review articles. Study selection: Randomized controlled stud...

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Autores principales:	Manríquez M,Juan Jorge, Letelier S,Luz María
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2005
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200016
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spelling	oai:scielo:S0034-988720050002000162005-04-12Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitisManríquez M,Juan JorgeLetelier S,Luz MaríaObjective: To compare the safety and clinical outcomes of enteral and parenteral nutrition in patients with acute pancreatitis. Data sources: Medline, Embase, Cochrane controlled trials register, and citation review of relevant primary and review articles. Study selection: Randomized controlled studies that compared enteral nutrition with parenteral nutrition in patients with acute pancreatitis. From 117 articles screened, six were identified as randomized controlled trials and were included for data extraction. Data extraction: Six studies with 263 participants were analyzed. Descriptive and outcome data were extracted. Main outcome measures were infections, complications other than infections, operative interventions, length of hospital stay, and mortality. The metaanalysis was performed with the random effects model. Data synthesis: Enteral nutrition was associated with a significantly lower incidence of infections (relative risk 0.45; 95% confidence interval 0.26 to 0.78, P= 0.004), reduced surgical interventions to control pancreatitis (0.48, 0.22 to 1.0, P= 0.05), and a reduced length of hospital stay (mean reduction 2.9 days, 1.6 days to 4.3 days, P <0.001). There were no significant differences in mortality (relative risk 0.66, 0.32 to 1.37, P = 0.3) or non-infectious complications (0.61, 0.31 to 1.22, P= 0.16) between the two groups of patients. Conclusions: Enteral nutrition should be the preferred route of nutritional support in patients with acute pancreatitisinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.2 20052005-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200016es10.4067/S0034-98872005000200016
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
description	Objective: To compare the safety and clinical outcomes of enteral and parenteral nutrition in patients with acute pancreatitis. Data sources: Medline, Embase, Cochrane controlled trials register, and citation review of relevant primary and review articles. Study selection: Randomized controlled studies that compared enteral nutrition with parenteral nutrition in patients with acute pancreatitis. From 117 articles screened, six were identified as randomized controlled trials and were included for data extraction. Data extraction: Six studies with 263 participants were analyzed. Descriptive and outcome data were extracted. Main outcome measures were infections, complications other than infections, operative interventions, length of hospital stay, and mortality. The metaanalysis was performed with the random effects model. Data synthesis: Enteral nutrition was associated with a significantly lower incidence of infections (relative risk 0.45; 95% confidence interval 0.26 to 0.78, P= 0.004), reduced surgical interventions to control pancreatitis (0.48, 0.22 to 1.0, P= 0.05), and a reduced length of hospital stay (mean reduction 2.9 days, 1.6 days to 4.3 days, P <0.001). There were no significant differences in mortality (relative risk 0.66, 0.32 to 1.37, P = 0.3) or non-infectious complications (0.61, 0.31 to 1.22, P= 0.16) between the two groups of patients. Conclusions: Enteral nutrition should be the preferred route of nutritional support in patients with acute pancreatitis
author	Manríquez M,Juan Jorge Letelier S,Luz María
spellingShingle	Manríquez M,Juan Jorge Letelier S,Luz María Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis
author_facet	Manríquez M,Juan Jorge Letelier S,Luz María
author_sort	Manríquez M,Juan Jorge
title	Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis
title_short	Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis
title_full	Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis
title_fullStr	Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis
title_full_unstemmed	Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis
title_sort	análisis crítico de un artículo: critical appraisal: enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis
publisher	Sociedad Médica de Santiago
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000200016
work_keys_str_mv	AT manriquezmjuanjorge analisiscriticodeunarticulocriticalappraisalenteralnutritionisbetterthanparenteralnutritionforpatientswithacutepancreatitis AT leteliersluzmaria analisiscriticodeunarticulocriticalappraisalenteralnutritionisbetterthanparenteralnutritionforpatientswithacutepancreatitis
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Análisis crítico de un artículo: Critical Appraisal: Enteral nutrition is better than parenteral nutrition for patients with acute pancreatitis

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