Malformaciones congénitas en hijos de madres con diabetes gestacional

Background: The risk of congenital malformations is two to three times higher among women with diabetes mellitus before pregnancy. Gestacional diabetes is emerging as a risk factor for malformations. Aim: To study the rate and type of congenital malformations among offspring of women with pre-gestat...

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Autores principales:	Nazer Herrera,Julio, García Huidobro,Moira, Cifuentes Ovalle,Lucía
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2005
Materias:	Abnormalities Congenital, hereditary, and neonatal diseases and abnormalities Diabetes, gestational
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000500006
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spelling	oai:scielo:S0034-988720050005000062005-06-17Malformaciones congénitas en hijos de madres con diabetes gestacionalNazer Herrera,JulioGarcía Huidobro,MoiraCifuentes Ovalle,Lucía Abnormalities Congenital, hereditary, and neonatal diseases and abnormalities Diabetes, gestational Background: The risk of congenital malformations is two to three times higher among women with diabetes mellitus before pregnancy. Gestacional diabetes is emerging as a risk factor for malformations. Aim: To study the rate and type of congenital malformations among offspring of women with pre-gestational or gestational diabetes. Material and methods: A search in the databases of the Collaborative Latin American Study for Congenital Malformations and of the Neonatology Unity of The University of Chile Clinical Hospital. All births from January 1998 through June 2004 were investigated. Results: In the study period, 13,965 births occurred, of which 0.7% were stillbirths and 8.1% had malformations. A total of 295 women (2.1%) had diabetes (gestational diabetes in 1.8% and pre gestational diabetes in 0.3%). The prevalence of congenital malformations was 14% and 18.3% among offspring of mothers with pre-gestational and gestational diabetes, respectively (p=NS). The prevalence of congenital malformations among offspring of non diabetic women was 7.9% (p <0.001 with respect to diabetic women). Major malformations were found in 83% and 70% of malformed offspring of women with pre-gestational and gestational diabetes, respectively. Conclusions: Pregnant women with pre-existing or gestational diabetes have a higher risk of giving birth a child with malformationsinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.5 20052005-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000500006es10.4067/S0034-98872005000500006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Abnormalities Congenital, hereditary, and neonatal diseases and abnormalities Diabetes, gestational
spellingShingle	Abnormalities Congenital, hereditary, and neonatal diseases and abnormalities Diabetes, gestational Nazer Herrera,Julio García Huidobro,Moira Cifuentes Ovalle,Lucía Malformaciones congénitas en hijos de madres con diabetes gestacional
description	Background: The risk of congenital malformations is two to three times higher among women with diabetes mellitus before pregnancy. Gestacional diabetes is emerging as a risk factor for malformations. Aim: To study the rate and type of congenital malformations among offspring of women with pre-gestational or gestational diabetes. Material and methods: A search in the databases of the Collaborative Latin American Study for Congenital Malformations and of the Neonatology Unity of The University of Chile Clinical Hospital. All births from January 1998 through June 2004 were investigated. Results: In the study period, 13,965 births occurred, of which 0.7% were stillbirths and 8.1% had malformations. A total of 295 women (2.1%) had diabetes (gestational diabetes in 1.8% and pre gestational diabetes in 0.3%). The prevalence of congenital malformations was 14% and 18.3% among offspring of mothers with pre-gestational and gestational diabetes, respectively (p=NS). The prevalence of congenital malformations among offspring of non diabetic women was 7.9% (p <0.001 with respect to diabetic women). Major malformations were found in 83% and 70% of malformed offspring of women with pre-gestational and gestational diabetes, respectively. Conclusions: Pregnant women with pre-existing or gestational diabetes have a higher risk of giving birth a child with malformations
author	Nazer Herrera,Julio García Huidobro,Moira Cifuentes Ovalle,Lucía
author_facet	Nazer Herrera,Julio García Huidobro,Moira Cifuentes Ovalle,Lucía
author_sort	Nazer Herrera,Julio
title	Malformaciones congénitas en hijos de madres con diabetes gestacional
title_short	Malformaciones congénitas en hijos de madres con diabetes gestacional
title_full	Malformaciones congénitas en hijos de madres con diabetes gestacional
title_fullStr	Malformaciones congénitas en hijos de madres con diabetes gestacional
title_full_unstemmed	Malformaciones congénitas en hijos de madres con diabetes gestacional
title_sort	malformaciones congénitas en hijos de madres con diabetes gestacional
publisher	Sociedad Médica de Santiago
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000500006
work_keys_str_mv	AT nazerherrerajulio malformacionescongenitasenhijosdemadrescondiabetesgestacional AT garciahuidobromoira malformacionescongenitasenhijosdemadrescondiabetesgestacional AT cifuentesovallelucia malformacionescongenitasenhijosdemadrescondiabetesgestacional
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Malformaciones congénitas en hijos de madres con diabetes gestacional

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