Anti-VHE IgM en casos de infección por el virus hepatitis E

Background: Hepatitis E virus is the main enterically transmitted non A non B hepatitis agent. The host IgM response in the acute infection phase is short lived. Therefore, only IgG antibodies against E virus are usually investigated. Aim: To measure IgM antibodies against virus E in serum samples....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hurtado H,Carmen, Muñoz G,Gabriela, Brahm B,Javier
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2005
Materias:	Antibodies, viral Hepatitis E virus Immunologic factors
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000600004
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872005000600004
record_format	dspace
spelling	oai:scielo:S0034-988720050006000042005-08-26Anti-VHE IgM en casos de infección por el virus hepatitis EHurtado H,CarmenMuñoz G,GabrielaBrahm B,Javier Antibodies, viral Hepatitis E virus Immunologic factors Background: Hepatitis E virus is the main enterically transmitted non A non B hepatitis agent. The host IgM response in the acute infection phase is short lived. Therefore, only IgG antibodies against E virus are usually investigated. Aim: To measure IgM antibodies against virus E in serum samples. Material and Methods: IgM antibodies against virus E were measured by ELISA in 35 positive and 18 negative serum samples for IgG antibodies against hepatitis virus E, without evidence of infection with hepatitis A, B or C virus. Measurement of the same antibodies in 25 additional samples positive for IgM antibodies against hepatitis A virus but without study for hepatitis virus B or C. Results: IgM antibodies against virus E were detected in 12 of the 35 samples positive for IgG antibodies (34%) and in five of the 25 samples positive for antibodies against virus A (20%). Conclusions: An acute hepatitis E virus infection was detected in 34% of samples positive for IgG antibodies against this virus. The absence of IgM antibodies in the rest of the IgG positive samples could be due to an old or a recent virus E infection in the stage of antibody titer reduction. The detection of IgM antibodies against virus E in samples positive for virus A antibodies, could be due to co infection by virus A and E or a cross reaction of assaysinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.6 20052005-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000600004es10.4067/S0034-98872005000600004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Antibodies, viral Hepatitis E virus Immunologic factors
spellingShingle	Antibodies, viral Hepatitis E virus Immunologic factors Hurtado H,Carmen Muñoz G,Gabriela Brahm B,Javier Anti-VHE IgM en casos de infección por el virus hepatitis E
description	Background: Hepatitis E virus is the main enterically transmitted non A non B hepatitis agent. The host IgM response in the acute infection phase is short lived. Therefore, only IgG antibodies against E virus are usually investigated. Aim: To measure IgM antibodies against virus E in serum samples. Material and Methods: IgM antibodies against virus E were measured by ELISA in 35 positive and 18 negative serum samples for IgG antibodies against hepatitis virus E, without evidence of infection with hepatitis A, B or C virus. Measurement of the same antibodies in 25 additional samples positive for IgM antibodies against hepatitis A virus but without study for hepatitis virus B or C. Results: IgM antibodies against virus E were detected in 12 of the 35 samples positive for IgG antibodies (34%) and in five of the 25 samples positive for antibodies against virus A (20%). Conclusions: An acute hepatitis E virus infection was detected in 34% of samples positive for IgG antibodies against this virus. The absence of IgM antibodies in the rest of the IgG positive samples could be due to an old or a recent virus E infection in the stage of antibody titer reduction. The detection of IgM antibodies against virus E in samples positive for virus A antibodies, could be due to co infection by virus A and E or a cross reaction of assays
author	Hurtado H,Carmen Muñoz G,Gabriela Brahm B,Javier
author_facet	Hurtado H,Carmen Muñoz G,Gabriela Brahm B,Javier
author_sort	Hurtado H,Carmen
title	Anti-VHE IgM en casos de infección por el virus hepatitis E
title_short	Anti-VHE IgM en casos de infección por el virus hepatitis E
title_full	Anti-VHE IgM en casos de infección por el virus hepatitis E
title_fullStr	Anti-VHE IgM en casos de infección por el virus hepatitis E
title_full_unstemmed	Anti-VHE IgM en casos de infección por el virus hepatitis E
title_sort	anti-vhe igm en casos de infección por el virus hepatitis e
publisher	Sociedad Médica de Santiago
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000600004
work_keys_str_mv	AT hurtadohcarmen antivheigmencasosdeinfeccionporelvirushepatitise AT munozggabriela antivheigmencasosdeinfeccionporelvirushepatitise AT brahmbjavier antivheigmencasosdeinfeccionporelvirushepatitise
_version_	1718436208614309888

Anti-VHE IgM en casos de infección por el virus hepatitis E

Ejemplares similares