Amiloidosis, Comunicación de 11 casos y revisión de la literatura

Background: Amyloidosis is characterized by the extracellular deposit of an insoluble fibrillar protein that leads to tissue atrophy and necrosis. Aim: To report the clinical features of cases of amyloidosis diagnosed in a public hospital in Santiago, Chile, from 2000 to 2004. Material and methods:...

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Autores principales:	Palma R,Carmen Luz, Grünholz G,Daniela, Osorio S,Guido
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2005
Materias:	Amyloidosis Kidney failure chronic Tuberculosis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000600006
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spelling	oai:scielo:S0034-988720050006000062005-08-26Amiloidosis, Comunicación de 11 casos y revisión de la literaturaPalma R,Carmen LuzGrünholz G,DanielaOsorio S,Guido Amyloidosis Kidney failure chronic Tuberculosis Background: Amyloidosis is characterized by the extracellular deposit of an insoluble fibrillar protein that leads to tissue atrophy and necrosis. Aim: To report the clinical features of cases of amyloidosis diagnosed in a public hospital in Santiago, Chile, from 2000 to 2004. Material and methods: Retrospective review of all pathology reports of biopsies obtained from 2000 to 2004. In all cases reported as "amyloidosis", the clinical features of such patients were obtained from their medical records. Results: The medical records of 11 patients with amyloidosis were obtained (aged 35 to 71 year old, seven females). Seven had a systemic and four a localized disease. Six patients had primary amyloidosis and in one, it was secondary to a disseminated tuberculosis. Five patients with the generalized disease consulted for anarsarca, three for weight loss and 2 for chronic diarrhea. Patients with localized disease consulted for tonsil enlargement, dysphonia and skin lesions. Five patients with generalized disease had renal involvement and five had cardiac involvement. Three patients had malabsorption. Conclusions: The most common presentation of systemic amyloidosis is anasarca and renal involvement is commoninfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.6 20052005-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000600006es10.4067/S0034-98872005000600006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Amyloidosis Kidney failure chronic Tuberculosis
spellingShingle	Amyloidosis Kidney failure chronic Tuberculosis Palma R,Carmen Luz Grünholz G,Daniela Osorio S,Guido Amiloidosis, Comunicación de 11 casos y revisión de la literatura
description	Background: Amyloidosis is characterized by the extracellular deposit of an insoluble fibrillar protein that leads to tissue atrophy and necrosis. Aim: To report the clinical features of cases of amyloidosis diagnosed in a public hospital in Santiago, Chile, from 2000 to 2004. Material and methods: Retrospective review of all pathology reports of biopsies obtained from 2000 to 2004. In all cases reported as "amyloidosis", the clinical features of such patients were obtained from their medical records. Results: The medical records of 11 patients with amyloidosis were obtained (aged 35 to 71 year old, seven females). Seven had a systemic and four a localized disease. Six patients had primary amyloidosis and in one, it was secondary to a disseminated tuberculosis. Five patients with the generalized disease consulted for anarsarca, three for weight loss and 2 for chronic diarrhea. Patients with localized disease consulted for tonsil enlargement, dysphonia and skin lesions. Five patients with generalized disease had renal involvement and five had cardiac involvement. Three patients had malabsorption. Conclusions: The most common presentation of systemic amyloidosis is anasarca and renal involvement is common
author	Palma R,Carmen Luz Grünholz G,Daniela Osorio S,Guido
author_facet	Palma R,Carmen Luz Grünholz G,Daniela Osorio S,Guido
author_sort	Palma R,Carmen Luz
title	Amiloidosis, Comunicación de 11 casos y revisión de la literatura
title_short	Amiloidosis, Comunicación de 11 casos y revisión de la literatura
title_full	Amiloidosis, Comunicación de 11 casos y revisión de la literatura
title_fullStr	Amiloidosis, Comunicación de 11 casos y revisión de la literatura
title_full_unstemmed	Amiloidosis, Comunicación de 11 casos y revisión de la literatura
title_sort	amiloidosis, comunicación de 11 casos y revisión de la literatura
publisher	Sociedad Médica de Santiago
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000600006
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Amiloidosis, Comunicación de 11 casos y revisión de la literatura

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