Síndrome hemolítico urémico: Experiencia de un centro pediátrico

Background:Hemolytic uremic syndrome (HUS) is one of the main causes of acute renal failure in the Chilean pediatric population. Aim: To report the features of patients with HUS, admitted to the pediatric ward of a clinical hospital. Material and methods: Retrospective review of medical records of p...

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Autores principales:	Cavagnaro SM,Felipe, Gana A,Juan Cristóbal, Lagomarsino F,Edda, Vogel S,Andrea, Gederlini G,Alejandra
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2005
Materias:	Hemolytic-uremic syndrome Kidney failure peritoneal dialysis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000700005
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spelling	oai:scielo:S0034-988720050007000052014-08-12Síndrome hemolítico urémico: Experiencia de un centro pediátricoCavagnaro SM,FelipeGana A,Juan CristóbalLagomarsino F,EddaVogel S,AndreaGederlini G,Alejandra Hemolytic-uremic syndrome Kidney failure peritoneal dialysis Background:Hemolytic uremic syndrome (HUS) is one of the main causes of acute renal failure in the Chilean pediatric population. Aim: To report the features of patients with HUS, admitted to the pediatric ward of a clinical hospital. Material and methods: Retrospective review of medical records of patients admitted with the diagnosis of HUS between 1995 and 2002. Results: During the period, 58 patients were admitted with the diagnosis of HUS but only 43 (age range 1 month to 6 years, 22 females) had complete medical records for review. Ninety five percent presented with prodromic diarrhea, mainly dysenteric. Antibiotics were administered to 70%, in the previous days. Acute renal replacement, mainly peritoneal dialysis, was required in 40%. The clinical signs and laboratory parameters that correlated better with the indication for dialysis were anuria, hypertension, initial and permanently high serum creatinine and blood urea nitrogen. Four patients with blood urea nitrogen over 100 mg/dl but without anuria or hyperkalemia, were treated conservatively, and experienced an uneventful course (permissive azotemia). Hospital stay was almost 3 times greater in dialyzed than in non dialyzed children. No deaths related to HUS were reported in the study period. In an average follow up of 54 months, 11.6% of the patients developed chronic renal failure of diverse magnitude. Conclusions: Despite the fact that our study group behaved clinically similar to published HUS patients in other series, no mortality was observed in a retrospective analysis of patients with this diseaseinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.7 20052005-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000700005es10.4067/S0034-98872005000700005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hemolytic-uremic syndrome Kidney failure peritoneal dialysis
spellingShingle	Hemolytic-uremic syndrome Kidney failure peritoneal dialysis Cavagnaro SM,Felipe Gana A,Juan Cristóbal Lagomarsino F,Edda Vogel S,Andrea Gederlini G,Alejandra Síndrome hemolítico urémico: Experiencia de un centro pediátrico
description	Background:Hemolytic uremic syndrome (HUS) is one of the main causes of acute renal failure in the Chilean pediatric population. Aim: To report the features of patients with HUS, admitted to the pediatric ward of a clinical hospital. Material and methods: Retrospective review of medical records of patients admitted with the diagnosis of HUS between 1995 and 2002. Results: During the period, 58 patients were admitted with the diagnosis of HUS but only 43 (age range 1 month to 6 years, 22 females) had complete medical records for review. Ninety five percent presented with prodromic diarrhea, mainly dysenteric. Antibiotics were administered to 70%, in the previous days. Acute renal replacement, mainly peritoneal dialysis, was required in 40%. The clinical signs and laboratory parameters that correlated better with the indication for dialysis were anuria, hypertension, initial and permanently high serum creatinine and blood urea nitrogen. Four patients with blood urea nitrogen over 100 mg/dl but without anuria or hyperkalemia, were treated conservatively, and experienced an uneventful course (permissive azotemia). Hospital stay was almost 3 times greater in dialyzed than in non dialyzed children. No deaths related to HUS were reported in the study period. In an average follow up of 54 months, 11.6% of the patients developed chronic renal failure of diverse magnitude. Conclusions: Despite the fact that our study group behaved clinically similar to published HUS patients in other series, no mortality was observed in a retrospective analysis of patients with this disease
author	Cavagnaro SM,Felipe Gana A,Juan Cristóbal Lagomarsino F,Edda Vogel S,Andrea Gederlini G,Alejandra
author_facet	Cavagnaro SM,Felipe Gana A,Juan Cristóbal Lagomarsino F,Edda Vogel S,Andrea Gederlini G,Alejandra
author_sort	Cavagnaro SM,Felipe
title	Síndrome hemolítico urémico: Experiencia de un centro pediátrico
title_short	Síndrome hemolítico urémico: Experiencia de un centro pediátrico
title_full	Síndrome hemolítico urémico: Experiencia de un centro pediátrico
title_fullStr	Síndrome hemolítico urémico: Experiencia de un centro pediátrico
title_full_unstemmed	Síndrome hemolítico urémico: Experiencia de un centro pediátrico
title_sort	síndrome hemolítico urémico: experiencia de un centro pediátrico
publisher	Sociedad Médica de Santiago
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000700005
work_keys_str_mv	AT cavagnarosmfelipe sindromehemoliticouremicoexperienciadeuncentropediatrico AT ganaajuancristobal sindromehemoliticouremicoexperienciadeuncentropediatrico AT lagomarsinofedda sindromehemoliticouremicoexperienciadeuncentropediatrico AT vogelsandrea sindromehemoliticouremicoexperienciadeuncentropediatrico AT gederlinigalejandra sindromehemoliticouremicoexperienciadeuncentropediatrico
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Síndrome hemolítico urémico: Experiencia de un centro pediátrico

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