Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas

Background: Cefpodoxime is a new antimicrobial in the Chilean market, recommended for treatment of respiratory and urinary tract infections. Aim: To study the susceptibility of common pathogens isolated from Chilean patients to cefpodoxime and other antimicrobials. Material and methods: The in vitro...

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Autores principales:	Silva O,Francisco, Durán T,Claudia, Ulloa F,María Teresa, Prado J,Valeria
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2005
Materias:	Cefpodoxime Cephalosporins Drug resistance, bacterial Respiratory tract infections Urinary tract infections
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000800006
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spelling	oai:scielo:S0034-988720050008000062014-08-12Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandasSilva O,FranciscoDurán T,ClaudiaUlloa F,María TeresaPrado J,Valeria Cefpodoxime Cephalosporins Drug resistance, bacterial Respiratory tract infections Urinary tract infections Background: Cefpodoxime is a new antimicrobial in the Chilean market, recommended for treatment of respiratory and urinary tract infections. Aim: To study the susceptibility of common pathogens isolated from Chilean patients to cefpodoxime and other antimicrobials. Material and methods: The in vitro activity of cefpodoxime, expressed as Minimal Inhibitory Concentration, was studied in 331 S pneumoniae, H influenzae, M catarrhalis, E coli, S aureus and S pyogenes strains, isolated between 2000 and 2004 from respiratory, urinary and soft tissue infections, respectively. Results: Eleven percent of S pneumoniae isolates were resistant to penicillin, 11% were resistant to cefuroxime and 10% to cefpodoxime. All H influenzae isolates were susceptible to cefpodoxime. No H influenzae isolates were resistant to second or third generation cephalosporines. Four percent of H influenzae isolates were resistant to ampicillin by ß-lactamase production. In contrast 81% of M catarrhalis strains were resistant to ampicillin. Six percent of E coli isolates were resistant to cefpodoxime, 9% to cefuroxime, 11% to cefadroxile and 50% to ampicillin or trimethoprim/sulphamethoxazole. Cefpodoxime was the most active antimicrobial against S pyogenes. Conclusions: Cefpodoxime, recently introduced in Chile, is a good alternative for the treatment of common respiratory and urinary tract infectionsinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.8 20052005-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000800006es10.4067/S0034-98872005000800006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cefpodoxime Cephalosporins Drug resistance, bacterial Respiratory tract infections Urinary tract infections
spellingShingle	Cefpodoxime Cephalosporins Drug resistance, bacterial Respiratory tract infections Urinary tract infections Silva O,Francisco Durán T,Claudia Ulloa F,María Teresa Prado J,Valeria Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas
description	Background: Cefpodoxime is a new antimicrobial in the Chilean market, recommended for treatment of respiratory and urinary tract infections. Aim: To study the susceptibility of common pathogens isolated from Chilean patients to cefpodoxime and other antimicrobials. Material and methods: The in vitro activity of cefpodoxime, expressed as Minimal Inhibitory Concentration, was studied in 331 S pneumoniae, H influenzae, M catarrhalis, E coli, S aureus and S pyogenes strains, isolated between 2000 and 2004 from respiratory, urinary and soft tissue infections, respectively. Results: Eleven percent of S pneumoniae isolates were resistant to penicillin, 11% were resistant to cefuroxime and 10% to cefpodoxime. All H influenzae isolates were susceptible to cefpodoxime. No H influenzae isolates were resistant to second or third generation cephalosporines. Four percent of H influenzae isolates were resistant to ampicillin by ß-lactamase production. In contrast 81% of M catarrhalis strains were resistant to ampicillin. Six percent of E coli isolates were resistant to cefpodoxime, 9% to cefuroxime, 11% to cefadroxile and 50% to ampicillin or trimethoprim/sulphamethoxazole. Cefpodoxime was the most active antimicrobial against S pyogenes. Conclusions: Cefpodoxime, recently introduced in Chile, is a good alternative for the treatment of common respiratory and urinary tract infections
author	Silva O,Francisco Durán T,Claudia Ulloa F,María Teresa Prado J,Valeria
author_facet	Silva O,Francisco Durán T,Claudia Ulloa F,María Teresa Prado J,Valeria
author_sort	Silva O,Francisco
title	Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas
title_short	Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas
title_full	Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas
title_fullStr	Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas
title_full_unstemmed	Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas
title_sort	actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas
publisher	Sociedad Médica de Santiago
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000800006
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Actividad comparativa in vitro de cefpodoxima en relación a otros antibióticos de uso frecuente, frente a patógenos respiratorios, urinarios y de infecciones de partes blandas

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