Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003

Background: The Latin American Collaborative Study for Congenital Malformations (ECLAMC) has detected a higher incidence of Down syndrome in a zone of central Chile than in the rest of the country. Aim: To analyze the incidence rates of Down syndrome between 1997 and 2003 at the Regional Hospital of...

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Autores principales:	Ojeda B,María Elena, Moreno S,Rodrigo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2005
Materias:	Down syndrome Epidemiology Genetics, medical
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000800010
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spelling	oai:scielo:S0034-988720050008000102014-08-12Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003Ojeda B,María ElenaMoreno S,Rodrigo Down syndrome Epidemiology Genetics, medical Background: The Latin American Collaborative Study for Congenital Malformations (ECLAMC) has detected a higher incidence of Down syndrome in a zone of central Chile than in the rest of the country. Aim: To analyze the incidence rates of Down syndrome between 1997 and 2003 at the Regional Hospital of Rancagua, located 90 km south of Santiago, Chile. Material and methods: The information obtained by ECLAMC was used. This program, using a case control methodology, registers all newborns with congenital malformations and assigns, as a control, the next normal newborn of the same sex. Results: During the study period, 106 newborns with Down syndrome were registered, with a mean rate of 29.61 per 10,000 live births, twice higher than expected. The rate variations along the years of study suggest a cyclic change, with a hemicycle of six years. Conclusions: In this hospital, mothers under 35 years of age, have twice the risk of having a child with Down syndrome, than in the rest of the countryinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.8 20052005-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000800010es10.4067/S0034-98872005000800010
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Down syndrome Epidemiology Genetics, medical
spellingShingle	Down syndrome Epidemiology Genetics, medical Ojeda B,María Elena Moreno S,Rodrigo Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003
description	Background: The Latin American Collaborative Study for Congenital Malformations (ECLAMC) has detected a higher incidence of Down syndrome in a zone of central Chile than in the rest of the country. Aim: To analyze the incidence rates of Down syndrome between 1997 and 2003 at the Regional Hospital of Rancagua, located 90 km south of Santiago, Chile. Material and methods: The information obtained by ECLAMC was used. This program, using a case control methodology, registers all newborns with congenital malformations and assigns, as a control, the next normal newborn of the same sex. Results: During the study period, 106 newborns with Down syndrome were registered, with a mean rate of 29.61 per 10,000 live births, twice higher than expected. The rate variations along the years of study suggest a cyclic change, with a hemicycle of six years. Conclusions: In this hospital, mothers under 35 years of age, have twice the risk of having a child with Down syndrome, than in the rest of the country
author	Ojeda B,María Elena Moreno S,Rodrigo
author_facet	Ojeda B,María Elena Moreno S,Rodrigo
author_sort	Ojeda B,María Elena
title	Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003
title_short	Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003
title_full	Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003
title_fullStr	Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003
title_full_unstemmed	Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003
title_sort	alta prevalencia de síndrome de down en el hospital regional rancagua, chile: período 1997-2003
publisher	Sociedad Médica de Santiago
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005000800010
work_keys_str_mv	AT ojedabmariaelena altaprevalenciadesindromededownenelhospitalregionalrancaguachileperiodo19972003 AT morenosrodrigo altaprevalenciadesindromededownenelhospitalregionalrancaguachileperiodo19972003
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Alta prevalencia de síndrome de Down en el Hospital Regional Rancagua, Chile: Período 1997-2003

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