La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruzi

At the present time the assessment of results of treatment of Chagas disease is mainly parasitological. Anti Trypanosoma cruzi IgGs remain positive practically lifelong and electrocardiographic tracings are not usually used as criteria of improvement. Aim: To determine, in a long term follow up, if...

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Autores principales:	Zulantay A,Inés, Arribada C,Arturo, Honores P,Patricia, Sánchez P,Gittith, Solari I,Aldo, Ortiz Z,Sylvia, Osuna C,Antonio, Rodríguez T,Jorge, Werner Apt,B
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2005
Materias:	Chagas cardiomyopathy Chagas disease Electro cardiography
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005001000004
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spelling	oai:scielo:S0034-988720050010000042005-12-05La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruziZulantay A,InésArribada C,ArturoHonores P,PatriciaSánchez P,GittithSolari I,AldoOrtiz Z,SylviaOsuna C,AntonioRodríguez T,JorgeWerner Apt,B Chagas cardiomyopathy Chagas disease Electro cardiography At the present time the assessment of results of treatment of Chagas disease is mainly parasitological. Anti Trypanosoma cruzi IgGs remain positive practically lifelong and electrocardiographic tracings are not usually used as criteria of improvement. Aim: To determine, in a long term follow up, if electrocardiographic evolution is associated with the persistence of the parasite in treated patients with chronic Chagas disease. Material and methods: Thirty patients with chronic Chagas disease that participated in a randomized trial of treatment with itraconazole or allopurinol, were studied. Seven years after treatment, patients were classified in group I if they had a positive xenodiagnosis test, polymerase chain reaction and hybridization in blood or in group II if they had negative tests. A 12 lead electrocardiogram (EKG) was performed each year to all patients. Results: Seventeen patients were classified in group I and 13 in group II. At baseline 10 patients in group I and 8 in group II had a normal EKG. Six years after treatment 13 patients in group I and 10 in group II had a normal tracing. Of those with a normal tracing at baseline, only one patient in each group presented alterations after six years. A regression of abnormal tracings was observed in four and three patients of groups I and II respectively. Conclusions: There is no association between the persistence of the parasite in treated patients with Chagas disease and the evolution of electrocardiographic tracings (Rev Méd Chile 2005; 133: 1153-60)info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.133 n.10 20052005-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005001000004es10.4067/S0034-98872005001000004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Chagas cardiomyopathy Chagas disease Electro cardiography
spellingShingle	Chagas cardiomyopathy Chagas disease Electro cardiography Zulantay A,Inés Arribada C,Arturo Honores P,Patricia Sánchez P,Gittith Solari I,Aldo Ortiz Z,Sylvia Osuna C,Antonio Rodríguez T,Jorge Werner Apt,B La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruzi
description	At the present time the assessment of results of treatment of Chagas disease is mainly parasitological. Anti Trypanosoma cruzi IgGs remain positive practically lifelong and electrocardiographic tracings are not usually used as criteria of improvement. Aim: To determine, in a long term follow up, if electrocardiographic evolution is associated with the persistence of the parasite in treated patients with chronic Chagas disease. Material and methods: Thirty patients with chronic Chagas disease that participated in a randomized trial of treatment with itraconazole or allopurinol, were studied. Seven years after treatment, patients were classified in group I if they had a positive xenodiagnosis test, polymerase chain reaction and hybridization in blood or in group II if they had negative tests. A 12 lead electrocardiogram (EKG) was performed each year to all patients. Results: Seventeen patients were classified in group I and 13 in group II. At baseline 10 patients in group I and 8 in group II had a normal EKG. Six years after treatment 13 patients in group I and 10 in group II had a normal tracing. Of those with a normal tracing at baseline, only one patient in each group presented alterations after six years. A regression of abnormal tracings was observed in four and three patients of groups I and II respectively. Conclusions: There is no association between the persistence of the parasite in treated patients with Chagas disease and the evolution of electrocardiographic tracings (Rev Méd Chile 2005; 133: 1153-60)
author	Zulantay A,Inés Arribada C,Arturo Honores P,Patricia Sánchez P,Gittith Solari I,Aldo Ortiz Z,Sylvia Osuna C,Antonio Rodríguez T,Jorge Werner Apt,B
author_facet	Zulantay A,Inés Arribada C,Arturo Honores P,Patricia Sánchez P,Gittith Solari I,Aldo Ortiz Z,Sylvia Osuna C,Antonio Rodríguez T,Jorge Werner Apt,B
author_sort	Zulantay A,Inés
title	La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruzi
title_short	La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruzi
title_full	La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruzi
title_fullStr	La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruzi
title_full_unstemmed	La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruzi
title_sort	la mejoría electrocardiográfica con el tratamiento de la enfermedad de chagas crónica, es independiente de la persistencia de trypanosoma cruzi
publisher	Sociedad Médica de Santiago
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872005001000004
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La mejoría electrocardiográfica con el tratamiento de la enfermedad de Chagas crónica, es independiente de la persistencia de Trypanosoma cruzi

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