Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos

Background: The use of inhaled steroids is common in the treatment of bronchial asthma in children. Aim: To assess adrenocortical function in children with severe asthma receiving inhaled budesonide for six or more months. Material and methods: Children with severe asthma that required 800 µg/day or...

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Autores principales:	Milinarsky T,Aída, Fischer G,Sylvia, Giadrosich R,Vinka, Lezana S,Viviana, Torres C,María Teresa
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2006
Materias:	Adrenal cortex function tests Asthma Budesonide Hydrocortisone
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000100008
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spelling	oai:scielo:S0034-988720060001000082006-03-08Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severosMilinarsky T,AídaFischer G,SylviaGiadrosich R,VinkaLezana S,VivianaTorres C,María Teresa Adrenal cortex function tests Asthma Budesonide Hydrocortisone Background: The use of inhaled steroids is common in the treatment of bronchial asthma in children. Aim: To assess adrenocortical function in children with severe asthma receiving inhaled budesonide for six or more months. Material and methods: Children with severe asthma that required 800 µg/day or more of inhaled budesonide and that did not required systemic steroids for more than six days in the last four months to control their disease, were studied. Serum cortisol was measured one hour after administration of 0.25 mg of ACTH (Cosyntropin®) intravenously. The test was considered normal if post stimulation serum cortisol was over 18 µg/ml. Results: Twenty children (aged 5 to 14 years, 15 males), were studied. The stimulation test was normal in 17 children. Conclusions: Alterations in adrenal function are present in a small proportion of asthmatic children who require 800 µg/day of inhaled budesonideinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.1 20062006-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000100008es10.4067/S0034-98872006000100008
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Adrenal cortex function tests Asthma Budesonide Hydrocortisone
spellingShingle	Adrenal cortex function tests Asthma Budesonide Hydrocortisone Milinarsky T,Aída Fischer G,Sylvia Giadrosich R,Vinka Lezana S,Viviana Torres C,María Teresa Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos
description	Background: The use of inhaled steroids is common in the treatment of bronchial asthma in children. Aim: To assess adrenocortical function in children with severe asthma receiving inhaled budesonide for six or more months. Material and methods: Children with severe asthma that required 800 µg/day or more of inhaled budesonide and that did not required systemic steroids for more than six days in the last four months to control their disease, were studied. Serum cortisol was measured one hour after administration of 0.25 mg of ACTH (Cosyntropin®) intravenously. The test was considered normal if post stimulation serum cortisol was over 18 µg/ml. Results: Twenty children (aged 5 to 14 years, 15 males), were studied. The stimulation test was normal in 17 children. Conclusions: Alterations in adrenal function are present in a small proportion of asthmatic children who require 800 µg/day of inhaled budesonide
author	Milinarsky T,Aída Fischer G,Sylvia Giadrosich R,Vinka Lezana S,Viviana Torres C,María Teresa
author_facet	Milinarsky T,Aída Fischer G,Sylvia Giadrosich R,Vinka Lezana S,Viviana Torres C,María Teresa
author_sort	Milinarsky T,Aída
title	Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos
title_short	Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos
title_full	Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos
title_fullStr	Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos
title_full_unstemmed	Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos
title_sort	efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos
publisher	Sociedad Médica de Santiago
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000100008
work_keys_str_mv	AT milinarskytaida efectodedosisaltasdebudesonidayfuncionsuprarrenaldeninosasmaticosseveros AT fischergsylvia efectodedosisaltasdebudesonidayfuncionsuprarrenaldeninosasmaticosseveros AT giadrosichrvinka efectodedosisaltasdebudesonidayfuncionsuprarrenaldeninosasmaticosseveros AT lezanasviviana efectodedosisaltasdebudesonidayfuncionsuprarrenaldeninosasmaticosseveros AT torrescmariateresa efectodedosisaltasdebudesonidayfuncionsuprarrenaldeninosasmaticosseveros
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Efecto de dosis altas de budesonida y función suprarrenal de niños asmáticos severos

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