Estrés oxidativo, prooxidantes y enfermedad de Crohn

The frequency of Crohn disease shows a significant increase in the last century. Affected patients show a misbalance between production of free radicals and anti oxidant defenses. Thus, one of the increasingly accepted htypotheses to explain the origin of this disease, is the oxidative stress that o...

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Autores principales:	Tapia S,Alexis, Araya M.,Magdalena
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2006
Materias:	Crohn disease Inflammatory bowel diseases Oxidative stress Reactive oxygen species
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000100014
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spelling	oai:scielo:S0034-988720060001000142006-03-08Estrés oxidativo, prooxidantes y enfermedad de CrohnTapia S,AlexisAraya M.,Magdalena Crohn disease Inflammatory bowel diseases Oxidative stress Reactive oxygen species The frequency of Crohn disease shows a significant increase in the last century. Affected patients show a misbalance between production of free radicals and anti oxidant defenses. Thus, one of the increasingly accepted htypotheses to explain the origin of this disease, is the oxidative stress that occurs in the intestinal mucosa. Dietary factors including self administered vitamin and mineral supplemets may play a role, especially when they contain excessive amounts of iron and copper, known for their prooxidant capacities. Unfortunately, little is known about how these metals may influence the antioxidant defenses in the intestinal mucosa. This article reviews the literature on the why and how these elements may act on individuals susceptible to develop Crohm disease, including the evidence supporting the hypothesis that oxidative stress in the intestinal mucosa is an important pathogenetic factorinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.1 20062006-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000100014es10.4067/S0034-98872006000100014
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Crohn disease Inflammatory bowel diseases Oxidative stress Reactive oxygen species
spellingShingle	Crohn disease Inflammatory bowel diseases Oxidative stress Reactive oxygen species Tapia S,Alexis Araya M.,Magdalena Estrés oxidativo, prooxidantes y enfermedad de Crohn
description	The frequency of Crohn disease shows a significant increase in the last century. Affected patients show a misbalance between production of free radicals and anti oxidant defenses. Thus, one of the increasingly accepted htypotheses to explain the origin of this disease, is the oxidative stress that occurs in the intestinal mucosa. Dietary factors including self administered vitamin and mineral supplemets may play a role, especially when they contain excessive amounts of iron and copper, known for their prooxidant capacities. Unfortunately, little is known about how these metals may influence the antioxidant defenses in the intestinal mucosa. This article reviews the literature on the why and how these elements may act on individuals susceptible to develop Crohm disease, including the evidence supporting the hypothesis that oxidative stress in the intestinal mucosa is an important pathogenetic factor
author	Tapia S,Alexis Araya M.,Magdalena
author_facet	Tapia S,Alexis Araya M.,Magdalena
author_sort	Tapia S,Alexis
title	Estrés oxidativo, prooxidantes y enfermedad de Crohn
title_short	Estrés oxidativo, prooxidantes y enfermedad de Crohn
title_full	Estrés oxidativo, prooxidantes y enfermedad de Crohn
title_fullStr	Estrés oxidativo, prooxidantes y enfermedad de Crohn
title_full_unstemmed	Estrés oxidativo, prooxidantes y enfermedad de Crohn
title_sort	estrés oxidativo, prooxidantes y enfermedad de crohn
publisher	Sociedad Médica de Santiago
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000100014
work_keys_str_mv	AT tapiasalexis estresoxidativoprooxidantesyenfermedaddecrohn AT arayammagdalena estresoxidativoprooxidantesyenfermedaddecrohn
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Estrés oxidativo, prooxidantes y enfermedad de Crohn

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