Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómico

Background: The seroprevalence of antibodies against hepatitis A virus (HAV) is decreasing in many Latin American countries, along with improvements in sanitary standards. However, there is no information available about low socioeconomic status (LSE) populations. Aim: To assess the evolution of hep...

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Autores principales:	Ibarra V,Humberto, Riedemann G,Stella, Toledo A,Claudio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2006
Materias:	Hepatitis A Hepatitis A antibodies Hepatitis E Hepatitis, viral, human
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000200001
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spelling	oai:scielo:S0034-988720060002000012006-03-17Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómicoIbarra V,HumbertoRiedemann G,StellaToledo A,Claudio Hepatitis A Hepatitis A antibodies Hepatitis E Hepatitis, viral, human Background: The seroprevalence of antibodies against hepatitis A virus (HAV) is decreasing in many Latin American countries, along with improvements in sanitary standards. However, there is no information available about low socioeconomic status (LSE) populations. Aim: To assess the evolution of hepatitis A and E virus antibodies in a cohort of LSE Chilean children. Material and methods: One hundred sixty eight children aged four years, 97 males, coming from public primary care clinics, were studied. Two blood samples were obtained with an interval of one year. Anti-HAV and anti-hepatitis E virus (HEV) antibodies, were detected by ELISA using Abbott kits. Results: Anti-HAV was positive in 19 children (11.3%). After one year of follow-up, only 10 children had sustained reactivity (52.6%). Fourteen children, initially negative, became positive during the follow up (9.4%). Antibody titers to HAV were significantly higher in samples that remained positive, compared with those that lost reactivity. Anti-HEV was found positive in two children (1.2%). One remained positive and the other became negative. Conclusions: In this cohort of LSE Chilean children, the prevalence to antibodies against HAV and HEV is low. Follow-up detected loss of reactivity to HAV in nearly one half of the children, probably related to lower antibody levelsinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.2 20062006-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000200001es10.4067/S0034-98872006000200001
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Hepatitis A Hepatitis A antibodies Hepatitis E Hepatitis, viral, human
spellingShingle	Hepatitis A Hepatitis A antibodies Hepatitis E Hepatitis, viral, human Ibarra V,Humberto Riedemann G,Stella Toledo A,Claudio Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómico
description	Background: The seroprevalence of antibodies against hepatitis A virus (HAV) is decreasing in many Latin American countries, along with improvements in sanitary standards. However, there is no information available about low socioeconomic status (LSE) populations. Aim: To assess the evolution of hepatitis A and E virus antibodies in a cohort of LSE Chilean children. Material and methods: One hundred sixty eight children aged four years, 97 males, coming from public primary care clinics, were studied. Two blood samples were obtained with an interval of one year. Anti-HAV and anti-hepatitis E virus (HEV) antibodies, were detected by ELISA using Abbott kits. Results: Anti-HAV was positive in 19 children (11.3%). After one year of follow-up, only 10 children had sustained reactivity (52.6%). Fourteen children, initially negative, became positive during the follow up (9.4%). Antibody titers to HAV were significantly higher in samples that remained positive, compared with those that lost reactivity. Anti-HEV was found positive in two children (1.2%). One remained positive and the other became negative. Conclusions: In this cohort of LSE Chilean children, the prevalence to antibodies against HAV and HEV is low. Follow-up detected loss of reactivity to HAV in nearly one half of the children, probably related to lower antibody levels
author	Ibarra V,Humberto Riedemann G,Stella Toledo A,Claudio
author_facet	Ibarra V,Humberto Riedemann G,Stella Toledo A,Claudio
author_sort	Ibarra V,Humberto
title	Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómico
title_short	Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómico
title_full	Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómico
title_fullStr	Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómico
title_full_unstemmed	Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómico
title_sort	seguimientos de anticuerpos contra hepatitis a y e en una cohorte de niños de bajo nivel socioeconómico
publisher	Sociedad Médica de Santiago
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000200001
work_keys_str_mv	AT ibarravhumberto seguimientosdeanticuerposcontrahepatitisayeenunacohortedeninosdebajonivelsocioeconomico AT riedemanngstella seguimientosdeanticuerposcontrahepatitisayeenunacohortedeninosdebajonivelsocioeconomico AT toledoaclaudio seguimientosdeanticuerposcontrahepatitisayeenunacohortedeninosdebajonivelsocioeconomico
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Seguimientos de anticuerpos contra hepatitis A y E en una cohorte de niños de bajo nivel socioeconómico

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