Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case
Lambert-Eaton myasthenic syndrome (LEMS) is an autoinmune idiopathic or paraneoplastic syndrome producing antibodies agaisnt presynaptic voltage calcium channels. The clinical features of patients with LEMS are muscle weakness and autonomic dysfunction. We report a 40 years old man with a four years...
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Sociedad Médica de Santiago
2006
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oai:scielo:S0034-988720060002000132006-03-17Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one caseGuevara O,CarlosPedraza C,LuisIdiáquez C,JuanDelgado M,Marcela Lambert-Eaton Myasthenic syndrome Lambert-Eaton myasthenic syndrome (LEMS) is an autoinmune idiopathic or paraneoplastic syndrome producing antibodies agaisnt presynaptic voltage calcium channels. The clinical features of patients with LEMS are muscle weakness and autonomic dysfunction. We report a 40 years old man with a four years history of proximal weakness, absent tendon reflexes and dry mouth. The diagnosis was confirmed by characteristic electromyographic findings, showing a low-amplitude muscle response that increased dramatically after activation. Circulating antibodies to voltage-gated calcium channel were present. The search for malignant tumors was negative. The patient was treated with prednisone and azathioprine and after four months, he was able to walk and signs of autonomic dysfunction started to subsideinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.2 20062006-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000200013es10.4067/S0034-98872006000200013 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Lambert-Eaton Myasthenic syndrome |
spellingShingle |
Lambert-Eaton Myasthenic syndrome Guevara O,Carlos Pedraza C,Luis Idiáquez C,Juan Delgado M,Marcela Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case |
description |
Lambert-Eaton myasthenic syndrome (LEMS) is an autoinmune idiopathic or paraneoplastic syndrome producing antibodies agaisnt presynaptic voltage calcium channels. The clinical features of patients with LEMS are muscle weakness and autonomic dysfunction. We report a 40 years old man with a four years history of proximal weakness, absent tendon reflexes and dry mouth. The diagnosis was confirmed by characteristic electromyographic findings, showing a low-amplitude muscle response that increased dramatically after activation. Circulating antibodies to voltage-gated calcium channel were present. The search for malignant tumors was negative. The patient was treated with prednisone and azathioprine and after four months, he was able to walk and signs of autonomic dysfunction started to subside |
author |
Guevara O,Carlos Pedraza C,Luis Idiáquez C,Juan Delgado M,Marcela |
author_facet |
Guevara O,Carlos Pedraza C,Luis Idiáquez C,Juan Delgado M,Marcela |
author_sort |
Guevara O,Carlos |
title |
Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case |
title_short |
Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case |
title_full |
Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case |
title_fullStr |
Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case |
title_full_unstemmed |
Síndrome miasteniforme de Lambert-Eaton idiopático: Report of one case |
title_sort |
síndrome miasteniforme de lambert-eaton idiopático: report of one case |
publisher |
Sociedad Médica de Santiago |
publishDate |
2006 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000200013 |
work_keys_str_mv |
AT guevaraocarlos sindromemiasteniformedelamberteatonidiopaticoreportofonecase AT pedrazacluis sindromemiasteniformedelamberteatonidiopaticoreportofonecase AT idiaquezcjuan sindromemiasteniformedelamberteatonidiopaticoreportofonecase AT delgadommarcela sindromemiasteniformedelamberteatonidiopaticoreportofonecase |
_version_ |
1718436247112777728 |