Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un caso

Neurological manifestations, secondary to perfusion problems, vasogenic edema or small infarcts, are common in thrombotic purpura. Moreover, they are the first symptoms of the disease in 50% of patients. We report a 50 year-old woman who presented with focal intermittent neurological signs with apha...

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Autores principales:	Delgado D,Carolina, Flores P,Claudio, Silva R,Carlos
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2006
Materias:	Brain infarction Magnetic resonance imaging Purpura, thrombocytopenic
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000300013
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spelling	oai:scielo:S0034-988720060003000132006-05-02Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un casoDelgado D,CarolinaFlores P,ClaudioSilva R,Carlos Brain infarction Magnetic resonance imaging Purpura, thrombocytopenic Neurological manifestations, secondary to perfusion problems, vasogenic edema or small infarcts, are common in thrombotic purpura. Moreover, they are the first symptoms of the disease in 50% of patients. We report a 50 year-old woman who presented with focal intermittent neurological signs with aphasia and right hemiparesis, who then developed progressive impairment of consciousness with stupor and generalized tonic-clonic seizures. Despite the severe neurological impairment, first neuroimaging studies were normal. A second magnetic resonance imaging showed small cortical infarcts, that were visible only with the technique of diffusion weighted imaging. The standard electroencephalograms showed focal left temporal slowing and low voltage first and then diffuse slowing accordind to the clinical condition of the patients. She was treated with plasmapheresis and had a partial neurological recovery at the fifth day, but died at the twelfth day of therapyinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.3 20062006-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000300013es10.4067/S0034-98872006000300013
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Brain infarction Magnetic resonance imaging Purpura, thrombocytopenic
spellingShingle	Brain infarction Magnetic resonance imaging Purpura, thrombocytopenic Delgado D,Carolina Flores P,Claudio Silva R,Carlos Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un caso
description	Neurological manifestations, secondary to perfusion problems, vasogenic edema or small infarcts, are common in thrombotic purpura. Moreover, they are the first symptoms of the disease in 50% of patients. We report a 50 year-old woman who presented with focal intermittent neurological signs with aphasia and right hemiparesis, who then developed progressive impairment of consciousness with stupor and generalized tonic-clonic seizures. Despite the severe neurological impairment, first neuroimaging studies were normal. A second magnetic resonance imaging showed small cortical infarcts, that were visible only with the technique of diffusion weighted imaging. The standard electroencephalograms showed focal left temporal slowing and low voltage first and then diffuse slowing accordind to the clinical condition of the patients. She was treated with plasmapheresis and had a partial neurological recovery at the fifth day, but died at the twelfth day of therapy
author	Delgado D,Carolina Flores P,Claudio Silva R,Carlos
author_facet	Delgado D,Carolina Flores P,Claudio Silva R,Carlos
author_sort	Delgado D,Carolina
title	Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un caso
title_short	Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un caso
title_full	Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un caso
title_fullStr	Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un caso
title_full_unstemmed	Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un caso
title_sort	aspectos neurológicos del púrpura trombótico trombocitopénico: presentación de un caso
publisher	Sociedad Médica de Santiago
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000300013
work_keys_str_mv	AT delgadodcarolina aspectosneurologicosdelpurpuratromboticotrombocitopenicopresentaciondeuncaso AT florespclaudio aspectosneurologicosdelpurpuratromboticotrombocitopenicopresentaciondeuncaso AT silvarcarlos aspectosneurologicosdelpurpuratromboticotrombocitopenicopresentaciondeuncaso
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Aspectos neurológicos del púrpura trombótico trombocitopénico: Presentación de un caso

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