Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de tronco

Background: Anoxic-ischemic coma has a poor outcome with a high rate of mortality and morbidity. Therefore, clinical predictors of prognosis are needed for therapeutic decision-making. Patients and methods: Prospective analysis of 46 patients, 31 male, age range 19-85 years, with anoxic-ischemic com...

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Autores principales:	Lay-Son R,Luis, Varas F,Patricio
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2006
Materias:	Brain ischemia Brain stem Coma Hypoxia, brain
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400006
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spelling	oai:scielo:S0034-988720060004000062014-01-23Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de troncoLay-Son R,LuisVaras F,Patricio Brain ischemia Brain stem Coma Hypoxia, brain Background: Anoxic-ischemic coma has a poor outcome with a high rate of mortality and morbidity. Therefore, clinical predictors of prognosis are needed for therapeutic decision-making. Patients and methods: Prospective analysis of 46 patients, 31 male, age range 19-85 years, with anoxic-ischemic coma following cardiac arrest. All the patients included in our study remained comatose with a Glasgow Coma Scale (GCS) score of six or less points, after their stabilization in the Intensive Care Unit. They were evaluated clinically using the pupillary light reflex, corneal reflex and vestibulo-ocular reflex testing, induced by caloric stimulation with cold water. Survival was evaluated using life tables. All patients were followed until the thirtieth day after the anoxic-ischemic event. Results: Thirty five patients (76%) died within the next twenty-nine days, 8 patients (18%) reached the vegetative state, 2 patients (4%) achieved a recovery with disability, and only 1 patient (2%) was discharged without sequelae. One day, five and 30 days survival rates were 89, 53 and 29%, respectively. The abolition of all brainstem reflexes was not a predictor of mortality. Conclusion: Thirty day survival in this group of patients was 29% and the absence of brainstem reflexes was not a predictor of mortalityinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.4 20062006-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400006es10.4067/S0034-98872006000400006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Brain ischemia Brain stem Coma Hypoxia, brain
spellingShingle	Brain ischemia Brain stem Coma Hypoxia, brain Lay-Son R,Luis Varas F,Patricio Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de tronco
description	Background: Anoxic-ischemic coma has a poor outcome with a high rate of mortality and morbidity. Therefore, clinical predictors of prognosis are needed for therapeutic decision-making. Patients and methods: Prospective analysis of 46 patients, 31 male, age range 19-85 years, with anoxic-ischemic coma following cardiac arrest. All the patients included in our study remained comatose with a Glasgow Coma Scale (GCS) score of six or less points, after their stabilization in the Intensive Care Unit. They were evaluated clinically using the pupillary light reflex, corneal reflex and vestibulo-ocular reflex testing, induced by caloric stimulation with cold water. Survival was evaluated using life tables. All patients were followed until the thirtieth day after the anoxic-ischemic event. Results: Thirty five patients (76%) died within the next twenty-nine days, 8 patients (18%) reached the vegetative state, 2 patients (4%) achieved a recovery with disability, and only 1 patient (2%) was discharged without sequelae. One day, five and 30 days survival rates were 89, 53 and 29%, respectively. The abolition of all brainstem reflexes was not a predictor of mortality. Conclusion: Thirty day survival in this group of patients was 29% and the absence of brainstem reflexes was not a predictor of mortality
author	Lay-Son R,Luis Varas F,Patricio
author_facet	Lay-Son R,Luis Varas F,Patricio
author_sort	Lay-Son R,Luis
title	Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de tronco
title_short	Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de tronco
title_full	Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de tronco
title_fullStr	Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de tronco
title_full_unstemmed	Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de tronco
title_sort	coma anóxico-isquémico en 46 pacientes: evolución a treinta días y su relación con los reflejos de tronco
publisher	Sociedad Médica de Santiago
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400006
work_keys_str_mv	AT laysonrluis comaanoxicoisquemicoen46pacientesevolucionatreintadiasysurelacionconlosreflejosdetronco AT varasfpatricio comaanoxicoisquemicoen46pacientesevolucionatreintadiasysurelacionconlosreflejosdetronco
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Coma anóxico-isquémico en 46 pacientes: Evolución a treinta días y su relación con los reflejos de tronco

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