Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares

Background: Aspirative pleuropulmonary infections are usually caused by anaerobic flora of the mouth, mainly Prevotella, Fusobacterium and Peptostreptococcus spp. Penicillin in high doses is the traditional treatment for this type of infections but the rising resistance developed in recent years has...

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Autores principales:	Soler V,Tamara, Salamanca F,Lucía, Molina,Eliana
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2006
Materias:	Anti-bacterial agents bacteria, anaerobic Drug-resistance, microbial Prevotella
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400009
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spelling	oai:scielo:S0034-988720060004000092014-01-23Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonaresSoler V,TamaraSalamanca F,LucíaMolina,Eliana Anti-bacterial agents bacteria, anaerobic Drug-resistance, microbial Prevotella Background: Aspirative pleuropulmonary infections are usually caused by anaerobic flora of the mouth, mainly Prevotella, Fusobacterium and Peptostreptococcus spp. Penicillin in high doses is the traditional treatment for this type of infections but the rising resistance developed in recent years has induced the empiric use of clindamycin, increasing treatment costs. Aim: To study antimicrobial susceptibility of anaerobic bacteria isolated from pleuropulmonary infections. Material and methods: Thirty two strains obtained from bronchoalveolar lavage and 15 strains isolated from pleural effusions between 2000 and 2002, were studied. The phenotype of strains was identified using the semiautomated API 20 A method and their susceptibility to penicillin (PNC), clindamycin (CM) and chloramphenicol (CAF) was tested using the E test methods. Results: All the strains were susceptible to CAF, 95% to CM and 74.4% to PNC. The predominant genus was Prevotella, which also exhibited the higher resistance. Conclusions: As CM and CAF are active "in vitro", high rates of clinical response should be expected. In contrast, PNC is less effective, especially against pigmented Prevotellainfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.4 20062006-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400009es10.4067/S0034-98872006000400009
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Anti-bacterial agents bacteria, anaerobic Drug-resistance, microbial Prevotella
spellingShingle	Anti-bacterial agents bacteria, anaerobic Drug-resistance, microbial Prevotella Soler V,Tamara Salamanca F,Lucía Molina,Eliana Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares
description	Background: Aspirative pleuropulmonary infections are usually caused by anaerobic flora of the mouth, mainly Prevotella, Fusobacterium and Peptostreptococcus spp. Penicillin in high doses is the traditional treatment for this type of infections but the rising resistance developed in recent years has induced the empiric use of clindamycin, increasing treatment costs. Aim: To study antimicrobial susceptibility of anaerobic bacteria isolated from pleuropulmonary infections. Material and methods: Thirty two strains obtained from bronchoalveolar lavage and 15 strains isolated from pleural effusions between 2000 and 2002, were studied. The phenotype of strains was identified using the semiautomated API 20 A method and their susceptibility to penicillin (PNC), clindamycin (CM) and chloramphenicol (CAF) was tested using the E test methods. Results: All the strains were susceptible to CAF, 95% to CM and 74.4% to PNC. The predominant genus was Prevotella, which also exhibited the higher resistance. Conclusions: As CM and CAF are active "in vitro", high rates of clinical response should be expected. In contrast, PNC is less effective, especially against pigmented Prevotella
author	Soler V,Tamara Salamanca F,Lucía Molina,Eliana
author_facet	Soler V,Tamara Salamanca F,Lucía Molina,Eliana
author_sort	Soler V,Tamara
title	Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares
title_short	Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares
title_full	Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares
title_fullStr	Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares
title_full_unstemmed	Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares
title_sort	susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares
publisher	Sociedad Médica de Santiago
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400009
work_keys_str_mv	AT solervtamara susceptibilidadinvitrodebacteriasanaerobicaseninfeccionespleuropulmonares AT salamancaflucia susceptibilidadinvitrodebacteriasanaerobicaseninfeccionespleuropulmonares AT molinaeliana susceptibilidadinvitrodebacteriasanaerobicaseninfeccionespleuropulmonares
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Susceptibilidad in vitro de bacterias anaeróbicas en infecciones pleuropulmonares

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