Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases
Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis is an uncommon complication of the use of propylthiouracil. When it occurs, it affects multiple organs as any systemic vasculitis. We report three females and one male, aged 30, 40, 43 and 41 years respectively, that after a lapse of 12...
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Sociedad Médica de Santiago
2006
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oai:scielo:S0034-988720060004000112014-01-23Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four casesHidalgo V,SoledadSilva A,PaulinaUndurraga S,FernandaSoto I,NéstorMarinovic M,María Angélica Antibodies, antineutrophil cytoplasmic Propylthiouracil Vasculitis Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis is an uncommon complication of the use of propylthiouracil. When it occurs, it affects multiple organs as any systemic vasculitis. We report three females and one male, aged 30, 40, 43 and 41 years respectively, that after a lapse of 12 to 28 months of propylthiouracil use, presented clinical signs of vasculitis. All had high titers of ANCA against myeloperoxidase. In three patients, a skin biopsy confirmed the diagnosis. The condition subsided when propylthiouracil was discontinued, but one female patient required the use of prednisoneinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.4 20062006-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400011es10.4067/S0034-98872006000400011 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Antibodies, antineutrophil cytoplasmic Propylthiouracil Vasculitis |
spellingShingle |
Antibodies, antineutrophil cytoplasmic Propylthiouracil Vasculitis Hidalgo V,Soledad Silva A,Paulina Undurraga S,Fernanda Soto I,Néstor Marinovic M,María Angélica Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases |
description |
Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis is an uncommon complication of the use of propylthiouracil. When it occurs, it affects multiple organs as any systemic vasculitis. We report three females and one male, aged 30, 40, 43 and 41 years respectively, that after a lapse of 12 to 28 months of propylthiouracil use, presented clinical signs of vasculitis. All had high titers of ANCA against myeloperoxidase. In three patients, a skin biopsy confirmed the diagnosis. The condition subsided when propylthiouracil was discontinued, but one female patient required the use of prednisone |
author |
Hidalgo V,Soledad Silva A,Paulina Undurraga S,Fernanda Soto I,Néstor Marinovic M,María Angélica |
author_facet |
Hidalgo V,Soledad Silva A,Paulina Undurraga S,Fernanda Soto I,Néstor Marinovic M,María Angélica |
author_sort |
Hidalgo V,Soledad |
title |
Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases |
title_short |
Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases |
title_full |
Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases |
title_fullStr |
Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases |
title_full_unstemmed |
Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases |
title_sort |
vasculitis anca-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: report of four cases |
publisher |
Sociedad Médica de Santiago |
publishDate |
2006 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400011 |
work_keys_str_mv |
AT hidalgovsoledad vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases AT silvaapaulina vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases AT undurragasfernanda vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases AT sotoinestor vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases AT marinovicmmariaangelica vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases |
_version_ |
1718436256747094016 |