Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases

Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis is an uncommon complication of the use of propylthiouracil. When it occurs, it affects multiple organs as any systemic vasculitis. We report three females and one male, aged 30, 40, 43 and 41 years respectively, that after a lapse of 12...

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Autores principales: Hidalgo V,Soledad, Silva A,Paulina, Undurraga S,Fernanda, Soto I,Néstor, Marinovic M,María Angélica
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2006
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400011
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spelling oai:scielo:S0034-988720060004000112014-01-23Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four casesHidalgo V,SoledadSilva A,PaulinaUndurraga S,FernandaSoto I,NéstorMarinovic M,María Angélica Antibodies, antineutrophil cytoplasmic Propylthiouracil Vasculitis Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis is an uncommon complication of the use of propylthiouracil. When it occurs, it affects multiple organs as any systemic vasculitis. We report three females and one male, aged 30, 40, 43 and 41 years respectively, that after a lapse of 12 to 28 months of propylthiouracil use, presented clinical signs of vasculitis. All had high titers of ANCA against myeloperoxidase. In three patients, a skin biopsy confirmed the diagnosis. The condition subsided when propylthiouracil was discontinued, but one female patient required the use of prednisoneinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.4 20062006-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400011es10.4067/S0034-98872006000400011
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Antibodies, antineutrophil cytoplasmic
Propylthiouracil
Vasculitis
spellingShingle Antibodies, antineutrophil cytoplasmic
Propylthiouracil
Vasculitis
Hidalgo V,Soledad
Silva A,Paulina
Undurraga S,Fernanda
Soto I,Néstor
Marinovic M,María Angélica
Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases
description Antineutrophil cytoplasmic antibody (ANCA)-positive vasculitis is an uncommon complication of the use of propylthiouracil. When it occurs, it affects multiple organs as any systemic vasculitis. We report three females and one male, aged 30, 40, 43 and 41 years respectively, that after a lapse of 12 to 28 months of propylthiouracil use, presented clinical signs of vasculitis. All had high titers of ANCA against myeloperoxidase. In three patients, a skin biopsy confirmed the diagnosis. The condition subsided when propylthiouracil was discontinued, but one female patient required the use of prednisone
author Hidalgo V,Soledad
Silva A,Paulina
Undurraga S,Fernanda
Soto I,Néstor
Marinovic M,María Angélica
author_facet Hidalgo V,Soledad
Silva A,Paulina
Undurraga S,Fernanda
Soto I,Néstor
Marinovic M,María Angélica
author_sort Hidalgo V,Soledad
title Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases
title_short Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases
title_full Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases
title_fullStr Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases
title_full_unstemmed Vasculitis ANCA-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: Report of four cases
title_sort vasculitis anca-positivo en pacientes hipertiroideos usuarios de propiltiouracilo: report of four cases
publisher Sociedad Médica de Santiago
publishDate 2006
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000400011
work_keys_str_mv AT hidalgovsoledad vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases
AT silvaapaulina vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases
AT undurragasfernanda vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases
AT sotoinestor vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases
AT marinovicmmariaangelica vasculitisancapositivoenpacienteshipertiroideosusuariosdepropiltiouraciloreportoffourcases
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