Cáncer de vesícula biliar: Tendencia y distribución del riesgo en Chile

Background: Gallbladder cancer (GBC) is the first cause of death by cancer among Chilean women and mortality has not improved in the last 20 years. Aim: To study GBC mortality trend from 1985-2002, analyze risk differentials by age, sex, geographic region and accessibility to surgery. Material and M...

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Autores principales:	Andia K,Marcelo, Gederlini G,Alessandra, Ferreccio R,Catterina
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2006
Materias:	Cholecystectomy Gallbladder neoplasms Gallstones
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000500004
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spelling	oai:scielo:S0034-988720060005000042006-06-22Cáncer de vesícula biliar: Tendencia y distribución del riesgo en ChileAndia K,MarceloGederlini G,AlessandraFerreccio R,Catterina Cholecystectomy Gallbladder neoplasms Gallstones Background: Gallbladder cancer (GBC) is the first cause of death by cancer among Chilean women and mortality has not improved in the last 20 years. Aim: To study GBC mortality trend from 1985-2002, analyze risk differentials by age, sex, geographic region and accessibility to surgery. Material and Methods: Mortality data was obtained from death certificate databases. Population data was obtained from the census and biliary surgery information, from Ministry of Health registries. Standardized Mortality rates were based in the world population; trend was analyzed with point of change methods. Results: From 1985 to 2002, 27,183 GBC deaths occurred, 1,510 per year. The absolute number of deaths increased in 65% but standardized mortality rates remained unchanged at 11.3 per 100,000. These were higher among women than men (15.6 and 7.0, respectively, with a risk ratio of 2.2). Sex ratio peaked at ages 35-54 with risk ratio of 4.1. Death risk increased from North to South, peaking in poorer areas, especially in places with rural population and Mapuche ethnic admixture. Mortality appear to correlate with the rate of people waiting for gallbladder surgery, but not reaching statistical significance (r² 0.27, ns). Compared with other countries, Chile has a higher rate of GBC deaths in relation to its gross domestic product per capita. Conclusions: There is a high and persistent persistent risk for GBC in Chile, particularly among women, from the Southern regions where gallbladder surgery is insufficient for the needs, as reflected by the rates of people waiting for biliary surgery. GBC rates could be dropped by offering gallbladder surgery to everyone waiting for it and to those incident cases with gallstonesinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.5 20062006-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000500004es10.4067/S0034-98872006000500004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Cholecystectomy Gallbladder neoplasms Gallstones
spellingShingle	Cholecystectomy Gallbladder neoplasms Gallstones Andia K,Marcelo Gederlini G,Alessandra Ferreccio R,Catterina Cáncer de vesícula biliar: Tendencia y distribución del riesgo en Chile
description	Background: Gallbladder cancer (GBC) is the first cause of death by cancer among Chilean women and mortality has not improved in the last 20 years. Aim: To study GBC mortality trend from 1985-2002, analyze risk differentials by age, sex, geographic region and accessibility to surgery. Material and Methods: Mortality data was obtained from death certificate databases. Population data was obtained from the census and biliary surgery information, from Ministry of Health registries. Standardized Mortality rates were based in the world population; trend was analyzed with point of change methods. Results: From 1985 to 2002, 27,183 GBC deaths occurred, 1,510 per year. The absolute number of deaths increased in 65% but standardized mortality rates remained unchanged at 11.3 per 100,000. These were higher among women than men (15.6 and 7.0, respectively, with a risk ratio of 2.2). Sex ratio peaked at ages 35-54 with risk ratio of 4.1. Death risk increased from North to South, peaking in poorer areas, especially in places with rural population and Mapuche ethnic admixture. Mortality appear to correlate with the rate of people waiting for gallbladder surgery, but not reaching statistical significance (r² 0.27, ns). Compared with other countries, Chile has a higher rate of GBC deaths in relation to its gross domestic product per capita. Conclusions: There is a high and persistent persistent risk for GBC in Chile, particularly among women, from the Southern regions where gallbladder surgery is insufficient for the needs, as reflected by the rates of people waiting for biliary surgery. GBC rates could be dropped by offering gallbladder surgery to everyone waiting for it and to those incident cases with gallstones
author	Andia K,Marcelo Gederlini G,Alessandra Ferreccio R,Catterina
author_facet	Andia K,Marcelo Gederlini G,Alessandra Ferreccio R,Catterina
author_sort	Andia K,Marcelo
title	Cáncer de vesícula biliar: Tendencia y distribución del riesgo en Chile
title_short	Cáncer de vesícula biliar: Tendencia y distribución del riesgo en Chile
title_full	Cáncer de vesícula biliar: Tendencia y distribución del riesgo en Chile
title_fullStr	Cáncer de vesícula biliar: Tendencia y distribución del riesgo en Chile
title_full_unstemmed	Cáncer de vesícula biliar: Tendencia y distribución del riesgo en Chile
title_sort	cáncer de vesícula biliar: tendencia y distribución del riesgo en chile
publisher	Sociedad Médica de Santiago
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006000500004
work_keys_str_mv	AT andiakmarcelo cancerdevesiculabiliartendenciaydistribuciondelriesgoenchile AT gederlinigalessandra cancerdevesiculabiliartendenciaydistribuciondelriesgoenchile AT ferrecciorcatterina cancerdevesiculabiliartendenciaydistribuciondelriesgoenchile
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Cáncer de vesícula biliar: Tendencia y distribución del riesgo en Chile

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