Tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuibles

Background: Smoking is the main risk factor for Chronic Obstructive Pulmonary Disease (COPD), an important cause of morbidity and mortality. Aim: To estimate smoking attributable risk and population attributable risk in COPD patients attended in Public Health Services of Santiago. Materials and meth...

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Autores principales: Amigo C,Hugo, Erazo B,Marcia, Oyarzún G,Manuel, Bello S,Sergio, Peruga U,Armando
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2006
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006001000009
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spelling oai:scielo:S0034-988720060010000092006-12-28Tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuiblesAmigo C,HugoErazo B,MarciaOyarzún G,ManuelBello S,SergioPeruga U,Armando Pulmonary disease, chronic obstructive Smoking, Tobacco Background: Smoking is the main risk factor for Chronic Obstructive Pulmonary Disease (COPD), an important cause of morbidity and mortality. Aim: To estimate smoking attributable risk and population attributable risk in COPD patients attended in Public Health Services of Santiago. Materials and methods: A case control study matched by sex and age was carried out. Crude and adjusted attributable risks as well as population attributable risk were estimated, controlled by potential confounders and by interaction variables. Results: Mean ages for cases and controls were 68 and 67 years respectively. When compared to the control group, COPD patients had a higher smoking prevalence (at least 100 cigarettes in their life span: 89.7% vs 60.3%; p <0.01). Among COPD patients, heavy smokers proportion was 4 times higher than in controls, they smoked for more years (43 vs 31; p <0.01) and more cigarettes per day (18 vs 5; p <0.01). Adjusted attributable risk was 87% (95% Confidence Interval (CI): 63.7-94.8). If a patient smoked at least 100 cigarettes in his/her life span and this risk was 92.7% (CI: 82.4-96.9) for heavy smokers. Projecting this index to Santiago inhabitants, about 87,000 individuals older than 40 years would be suffering COPD due to smoking. Conclusions: This article confirms the strong association between smoking and COPD. Attributable risks are high and significant, even when they are adjusted by confounding variables. Women had a higher risk than men, at lower levels of tobacco consumptioninfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.10 20062006-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006001000009es10.4067/S0034-98872006001000009
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Pulmonary disease, chronic obstructive
Smoking, Tobacco
spellingShingle Pulmonary disease, chronic obstructive
Smoking, Tobacco
Amigo C,Hugo
Erazo B,Marcia
Oyarzún G,Manuel
Bello S,Sergio
Peruga U,Armando
Tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuibles
description Background: Smoking is the main risk factor for Chronic Obstructive Pulmonary Disease (COPD), an important cause of morbidity and mortality. Aim: To estimate smoking attributable risk and population attributable risk in COPD patients attended in Public Health Services of Santiago. Materials and methods: A case control study matched by sex and age was carried out. Crude and adjusted attributable risks as well as population attributable risk were estimated, controlled by potential confounders and by interaction variables. Results: Mean ages for cases and controls were 68 and 67 years respectively. When compared to the control group, COPD patients had a higher smoking prevalence (at least 100 cigarettes in their life span: 89.7% vs 60.3%; p <0.01). Among COPD patients, heavy smokers proportion was 4 times higher than in controls, they smoked for more years (43 vs 31; p <0.01) and more cigarettes per day (18 vs 5; p <0.01). Adjusted attributable risk was 87% (95% Confidence Interval (CI): 63.7-94.8). If a patient smoked at least 100 cigarettes in his/her life span and this risk was 92.7% (CI: 82.4-96.9) for heavy smokers. Projecting this index to Santiago inhabitants, about 87,000 individuals older than 40 years would be suffering COPD due to smoking. Conclusions: This article confirms the strong association between smoking and COPD. Attributable risks are high and significant, even when they are adjusted by confounding variables. Women had a higher risk than men, at lower levels of tobacco consumption
author Amigo C,Hugo
Erazo B,Marcia
Oyarzún G,Manuel
Bello S,Sergio
Peruga U,Armando
author_facet Amigo C,Hugo
Erazo B,Marcia
Oyarzún G,Manuel
Bello S,Sergio
Peruga U,Armando
author_sort Amigo C,Hugo
title Tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuibles
title_short Tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuibles
title_full Tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuibles
title_fullStr Tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuibles
title_full_unstemmed Tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuibles
title_sort tabaquismo y enfermedad pulmonar obstructiva crónica: determinación de fracciones atribuibles
publisher Sociedad Médica de Santiago
publishDate 2006
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006001000009
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