Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad

Background: Severity assessment of community-acquired pneumonia (CAP) patients allows the clinician to decide the place of management and guide empirical antimicrobial treatment. Aim: To assess admission prognostic factors and outcome of CAP in immunocompetent adult patients hospitalized in 21 medic...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Gil D,Rodrigo, Undurraga P,Álvaro, Saldías P,Fernando, Jiménez P,Patricio, Barros M,Manuel
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2006
Materias:	Anti-bacterial agents Pneumonia, community-acquired Prognosis Treatment outcome
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006001100002
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872006001100002
record_format	dspace
spelling	oai:scielo:S0034-988720060011000022014-01-24Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidadGil D,RodrigoUndurraga P,ÁlvaroSaldías P,FernandoJiménez P,PatricioBarros M,Manuel Anti-bacterial agents Pneumonia, community-acquired Prognosis Treatment outcome Background: Severity assessment of community-acquired pneumonia (CAP) patients allows the clinician to decide the place of management and guide empirical antimicrobial treatment. Aim: To assess admission prognostic factors and outcome of CAP in immunocompetent adult patients hospitalized in 21 medical centers in Chile. Material and methods: Prospective evaluation of non immunocompromised adults with CAP admitted to 21 Chilean hospitals between July and August, 1999. All patients were assessed on admission and followed until discharge or death. Results: During the study period, 1,194 patients (aged 68±17 years, 573 males) were evaluated. Seventy two percent had an underlying disease (especially chronic cardiovascular, neurological, respiratory diseases and diabetes mellitus), and 90% were treated with ß-lactamic agents (especially a third generation cephalosporin or penicillin). Mean hospital length of stay was 11±9 days, 10% were admitted to Intermediate Care or Intensive Care Units (ICU), 6% were mechanically ventilated and in-hospital mortality was 15.7%. Admission prognostic factors associated with hospital mortality were: advanced age, male gender, presence of comorbidity (chronic cardiovascular, renal, neurological and hepatic disease), undernutrition, suspicion of aspiration, altered mental status, low blood pressure, tachypnea, absence of fever, high blood urea nitrogen, multilobar radiographic pulmonary infiltrates, high risk categories from Chilean Respiratory Diseases Society Consensus, admission to Intermediate Care Units or ICU, and mechanical ventilation. In the multivariate analysis, prognostic factors associated with high hospital mortality were: mental confusion, high blood urea nitrogen, multilobar pneumonia, presence of comorbidity and absence of fever on admission. Conclusions: These results validate in Chile, findings from foreign studiesinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.134 n.11 20062006-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006001100002es10.4067/S0034-98872006001100002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Anti-bacterial agents Pneumonia, community-acquired Prognosis Treatment outcome
spellingShingle	Anti-bacterial agents Pneumonia, community-acquired Prognosis Treatment outcome Gil D,Rodrigo Undurraga P,Álvaro Saldías P,Fernando Jiménez P,Patricio Barros M,Manuel Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad
description	Background: Severity assessment of community-acquired pneumonia (CAP) patients allows the clinician to decide the place of management and guide empirical antimicrobial treatment. Aim: To assess admission prognostic factors and outcome of CAP in immunocompetent adult patients hospitalized in 21 medical centers in Chile. Material and methods: Prospective evaluation of non immunocompromised adults with CAP admitted to 21 Chilean hospitals between July and August, 1999. All patients were assessed on admission and followed until discharge or death. Results: During the study period, 1,194 patients (aged 68±17 years, 573 males) were evaluated. Seventy two percent had an underlying disease (especially chronic cardiovascular, neurological, respiratory diseases and diabetes mellitus), and 90% were treated with ß-lactamic agents (especially a third generation cephalosporin or penicillin). Mean hospital length of stay was 11±9 days, 10% were admitted to Intermediate Care or Intensive Care Units (ICU), 6% were mechanically ventilated and in-hospital mortality was 15.7%. Admission prognostic factors associated with hospital mortality were: advanced age, male gender, presence of comorbidity (chronic cardiovascular, renal, neurological and hepatic disease), undernutrition, suspicion of aspiration, altered mental status, low blood pressure, tachypnea, absence of fever, high blood urea nitrogen, multilobar radiographic pulmonary infiltrates, high risk categories from Chilean Respiratory Diseases Society Consensus, admission to Intermediate Care Units or ICU, and mechanical ventilation. In the multivariate analysis, prognostic factors associated with high hospital mortality were: mental confusion, high blood urea nitrogen, multilobar pneumonia, presence of comorbidity and absence of fever on admission. Conclusions: These results validate in Chile, findings from foreign studies
author	Gil D,Rodrigo Undurraga P,Álvaro Saldías P,Fernando Jiménez P,Patricio Barros M,Manuel
author_facet	Gil D,Rodrigo Undurraga P,Álvaro Saldías P,Fernando Jiménez P,Patricio Barros M,Manuel
author_sort	Gil D,Rodrigo
title	Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad
title_short	Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad
title_full	Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad
title_fullStr	Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad
title_full_unstemmed	Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad
title_sort	estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad
publisher	Sociedad Médica de Santiago
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872006001100002
work_keys_str_mv	AT gildrodrigo estudiomulticentricodefactorespronosticosenadultoshospitalizadosporneumoniaadquiridaenlacomunidad AT undurragapalvaro estudiomulticentricodefactorespronosticosenadultoshospitalizadosporneumoniaadquiridaenlacomunidad AT saldiaspfernando estudiomulticentricodefactorespronosticosenadultoshospitalizadosporneumoniaadquiridaenlacomunidad AT jimenezppatricio estudiomulticentricodefactorespronosticosenadultoshospitalizadosporneumoniaadquiridaenlacomunidad AT barrosmmanuel estudiomulticentricodefactorespronosticosenadultoshospitalizadosporneumoniaadquiridaenlacomunidad
_version_	1718436291216932864

Estudio multicéntrico de factores pronósticos en adultos hospitalizados por neumonía adquirida en la comunidad

Ejemplares similares