Cien años de la enfermedad de Alzheimer: La inmunoterapia ¿una esperanza?
In 1906 Alois Alzheimer, described the cerebral lesions characteristic of the disorder that received his name: senile plaques and neurofibrillary tangles. Alzheimer's disease (AD) is now, 100 years after, the most prevalent form of dementia in the world. The longer life expectancy and aging of...
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| Lenguaje: | Spanish / Castilian |
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Sociedad Médica de Santiago
2007
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oai:scielo:S0034-988720070001000152014-01-06Cien años de la enfermedad de Alzheimer: La inmunoterapia ¿una esperanza?Behrens P,María IsabelVergara E,Fernando Alzheimer disease Immunoglobulins, intravenous Positron-emission tomography Senile plaques In 1906 Alois Alzheimer, described the cerebral lesions characteristic of the disorder that received his name: senile plaques and neurofibrillary tangles. Alzheimer's disease (AD) is now, 100 years after, the most prevalent form of dementia in the world. The longer life expectancy and aging of the population renders it as a serious public health problem of the future. Urgent methods of diagnosis and treatment are required, since the definitive diagnosis of AD continues to be neuropathologic. In the last 30 years several drugs have been approved to retard the progression of the disease; however, there are still no curative or preventive treatments. Although still in experimentation, the visualization of amyloid deposition by positron emission tomography or magnetic resonance imaging will allow in vivo diagnosis of AD. In addition, experiments with the amyloid vaccine are still ongoing, and very recent data suggest that intravenous gammaglobulins may be beneficial and safe for the treatment of ADinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.1 20072007-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000100015es10.4067/S0034-98872007000100015 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
Spanish / Castilian |
| topic |
Alzheimer disease Immunoglobulins, intravenous Positron-emission tomography Senile plaques |
| spellingShingle |
Alzheimer disease Immunoglobulins, intravenous Positron-emission tomography Senile plaques Behrens P,María Isabel Vergara E,Fernando Cien años de la enfermedad de Alzheimer: La inmunoterapia ¿una esperanza? |
| description |
In 1906 Alois Alzheimer, described the cerebral lesions characteristic of the disorder that received his name: senile plaques and neurofibrillary tangles. Alzheimer's disease (AD) is now, 100 years after, the most prevalent form of dementia in the world. The longer life expectancy and aging of the population renders it as a serious public health problem of the future. Urgent methods of diagnosis and treatment are required, since the definitive diagnosis of AD continues to be neuropathologic. In the last 30 years several drugs have been approved to retard the progression of the disease; however, there are still no curative or preventive treatments. Although still in experimentation, the visualization of amyloid deposition by positron emission tomography or magnetic resonance imaging will allow in vivo diagnosis of AD. In addition, experiments with the amyloid vaccine are still ongoing, and very recent data suggest that intravenous gammaglobulins may be beneficial and safe for the treatment of AD |
| author |
Behrens P,María Isabel Vergara E,Fernando |
| author_facet |
Behrens P,María Isabel Vergara E,Fernando |
| author_sort |
Behrens P,María Isabel |
| title |
Cien años de la enfermedad de Alzheimer: La inmunoterapia ¿una esperanza? |
| title_short |
Cien años de la enfermedad de Alzheimer: La inmunoterapia ¿una esperanza? |
| title_full |
Cien años de la enfermedad de Alzheimer: La inmunoterapia ¿una esperanza? |
| title_fullStr |
Cien años de la enfermedad de Alzheimer: La inmunoterapia ¿una esperanza? |
| title_full_unstemmed |
Cien años de la enfermedad de Alzheimer: La inmunoterapia ¿una esperanza? |
| title_sort |
cien años de la enfermedad de alzheimer: la inmunoterapia ¿una esperanza? |
| publisher |
Sociedad Médica de Santiago |
| publishDate |
2007 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000100015 |
| work_keys_str_mv |
AT behrenspmariaisabel cienanosdelaenfermedaddealzheimerlainmunoterapiaunaesperanza AT vergaraefernando cienanosdelaenfermedaddealzheimerlainmunoterapiaunaesperanza |
| _version_ |
1718436303247245312 |