Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica

Background: S pneumoniae is the main cause of community-acquired pneumonia in the elderly, group that concentrates 95% of deaths. Aim: To assess the prevalence of nasal carriage of S pneumoniae in institutionalized elderly patients. Material and methods: One hundred eighteen institutionalized subjec...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Altuzarra H,Rogelio, Valenzuela B,M. Teresa, Trucco A,Olivia, Inostroza S,Jaime, Granata S,Paulo, Fleiderman V,José
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2007
Materias:	Aged Pneumococcal vaccines Streptococcus pneumoniae
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200003
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872007000200003
record_format	dspace
spelling	oai:scielo:S0034-988720070002000032007-03-28Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócicaAltuzarra H,RogelioValenzuela B,M. TeresaTrucco A,OliviaInostroza S,JaimeGranata S,PauloFleiderman V,José Aged Pneumococcal vaccines Streptococcus pneumoniae Background: S pneumoniae is the main cause of community-acquired pneumonia in the elderly, group that concentrates 95% of deaths. Aim: To assess the prevalence of nasal carriage of S pneumoniae in institutionalized elderly patients. Material and methods: One hundred eighteen institutionalized subjects aged over 60 years (65 males) were enrolled. Since they were also participating in a controlled protocol related to the immunogenicity of an anti-pneumococcal vaccine, our investigation was also blind and randomized. According to randomization, they received pneumococcal or tetanic vaccine. Nasal swab cultures were taken at the beginning of the trial and two months after vaccination. According to recommended methods, we identified S pneumoniae, the serotypes and their antimicrobial susceptibility. Results: In the first nasal sample, 16% of subjects were positive for S pneumoniae. The second sample was positive in 12%. Of the 33 isolated serotypes, 9.1% demonstrated intermediate resistance to penicillin and 3.3% were resistant to chloramphenicol. Conclusions: The study demonstrated a greater percentage of colonized patients than in the general population. The isolated serotypes are the same that cause invasive diseases in this age group, according to data of the Institute of Public Health of Chile. There were no differences in the percentage of colonization between subjects vaccinated against S pneumoniae and control groups, after two months of follow up. Isolated strains had a low resistance to penicillin. High level resistance was not observedinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.2 20072007-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200003es10.4067/S0034-98872007000200003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Aged Pneumococcal vaccines Streptococcus pneumoniae
spellingShingle	Aged Pneumococcal vaccines Streptococcus pneumoniae Altuzarra H,Rogelio Valenzuela B,M. Teresa Trucco A,Olivia Inostroza S,Jaime Granata S,Paulo Fleiderman V,José Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica
description	Background: S pneumoniae is the main cause of community-acquired pneumonia in the elderly, group that concentrates 95% of deaths. Aim: To assess the prevalence of nasal carriage of S pneumoniae in institutionalized elderly patients. Material and methods: One hundred eighteen institutionalized subjects aged over 60 years (65 males) were enrolled. Since they were also participating in a controlled protocol related to the immunogenicity of an anti-pneumococcal vaccine, our investigation was also blind and randomized. According to randomization, they received pneumococcal or tetanic vaccine. Nasal swab cultures were taken at the beginning of the trial and two months after vaccination. According to recommended methods, we identified S pneumoniae, the serotypes and their antimicrobial susceptibility. Results: In the first nasal sample, 16% of subjects were positive for S pneumoniae. The second sample was positive in 12%. Of the 33 isolated serotypes, 9.1% demonstrated intermediate resistance to penicillin and 3.3% were resistant to chloramphenicol. Conclusions: The study demonstrated a greater percentage of colonized patients than in the general population. The isolated serotypes are the same that cause invasive diseases in this age group, according to data of the Institute of Public Health of Chile. There were no differences in the percentage of colonization between subjects vaccinated against S pneumoniae and control groups, after two months of follow up. Isolated strains had a low resistance to penicillin. High level resistance was not observed
author	Altuzarra H,Rogelio Valenzuela B,M. Teresa Trucco A,Olivia Inostroza S,Jaime Granata S,Paulo Fleiderman V,José
author_facet	Altuzarra H,Rogelio Valenzuela B,M. Teresa Trucco A,Olivia Inostroza S,Jaime Granata S,Paulo Fleiderman V,José
author_sort	Altuzarra H,Rogelio
title	Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica
title_short	Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica
title_full	Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica
title_fullStr	Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica
title_full_unstemmed	Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica
title_sort	portación nasal de streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica
publisher	Sociedad Médica de Santiago
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200003
work_keys_str_mv	AT altuzarrahrogelio portacionnasaldestreptococcuspneumoniaeenadultomayorysurespuestafrentealavacunacionantineumococica AT valenzuelabmteresa portacionnasaldestreptococcuspneumoniaeenadultomayorysurespuestafrentealavacunacionantineumococica AT truccoaolivia portacionnasaldestreptococcuspneumoniaeenadultomayorysurespuestafrentealavacunacionantineumococica AT inostrozasjaime portacionnasaldestreptococcuspneumoniaeenadultomayorysurespuestafrentealavacunacionantineumococica AT granataspaulo portacionnasaldestreptococcuspneumoniaeenadultomayorysurespuestafrentealavacunacionantineumococica AT fleidermanvjose portacionnasaldestreptococcuspneumoniaeenadultomayorysurespuestafrentealavacunacionantineumococica
_version_	1718436305036115968

Portación nasal de Streptococcus pneumoniae en adulto mayor y su respuesta frente a la vacunación antineumocócica

Ejemplares similares