Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad

Background: In Chile between 1986 and 1998, the prevalence of obesity has increased from 4.6% to 24% in prepuberal and from 2.3% to 17% in puberal children. Aim: To assess the prevalence of metabolic syndrome (MS) in a sample of obese and overweight Chilean children. Patients and methods: Descriptiv...

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Autores principales:	Burrows A,Raquel, Leiva B,Laura, Weistaub,Gerardo, Ceballos S,Ximena, Gattas Z,Vivian, Lera M,Lydia, Albala B,Cecilia
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2007
Materias:	Infant overnutrition Metabolic syndrome X Obesity
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200005
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spelling	oai:scielo:S0034-988720070002000052007-03-28Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidadBurrows A,RaquelLeiva B,LauraWeistaub,GerardoCeballos S,XimenaGattas Z,VivianLera M,LydiaAlbala B,Cecilia Infant overnutrition Metabolic syndrome X Obesity Background: In Chile between 1986 and 1998, the prevalence of obesity has increased from 4.6% to 24% in prepuberal and from 2.3% to 17% in puberal children. Aim: To assess the prevalence of metabolic syndrome (MS) in a sample of obese and overweight Chilean children. Patients and methods: Descriptive study in 489 children (273 females), aged from 6 to 16 years, consulting in an obesity program. Body mass index, Tanner puberal development, waist circumference, blood pressure, fasting blood glucose, insulin and lipid levels were measured. Insulin sensitivity was calculated using the mathematical models QUICKI and HOMA. MS was diagnosed when three or more of the following criteria were met: a waist circumference over percentile 90, a blood pressure over percentile 90, serum triglycerides over 110 mg/dl, HDL cholesterol of less than 40 mg/dl or a fasting blood glucose level over 100 mg/dl. Results: MS was present in 4% of children with overweight and 30% of obese children. No differences in prevalence were observed for sex or puberal development. The most prevalent cardiovascular risk factors were abdominal obesity, present in 76% of the sample and high triclycerides levels in 39%. The less prevalent risk factor was a fasting blood glucose over 100 mg/dl in 3.7%. The risk for MS increased ten fold in children with severe obesity, compared with those with overweight. Those with abdominal obesity had a 17 times higher risk of MS. Basal insulin sensitivity was significantly associated with the number of cardiovascular risk factors and the presence of MS. Conclusions: In this sample of children, fat distribution and the severity of obesity were strong determinants of MS. Waist circumference had a higher impact on MS than body mass indexinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.2 20072007-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200005es10.4067/S0034-98872007000200005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Infant overnutrition Metabolic syndrome X Obesity
spellingShingle	Infant overnutrition Metabolic syndrome X Obesity Burrows A,Raquel Leiva B,Laura Weistaub,Gerardo Ceballos S,Ximena Gattas Z,Vivian Lera M,Lydia Albala B,Cecilia Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad
description	Background: In Chile between 1986 and 1998, the prevalence of obesity has increased from 4.6% to 24% in prepuberal and from 2.3% to 17% in puberal children. Aim: To assess the prevalence of metabolic syndrome (MS) in a sample of obese and overweight Chilean children. Patients and methods: Descriptive study in 489 children (273 females), aged from 6 to 16 years, consulting in an obesity program. Body mass index, Tanner puberal development, waist circumference, blood pressure, fasting blood glucose, insulin and lipid levels were measured. Insulin sensitivity was calculated using the mathematical models QUICKI and HOMA. MS was diagnosed when three or more of the following criteria were met: a waist circumference over percentile 90, a blood pressure over percentile 90, serum triglycerides over 110 mg/dl, HDL cholesterol of less than 40 mg/dl or a fasting blood glucose level over 100 mg/dl. Results: MS was present in 4% of children with overweight and 30% of obese children. No differences in prevalence were observed for sex or puberal development. The most prevalent cardiovascular risk factors were abdominal obesity, present in 76% of the sample and high triclycerides levels in 39%. The less prevalent risk factor was a fasting blood glucose over 100 mg/dl in 3.7%. The risk for MS increased ten fold in children with severe obesity, compared with those with overweight. Those with abdominal obesity had a 17 times higher risk of MS. Basal insulin sensitivity was significantly associated with the number of cardiovascular risk factors and the presence of MS. Conclusions: In this sample of children, fat distribution and the severity of obesity were strong determinants of MS. Waist circumference had a higher impact on MS than body mass index
author	Burrows A,Raquel Leiva B,Laura Weistaub,Gerardo Ceballos S,Ximena Gattas Z,Vivian Lera M,Lydia Albala B,Cecilia
author_facet	Burrows A,Raquel Leiva B,Laura Weistaub,Gerardo Ceballos S,Ximena Gattas Z,Vivian Lera M,Lydia Albala B,Cecilia
author_sort	Burrows A,Raquel
title	Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad
title_short	Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad
title_full	Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad
title_fullStr	Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad
title_full_unstemmed	Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad
title_sort	síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad
publisher	Sociedad Médica de Santiago
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200005
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Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad

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