Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposiciones

Background: During infancy, preventive, diagnostic and therapeutic efforts for Helicobacter pylori infection should be made. Aim: To evaluate non-invasive diagnostic methods such as stool antigen test (HpSA) and serum anti-H pylori antibody detection (IgG e IgA), compared to endoscopy-based invasive...

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Autores principales:	González F,Carmen Gloria, Serrano H,Carolina, Harris,Paul R
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2007
Materias:	Antibodies, bacterial Helicobacter pylori Immunoglobulins
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200006
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spelling	oai:scielo:S0034-988720070002000062007-03-28Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposicionesGonzález F,Carmen GloriaSerrano H,CarolinaHarris,Paul R Antibodies, bacterial Helicobacter pylori Immunoglobulins Background: During infancy, preventive, diagnostic and therapeutic efforts for Helicobacter pylori infection should be made. Aim: To evaluate non-invasive diagnostic methods such as stool antigen test (HpSA) and serum anti-H pylori antibody detection (IgG e IgA), compared to endoscopy-based invasive methods (histology and urease test) for the diagnosis of Helicobacter pylori infection. Patients and Methods: Thirty nine children (aged 3 to 14 years, 20 males) referred for upper gastrointestinal endoscopy, were studied. The gold standard to diagnose Helicobacter pylori infection was defined as a positive invasive diagnostic test (histology and/or urease test). Sensitivity (S), specificity (E) and positive (PPV) and negative (NPV) predictive values were obtained for HpSA and serum antibodies. Results: Ten children (26%) were infected with H pylori. S, E, PPV and NPV for HpSA were 90, 100, 100 and 97%, respectively. The figures for serum IgG were 81, 97, 89 and 93%, respectively and for IgA, 90, 76, 36 and 96%, respectively. Conclusions: HpSA was sensitive and specific as a clinical and epidemiological tool to evaluate H pylori infection in children. Serology was not as accurate, but IgG had a better performance than IgAinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.2 20072007-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200006es10.4067/S0034-98872007000200006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Antibodies, bacterial Helicobacter pylori Immunoglobulins
spellingShingle	Antibodies, bacterial Helicobacter pylori Immunoglobulins González F,Carmen Gloria Serrano H,Carolina Harris,Paul R Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposiciones
description	Background: During infancy, preventive, diagnostic and therapeutic efforts for Helicobacter pylori infection should be made. Aim: To evaluate non-invasive diagnostic methods such as stool antigen test (HpSA) and serum anti-H pylori antibody detection (IgG e IgA), compared to endoscopy-based invasive methods (histology and urease test) for the diagnosis of Helicobacter pylori infection. Patients and Methods: Thirty nine children (aged 3 to 14 years, 20 males) referred for upper gastrointestinal endoscopy, were studied. The gold standard to diagnose Helicobacter pylori infection was defined as a positive invasive diagnostic test (histology and/or urease test). Sensitivity (S), specificity (E) and positive (PPV) and negative (NPV) predictive values were obtained for HpSA and serum antibodies. Results: Ten children (26%) were infected with H pylori. S, E, PPV and NPV for HpSA were 90, 100, 100 and 97%, respectively. The figures for serum IgG were 81, 97, 89 and 93%, respectively and for IgA, 90, 76, 36 and 96%, respectively. Conclusions: HpSA was sensitive and specific as a clinical and epidemiological tool to evaluate H pylori infection in children. Serology was not as accurate, but IgG had a better performance than IgA
author	González F,Carmen Gloria Serrano H,Carolina Harris,Paul R
author_facet	González F,Carmen Gloria Serrano H,Carolina Harris,Paul R
author_sort	González F,Carmen Gloria
title	Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposiciones
title_short	Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposiciones
title_full	Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposiciones
title_fullStr	Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposiciones
title_full_unstemmed	Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposiciones
title_sort	diagnóstico de la infección poe helicobacter pylori en niños mediante la detección de antígenos en deposiciones
publisher	Sociedad Médica de Santiago
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200006
work_keys_str_mv	AT gonzalezfcarmengloria diagnosticodelainfeccionpoehelicobacterpylorienninosmedianteladetecciondeantigenosendeposiciones AT serranohcarolina diagnosticodelainfeccionpoehelicobacterpylorienninosmedianteladetecciondeantigenosendeposiciones AT harrispaulr diagnosticodelainfeccionpoehelicobacterpylorienninosmedianteladetecciondeantigenosendeposiciones
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Diagnóstico de la infección poe Helicobacter pylori en niños mediante la detección de antígenos en deposiciones

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