Distribución de las concentraciones de glucosa e indulina basal, HOMA IR Y MOMA ßcell en niños y adolescentes de la ciudad de Maracaibo, Venezuela

Background: The raising prevalence of obesity among children increases the risk of insulin resistance and its adverse metabolic consequences. Aim: To determine the distributions of fasting serum glucose, insulin, HOMA IR and HOMA ß cell in a representative sample of children and adolescents from Mar...

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Autores principales: Morales,Luz Marina, Raleigh,Xiomara, Fernández,Virginia, Molero-Conejo,Emperatriz
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200009
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spelling oai:scielo:S0034-988720070002000092007-03-28Distribución de las concentraciones de glucosa e indulina basal, HOMA IR Y MOMA ßcell en niños y adolescentes de la ciudad de Maracaibo, VenezuelaMorales,Luz MarinaRaleigh,XiomaraFernández,VirginiaMolero-Conejo,Emperatriz Beta cells, pancreatic Homeostasis Insulin resistance Obesity Background: The raising prevalence of obesity among children increases the risk of insulin resistance and its adverse metabolic consequences. Aim: To determine the distributions of fasting serum glucose, insulin, HOMA IR and HOMA ß cell in a representative sample of children and adolescents from Maracaibo-Venezuela. Subjects and Methods: Fasting insulin and glucose were measured in 418 children and adolescents (191 boys and 227 girls) of 7, 9, 11, 13, 15 years of age. HOMA IR and HOMA ß cell were calculated. Results: Insulin levels were lower in 7 and 9 year-old girls and 7 year-old boys compared with 11, 13 and 15 year-old girls and boys. Fasting glucose concentrations were similar in boys and girls. HOMA IR was lower in 7 year-old girls compared to 11, 13 and 15 years-old girls, whereas boys in every age showed similar values. HOMA ß cell was higher in 11 and 13 year-old girls. Conclusions: Our findings provide useful values to assess insulin resistance and ß-cell functioning in children and adolescentsinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.2 20072007-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200009es10.4067/S0034-98872007000200009
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Beta cells, pancreatic
Homeostasis
Insulin resistance
Obesity
spellingShingle Beta cells, pancreatic
Homeostasis
Insulin resistance
Obesity
Morales,Luz Marina
Raleigh,Xiomara
Fernández,Virginia
Molero-Conejo,Emperatriz
Distribución de las concentraciones de glucosa e indulina basal, HOMA IR Y MOMA ßcell en niños y adolescentes de la ciudad de Maracaibo, Venezuela
description Background: The raising prevalence of obesity among children increases the risk of insulin resistance and its adverse metabolic consequences. Aim: To determine the distributions of fasting serum glucose, insulin, HOMA IR and HOMA ß cell in a representative sample of children and adolescents from Maracaibo-Venezuela. Subjects and Methods: Fasting insulin and glucose were measured in 418 children and adolescents (191 boys and 227 girls) of 7, 9, 11, 13, 15 years of age. HOMA IR and HOMA ß cell were calculated. Results: Insulin levels were lower in 7 and 9 year-old girls and 7 year-old boys compared with 11, 13 and 15 year-old girls and boys. Fasting glucose concentrations were similar in boys and girls. HOMA IR was lower in 7 year-old girls compared to 11, 13 and 15 years-old girls, whereas boys in every age showed similar values. HOMA ß cell was higher in 11 and 13 year-old girls. Conclusions: Our findings provide useful values to assess insulin resistance and ß-cell functioning in children and adolescents
author Morales,Luz Marina
Raleigh,Xiomara
Fernández,Virginia
Molero-Conejo,Emperatriz
author_facet Morales,Luz Marina
Raleigh,Xiomara
Fernández,Virginia
Molero-Conejo,Emperatriz
author_sort Morales,Luz Marina
title Distribución de las concentraciones de glucosa e indulina basal, HOMA IR Y MOMA ßcell en niños y adolescentes de la ciudad de Maracaibo, Venezuela
title_short Distribución de las concentraciones de glucosa e indulina basal, HOMA IR Y MOMA ßcell en niños y adolescentes de la ciudad de Maracaibo, Venezuela
title_full Distribución de las concentraciones de glucosa e indulina basal, HOMA IR Y MOMA ßcell en niños y adolescentes de la ciudad de Maracaibo, Venezuela
title_fullStr Distribución de las concentraciones de glucosa e indulina basal, HOMA IR Y MOMA ßcell en niños y adolescentes de la ciudad de Maracaibo, Venezuela
title_full_unstemmed Distribución de las concentraciones de glucosa e indulina basal, HOMA IR Y MOMA ßcell en niños y adolescentes de la ciudad de Maracaibo, Venezuela
title_sort distribución de las concentraciones de glucosa e indulina basal, homa ir y moma ßcell en niños y adolescentes de la ciudad de maracaibo, venezuela
publisher Sociedad Médica de Santiago
publishDate 2007
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000200009
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