Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana

Background: Helicobacter pylori is a pathogenic bacterium that infects a significant number of individuals. At present, therapeutic strategies to eradicate this bacterium depend on our knowledge of its resistance to antimicrobials. Aims: To evaluate the primary resistance of H pylori to metronidazol...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Vallejos M,Cristian, Garrido O,Leonardo, Cáceres L,Dante, Madrid,Ana María, Defilippi,Claudia, Defilippi C,Carlos, Toledo A,Héctor
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2007
Materias:	Clarithromycin Drug resistance, microbial Helicobacter pylori Metronidazole Tetracycline
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000300002
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0034-98872007000300002
record_format	dspace
spelling	oai:scielo:S0034-988720070003000022014-01-06Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región MetropolitanaVallejos M,CristianGarrido O,LeonardoCáceres L,DanteMadrid,Ana MaríaDefilippi,ClaudiaDefilippi C,CarlosToledo A,Héctor Clarithromycin Drug resistance, microbial Helicobacter pylori Metronidazole Tetracycline Background: Helicobacter pylori is a pathogenic bacterium that infects a significant number of individuals. At present, therapeutic strategies to eradicate this bacterium depend on our knowledge of its resistance to antimicrobials. Aims: To evaluate the primary resistance of H pylori to metronidazole (Mtz), clarithromycin (Cla), and tetracycline (Tet) in symptomatic out-patients. Material and Methods: Fifty independent isolates of H pylori were obtained by endoscopy-assisted gastric biopsy from patients attending the University of Chile Clinical Hospital, that previously had not been treated with an eradication regime against this bacterium. The minimal inhibitory concentration of each antimicrobial was determined by agar dilution method. Results: Forty five and 27% of the isolates were found to be resistant to Mtz and Tet, respectively; the majority of these resistant isolates were from patients older than 21 years. Twenty percent of isolates were resistant to Cla; these were distributed evenly among different ages. Thirty two percent of the isolates were resistant to two or more of the antimicrobials. Conclusions: The high frequency of naturally occurring, antimicrobial-resistant strains of H pylori poses a national and world-wide problem for public healthinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.3 20072007-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000300002es10.4067/S0034-98872007000300002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Clarithromycin Drug resistance, microbial Helicobacter pylori Metronidazole Tetracycline
spellingShingle	Clarithromycin Drug resistance, microbial Helicobacter pylori Metronidazole Tetracycline Vallejos M,Cristian Garrido O,Leonardo Cáceres L,Dante Madrid,Ana María Defilippi,Claudia Defilippi C,Carlos Toledo A,Héctor Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana
description	Background: Helicobacter pylori is a pathogenic bacterium that infects a significant number of individuals. At present, therapeutic strategies to eradicate this bacterium depend on our knowledge of its resistance to antimicrobials. Aims: To evaluate the primary resistance of H pylori to metronidazole (Mtz), clarithromycin (Cla), and tetracycline (Tet) in symptomatic out-patients. Material and Methods: Fifty independent isolates of H pylori were obtained by endoscopy-assisted gastric biopsy from patients attending the University of Chile Clinical Hospital, that previously had not been treated with an eradication regime against this bacterium. The minimal inhibitory concentration of each antimicrobial was determined by agar dilution method. Results: Forty five and 27% of the isolates were found to be resistant to Mtz and Tet, respectively; the majority of these resistant isolates were from patients older than 21 years. Twenty percent of isolates were resistant to Cla; these were distributed evenly among different ages. Thirty two percent of the isolates were resistant to two or more of the antimicrobials. Conclusions: The high frequency of naturally occurring, antimicrobial-resistant strains of H pylori poses a national and world-wide problem for public health
author	Vallejos M,Cristian Garrido O,Leonardo Cáceres L,Dante Madrid,Ana María Defilippi,Claudia Defilippi C,Carlos Toledo A,Héctor
author_facet	Vallejos M,Cristian Garrido O,Leonardo Cáceres L,Dante Madrid,Ana María Defilippi,Claudia Defilippi C,Carlos Toledo A,Héctor
author_sort	Vallejos M,Cristian
title	Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana
title_short	Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana
title_full	Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana
title_fullStr	Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana
title_full_unstemmed	Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana
title_sort	prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en helicobacter pylori aislado de pacientes de la región metropolitana
publisher	Sociedad Médica de Santiago
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000300002
work_keys_str_mv	AT vallejosmcristian prevalenciadelaresistenciaametrodinazolclaritromicinaytetraciclinaenhelicobacterpyloriaisladodepacientesdelaregionmetropolitana AT garridooleonardo prevalenciadelaresistenciaametrodinazolclaritromicinaytetraciclinaenhelicobacterpyloriaisladodepacientesdelaregionmetropolitana AT caceresldante prevalenciadelaresistenciaametrodinazolclaritromicinaytetraciclinaenhelicobacterpyloriaisladodepacientesdelaregionmetropolitana AT madridanamaria prevalenciadelaresistenciaametrodinazolclaritromicinaytetraciclinaenhelicobacterpyloriaisladodepacientesdelaregionmetropolitana AT defilippiclaudia prevalenciadelaresistenciaametrodinazolclaritromicinaytetraciclinaenhelicobacterpyloriaisladodepacientesdelaregionmetropolitana AT defilippiccarlos prevalenciadelaresistenciaametrodinazolclaritromicinaytetraciclinaenhelicobacterpyloriaisladodepacientesdelaregionmetropolitana AT toledoahector prevalenciadelaresistenciaametrodinazolclaritromicinaytetraciclinaenhelicobacterpyloriaisladodepacientesdelaregionmetropolitana
_version_	1718436309157019648

Prevalencia de la resistencia a metrodinazol, claritromicina y tetraciclina en Helicobacter pylori aislado de pacientes de la Región Metropolitana

Ejemplares similares