Un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en Santiago, Chile

Background: Depression is a public health problem, due to its high prevalence and its associated disability. Aim: To compare a pharmacological intervention for depression controlled by phone from a central level (TM) and the usual treatment (TH) in a randomized clinical trial. Material and methods:...

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Autores principales: Fritsch,Rosemarie, Araya,Ricardo, Solís,Jaime, Montt,Elena, Pilowsky,Daniel, Rojas,Graciela
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000500006
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spelling oai:scielo:S0034-988720070005000062007-07-09Un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en Santiago, ChileFritsch,RosemarieAraya,RicardoSolís,JaimeMontt,ElenaPilowsky,DanielRojas,Graciela Compliance Depression Drug therapy Background: Depression is a public health problem, due to its high prevalence and its associated disability. Aim: To compare a pharmacological intervention for depression controlled by phone from a central level (TM) and the usual treatment (TH) in a randomized clinical trial. Material and methods: Three hundred and forty five women, aged 22 to 59 years were studied. They were randomly assigned to receive the usual therapy or a pharmacological intervention with periodical telephone contacts with medical collaboration personnel, to reinforce compliance with treatment and educate about the disease. Women were blindly evaluated at 3 and 6 months with the Hamilton depression rating score (HDRS) and the SF-36 to assess depressive symptoms and quality of life, respectively. Results: In both evaluations, improvement was significantly greater in the TM group than the TH group. At 3 months, improvement was higher in the TM group in the subscales of physical function, pain, general health, energy, emotional role, mental health and standardized physical and psychic scales of SF-36. At 6 months, this significant difference in favour of TM was maintained for energy, mental health and the standardized psychic scale. Conclusions: A telephone reinforcement improves the outcomes of treatments for depressioninfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.5 20072007-05-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000500006es10.4067/S0034-98872007000500006
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Compliance
Depression
Drug therapy
spellingShingle Compliance
Depression
Drug therapy
Fritsch,Rosemarie
Araya,Ricardo
Solís,Jaime
Montt,Elena
Pilowsky,Daniel
Rojas,Graciela
Un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en Santiago, Chile
description Background: Depression is a public health problem, due to its high prevalence and its associated disability. Aim: To compare a pharmacological intervention for depression controlled by phone from a central level (TM) and the usual treatment (TH) in a randomized clinical trial. Material and methods: Three hundred and forty five women, aged 22 to 59 years were studied. They were randomly assigned to receive the usual therapy or a pharmacological intervention with periodical telephone contacts with medical collaboration personnel, to reinforce compliance with treatment and educate about the disease. Women were blindly evaluated at 3 and 6 months with the Hamilton depression rating score (HDRS) and the SF-36 to assess depressive symptoms and quality of life, respectively. Results: In both evaluations, improvement was significantly greater in the TM group than the TH group. At 3 months, improvement was higher in the TM group in the subscales of physical function, pain, general health, energy, emotional role, mental health and standardized physical and psychic scales of SF-36. At 6 months, this significant difference in favour of TM was maintained for energy, mental health and the standardized psychic scale. Conclusions: A telephone reinforcement improves the outcomes of treatments for depression
author Fritsch,Rosemarie
Araya,Ricardo
Solís,Jaime
Montt,Elena
Pilowsky,Daniel
Rojas,Graciela
author_facet Fritsch,Rosemarie
Araya,Ricardo
Solís,Jaime
Montt,Elena
Pilowsky,Daniel
Rojas,Graciela
author_sort Fritsch,Rosemarie
title Un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en Santiago, Chile
title_short Un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en Santiago, Chile
title_full Un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en Santiago, Chile
title_fullStr Un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en Santiago, Chile
title_full_unstemmed Un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en Santiago, Chile
title_sort un ensayo clínico aleatorizado de farmacoterapia con monitorización telefónica para mejorar el tratamiento de la depresión en la atención primaria en santiago, chile
publisher Sociedad Médica de Santiago
publishDate 2007
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000500006
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