Carcinoma familiar del tiroides no medular (CFTNM): características de presentación en 17 casos

Background: Papillary thyroid carcinoma can have familial aggregation. Aim: To compare retrospectively familial non medullary thyroid carcinoma (FNMTC) with sporadic papillary thyroid carcinoma (PTC). Material and methods: Retrospective analysis of medical records of patients with thyroid carcinoma....

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Autores principales: Mosso,Lorena, Velasco,Soledad, Salazar,Iván, Solar,Antonieta, González,Hernán, Cardona,Belinda, Fardella,Carlos, González,Gilberto, López,José Manuel, Rodríguez,José Adolfo, Cruz,Francisco, Arteaga,Eugenio
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000600005
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spelling oai:scielo:S0034-988720070006000052014-01-06Carcinoma familiar del tiroides no medular (CFTNM): características de presentación en 17 casosMosso,LorenaVelasco,SoledadSalazar,IvánSolar,AntonietaGonzález,HernánCardona,BelindaFardella,CarlosGonzález,GilbertoLópez,José ManuelRodríguez,José AdolfoCruz,FranciscoArteaga,Eugenio Carcinoma, papillary Thyroiditis Thyroid neoplasms Background: Papillary thyroid carcinoma can have familial aggregation. Aim: To compare retrospectively familial non medullary thyroid carcinoma (FNMTC) with sporadic papillary thyroid carcinoma (PTC). Material and methods: Retrospective analysis of medical records of patients with thyroid carcinoma. An index case was defined as a subject with the diagnosis of differentiated thyroid carcinoma with one or more first degree relatives with the same type of cancer. Seventeen such patients were identified and were compared with 352 subjects with PTC. Results: The most common affected relatives were sisters. Patients with FNMTC were younger than those with PTC. No differences were observed in gender, single or multiple foci, thyroid capsule involvement, surgical border involvement, number of affected lymph nodes and coexistence of follicular hyperplasia. Patients with FNMTC had smaller tumors and had a nine times more common association with lymphocytic thyroiditis. Five patients with FNMTC had local recurrence during 4.8 years of follow up. Conclusions: Patients with FNMTC commonly have an associated chronic thyroiditis, are younger and have smaller tumors than patients with PTCinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.6 20072007-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000600005es10.4067/S0034-98872007000600005
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Carcinoma, papillary
Thyroiditis
Thyroid neoplasms
spellingShingle Carcinoma, papillary
Thyroiditis
Thyroid neoplasms
Mosso,Lorena
Velasco,Soledad
Salazar,Iván
Solar,Antonieta
González,Hernán
Cardona,Belinda
Fardella,Carlos
González,Gilberto
López,José Manuel
Rodríguez,José Adolfo
Cruz,Francisco
Arteaga,Eugenio
Carcinoma familiar del tiroides no medular (CFTNM): características de presentación en 17 casos
description Background: Papillary thyroid carcinoma can have familial aggregation. Aim: To compare retrospectively familial non medullary thyroid carcinoma (FNMTC) with sporadic papillary thyroid carcinoma (PTC). Material and methods: Retrospective analysis of medical records of patients with thyroid carcinoma. An index case was defined as a subject with the diagnosis of differentiated thyroid carcinoma with one or more first degree relatives with the same type of cancer. Seventeen such patients were identified and were compared with 352 subjects with PTC. Results: The most common affected relatives were sisters. Patients with FNMTC were younger than those with PTC. No differences were observed in gender, single or multiple foci, thyroid capsule involvement, surgical border involvement, number of affected lymph nodes and coexistence of follicular hyperplasia. Patients with FNMTC had smaller tumors and had a nine times more common association with lymphocytic thyroiditis. Five patients with FNMTC had local recurrence during 4.8 years of follow up. Conclusions: Patients with FNMTC commonly have an associated chronic thyroiditis, are younger and have smaller tumors than patients with PTC
author Mosso,Lorena
Velasco,Soledad
Salazar,Iván
Solar,Antonieta
González,Hernán
Cardona,Belinda
Fardella,Carlos
González,Gilberto
López,José Manuel
Rodríguez,José Adolfo
Cruz,Francisco
Arteaga,Eugenio
author_facet Mosso,Lorena
Velasco,Soledad
Salazar,Iván
Solar,Antonieta
González,Hernán
Cardona,Belinda
Fardella,Carlos
González,Gilberto
López,José Manuel
Rodríguez,José Adolfo
Cruz,Francisco
Arteaga,Eugenio
author_sort Mosso,Lorena
title Carcinoma familiar del tiroides no medular (CFTNM): características de presentación en 17 casos
title_short Carcinoma familiar del tiroides no medular (CFTNM): características de presentación en 17 casos
title_full Carcinoma familiar del tiroides no medular (CFTNM): características de presentación en 17 casos
title_fullStr Carcinoma familiar del tiroides no medular (CFTNM): características de presentación en 17 casos
title_full_unstemmed Carcinoma familiar del tiroides no medular (CFTNM): características de presentación en 17 casos
title_sort carcinoma familiar del tiroides no medular (cftnm): características de presentación en 17 casos
publisher Sociedad Médica de Santiago
publishDate 2007
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000600005
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