Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológica

Background: Interpretation of abnormal foci with high tracer uptake may require morphological correlation. Fusion of functional images obtained by single photon emission computed tomography (SPECT) and anatomical images obtained by computed tomography (CT) or magnetic resonance (RM) allows an integr...

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Autores principales:	Aqueveque A,Carolina, González E,Patricio, Gutiérrez B,Daniela, Jaimovich F,Rodrigo, Díaz P,Juan Carlos, Csendes G,Paula, Orellana P,Patricia, Lavados M,Hugo, Alliende G,Isabel, Araya L,Sandra
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2007
Materias:	Magnetic resonance imaging Thyroid neoplasms Tomography emission-computed, Single-photon
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000600006
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spelling	oai:scielo:S0034-988720070006000062014-01-06Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológicaAqueveque A,CarolinaGonzález E,PatricioGutiérrez B,DanielaJaimovich F,RodrigoDíaz P,Juan CarlosCsendes G,PaulaOrellana P,PatriciaLavados M,HugoAlliende G,IsabelAraya L,Sandra Magnetic resonance imaging Thyroid neoplasms Tomography emission-computed, Single-photon Background: Interpretation of abnormal foci with high tracer uptake may require morphological correlation. Fusion of functional images obtained by single photon emission computed tomography (SPECT) and anatomical images obtained by computed tomography (CT) or magnetic resonance (RM) allows an integrated comprehension of complementary information. Aim To demonstrate that SPECT/CT fusion with external markers is useful in clinical practice to clarify the location and pathological meaning of questionable foci. Material and methods: Thirty four pairs of images from separate equipments (31 SPECT/CT and 3 SPECT/RM) pertaining to 29 patients, were fused. Fifty one foci of abnormal tracer uptake of uncertain pathological meaning were analyzed. These were classified before and after the fusion as probably malignant or probably benign. Results: Seventy percent of patients had a differentiated thyroid carcinoma. The fusion localized 100% of foci. Nine percent had a normal and 26% an abnormal anatomy. Before fusion 82% of foci were classified as potentially malignant. This figure changed to 59% after the fusion (p <0.01). Therefore the suspicion of malignancy was presumptively confirmed in 72% of foci and fusion results would have reached a 27% of incremental diagnostic value in 14 cases that changed of category (11 with differentiated thyroid carcinoma, one with colorectal cancer, one with a nasalEwingsarcoma and one with a brain tumor). Conclusions: The fusion of SPECT and CT is useful in selected patients, specially those with differentiated thyroid carcinoma. The fusion of SPECT and RM is also feasibleinfo:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.135 n.6 20072007-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000600006es10.4067/S0034-98872007000600006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Magnetic resonance imaging Thyroid neoplasms Tomography emission-computed, Single-photon
spellingShingle	Magnetic resonance imaging Thyroid neoplasms Tomography emission-computed, Single-photon Aqueveque A,Carolina González E,Patricio Gutiérrez B,Daniela Jaimovich F,Rodrigo Díaz P,Juan Carlos Csendes G,Paula Orellana P,Patricia Lavados M,Hugo Alliende G,Isabel Araya L,Sandra Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológica
description	Background: Interpretation of abnormal foci with high tracer uptake may require morphological correlation. Fusion of functional images obtained by single photon emission computed tomography (SPECT) and anatomical images obtained by computed tomography (CT) or magnetic resonance (RM) allows an integrated comprehension of complementary information. Aim To demonstrate that SPECT/CT fusion with external markers is useful in clinical practice to clarify the location and pathological meaning of questionable foci. Material and methods: Thirty four pairs of images from separate equipments (31 SPECT/CT and 3 SPECT/RM) pertaining to 29 patients, were fused. Fifty one foci of abnormal tracer uptake of uncertain pathological meaning were analyzed. These were classified before and after the fusion as probably malignant or probably benign. Results: Seventy percent of patients had a differentiated thyroid carcinoma. The fusion localized 100% of foci. Nine percent had a normal and 26% an abnormal anatomy. Before fusion 82% of foci were classified as potentially malignant. This figure changed to 59% after the fusion (p <0.01). Therefore the suspicion of malignancy was presumptively confirmed in 72% of foci and fusion results would have reached a 27% of incremental diagnostic value in 14 cases that changed of category (11 with differentiated thyroid carcinoma, one with colorectal cancer, one with a nasalEwingsarcoma and one with a brain tumor). Conclusions: The fusion of SPECT and CT is useful in selected patients, specially those with differentiated thyroid carcinoma. The fusion of SPECT and RM is also feasible
author	Aqueveque A,Carolina González E,Patricio Gutiérrez B,Daniela Jaimovich F,Rodrigo Díaz P,Juan Carlos Csendes G,Paula Orellana P,Patricia Lavados M,Hugo Alliende G,Isabel Araya L,Sandra
author_facet	Aqueveque A,Carolina González E,Patricio Gutiérrez B,Daniela Jaimovich F,Rodrigo Díaz P,Juan Carlos Csendes G,Paula Orellana P,Patricia Lavados M,Hugo Alliende G,Isabel Araya L,Sandra
author_sort	Aqueveque A,Carolina
title	Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológica
title_short	Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológica
title_full	Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológica
title_fullStr	Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológica
title_full_unstemmed	Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológica
title_sort	utilidad clínica de la fusión spect/ct con marcadores externos en patología oncológica
publisher	Sociedad Médica de Santiago
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872007000600006
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Utilidad clínica de la fusión SPECT/CT con marcadores externos en patología oncológica

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